Reactome | VEGFR2 [plasma membrane]

VEGFR2 [plasma membrane]

Stable Identifier

R-MMU-195382

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

plasma membrane

Synonyms

P35918

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P35918 Kdr

Gene Names

Kdr, Flk-1, Flk1

Chain

signal peptide:1-19, chain:20-1367

Reference Genes

UCSC:P35918 Kdr

Participant Of

input

hasComponent

Other forms of this molecule

Mouse Vegfr2-Human CSF1R fusion protein [plasma membrane]

phospho-p-6Y-VEGFR2 [plasma membrane]

Inferred From

VEGFR2 [plasma membrane] (Homo sapiens)

Cross References

ZINC - Investigational

VGFR2_MOUSE

ZINC - World Drugs

VGFR2_MOUSE

ZINC - FDA approved

VGFR2_MOUSE

ZINC - Substances

VGFR2_MOUSE

ZINC target

P35918

PRO

P35918

ZINC - Predictions - Purchasable

VGFR2_MOUSE

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P08581 MET	7	p-Y1349,Y1356-MET [plasma membrane] (R-HSA-6807032) p-Y1234,Y1235,Y1356-MET [plasma membrane] (R-HSA-6807014) MonoUb-K,p-Y1234,Y1235,Y1349,Y1356-MET [plasma membrane] (R-HSA-8875181) MonoUb-K,p-Y1003,4Y-MET [plasma membrane] (R-HSA-8875180) p-Y1003,4Y-MET [plasma membrane] (R-HSA-8874689) MET [plasma membrane] (R-HSA-419603) p-Y1234,Y1235,Y1349,Y1356-MET [plasma membrane] (R-HSA-6806973)	0.591	3
UniProt:P16056	7	phospho-p-Y1349,Y1356-MET [plasma membrane] (R-MMU-6807032) phospho-p-Y1234,Y1235,Y1356-MET [plasma membrane] (R-MMU-6807014) phospho-MonoUb-K,p-Y1234,Y1235,Y1349,Y1356-MET [plasma membrane] (R-MMU-8875181) phospho-MonoUb-K,p-Y1003,4Y-MET [plasma membrane] (R-MMU-8875180) phospho-p-Y1003,4Y-MET [plasma membrane] (R-MMU-8874689) MET [plasma membrane] (R-MMU-419603) phospho-p-Y1234,Y1235,Y1349,Y1356-MET [plasma membrane] (R-MMU-6806973)	0.591	3
UniProt:P35917	1	FLT4 [plasma membrane] (R-MMU-195359)	0.564	3
UniProt:P09619 PDGFRB	3	PDGFRB [plasma membrane] (R-HSA-186767) p-11Y-PDGFRB [plasma membrane] (R-HSA-8864039) p-12Y-PDGFRB [plasma membrane] (R-HSA-186803)	0.524	4
UniProt:Q62077 Plcg1	10	Plcg1 [cytosol] (R-MMU-9638030) p-Y-Plcg1 [cytosol] (R-MMU-9029083) p-4Y-Plcg1 [plasma membrane] (R-MMU-9030452) P-Plcg1 [cytosol] (R-MMU-1251936) Plcg1 [plasma membrane] (R-MMU-1251925) phospho-p-Y771,Y783-PLCG1 [plasma membrane] (R-MMU-1169084) PLCG1 [plasma membrane] (R-MMU-167682) PLCG1 [cytosol] (R-MMU-202320) phospho-p-Y771,Y783,Y1254-PLCG1 [cytosol] (R-MMU-202357) phospho-p-4Y-PLCG1 [plasma membrane] (R-MMU-167679)	0.462	2