Reactome | phospho-Prkce [plasma membrane]

phospho-Prkce [plasma membrane]

Stable Identifier

R-MMU-198260

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

plasma membrane

Synonyms

p-T566,T710,S729-PRKCE, P16054

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P16054

Gene Names

Prkce

Reference Genes

BioGPS Gene:18754 Prkce

ENSEMBL:ENSMUSG00000045038

ENSEMBL:ENSMUSG00000045038 Prkce

KEGG Gene (Mus musculus):18754 Prkce

Monarch:18754 Prkce

NCBI Gene:18754 Prkce

UCSC:P16054 Prkce

Reference Transcript

RefSeq:NM_011104.3 Prkce

Other Identifiers

103223_at

10447294

111126_at

1437861_s_at

1449956_at

1452878_at

17340177

18754

4320374

4321651

4359212

4416634

4549422

4675147

5009129

5035506

5196962

5213384

5243677

5293313

5317447

5334612

5339192

5391757

5453461

5468155

5521798

5533952

5612604

94161_at

AA198947_at

A_51_P352782

A_52_P31593

A_52_P375455

A_55_P2007944

GE35903

GO:0003674

GO:0004672

GO:0004674

GO:0004697

GO:0004699

GO:0005524

GO:0006464

GO:0006468

GO:0007165

GO:0008150

GO:0016301

GO:0035556

GO:0043167

ILMN_2435477

ILMN_2771063

ILMN_2993204

mMC023955

mMC024870

Participates

as a member of

Phospho-PKC-delta/epsilon [plasma membrane] (Mus musculus)

as a component of

DAGs:active p-T566,T710,S729-PRKCE [plasma membrane] (Mus musculus)

Other forms of this molecule

Prkce [cytosol]

Inferred From

p-T566,T710,S729-PRKCE [plasma membrane] (Homo sapiens)

Modified Residues

Name

O-phospho-L-threonine at 566 (in Homo sapiens)

Coordinate

566

PsiMod Name

O-phospho-L-threonine [MOD:00047]

PsiMod Definition

A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.

Name

O-phospho-L-threonine at 710 (in Homo sapiens)

Coordinate

710

PsiMod Name

O-phospho-L-threonine [MOD:00047]

PsiMod Definition

A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.

Name

O-phospho-L-serine at 729 (in Homo sapiens)

Coordinate

729

PsiMod Name

O-phospho-L-serine [MOD:00046]

PsiMod Definition

A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.

Cross References

RefSeq

NP_035234.1

ZINC target

P16054

Ensembl

ENSMUSP00000094873, ENSMUSP00000094874, ENSMUST00000097275, ENSMUST00000097274, ENSMUSG00000045038

PRO

P16054

ZINC - Predictions - Purchasable

KPCE_MOUSE

MGI

97599

Interactors (8)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9CQV8 Ywhab	1	14-3-3 beta/alpha [cytosol] (R-MMU-1445100)	0.725	6
UniProt:P35438 Grin1	3	Grin1 [endoplasmic reticulum membrane] (R-MMU-9610359) Grin1 [plasma membrane] (R-MMU-3928395) Grin1 [transport vesicle membrane] (R-MMU-9610566)	0.643	4
UniProt:P20152	9	Vim [cytosol] (R-MMU-350294) Vim [cytosol] (R-MMU-350264) Vim [cytosol] (R-MMU-350316) Vim [cytosol] (R-MMU-350317) Vim [cytosol] (R-MMU-350314) Vim [cytosol] (R-MMU-350323) Vim [cytosol] (R-MMU-201600) Vim [microtubule organizing center] (R-MMU-9657898) Vim [cytosol] (R-MMU-9646687)	0.641	3
UniProt:P23242	6	Gja1 [Golgi membrane] (R-MMU-190649) Gja1 [endoplasmic reticulum membrane] (R-MMU-190654) Gja1 [lysosomal membrane] (R-MMU-196173) phospho-Gja1 [plasma membrane] (R-MMU-191657) Gja1 [Golgi-associated vesicle membrane] (R-MMU-190544) Gja1 [plasma membrane] (R-MMU-158058)	0.564	3
UniProt:P60710 Actb	4	Actb [nucleoplasm] (R-MMU-3321990) Actb [lysosomal membrane] (R-MMU-196160) Actin, cytoplasmic 1 [cytosol] (R-MMU-2263470) Actb [plasma membrane] (R-MMU-196016)	0.524	2
UniProt:Q9WVM1	1	Racgap1 [cytosol] (R-MMU-195122)	0.524	2
UniProt:Q921I1	6	Tf [secretory granule lumen] (R-MMU-350704) Tf [clathrin-coated endocytic vesicle membrane] (R-MMU-8869140) phospho-Tf [endoplasmic reticulum lumen] (R-MMU-8957001) Tf [endoplasmic reticulum lumen] (R-MMU-8956763) Tf [endosome membrane] (R-MMU-917974) Tf [extracellular region] (R-MMU-350754)	0.524	2
UniProt:P07356 Anxa2	4	Anxa2 [external side of plasma membrane] (R-MMU-5336164) Anxa2 [cytosol] (R-MMU-5333007) Anxa2 [extracellular region] (R-MMU-6806242) Anxa2 [azurophil granule lumen] (R-MMU-6798766)	0.524	2