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p-T,p-S-AKT [cytosol]
Stable Identifier
R-MMU-202074
Type
Set [CandidateSet]
Species
Mus musculus
Compartment
cytosol
Synonyms
Active AKT
Locations in the PathwayBrowser
Expand all
Cell Cycle (Mus musculus)
Cell Cycle, Mitotic (Mus musculus)
Mitotic G1 phase and G1/S transition (Mus musculus)
G1/S Transition (Mus musculus)
Cyclin E associated events during G1/S transition (Mus musculus)
AKT phosphorylates p21Cip1 and p27Kip1 (Mus musculus)
p-T,p-S-AKT [cytosol] (Mus musculus)
S Phase (Mus musculus)
Cyclin A:Cdk2-associated events at S phase entry (Mus musculus)
AKT phosphorylates p21Cip1 and p27Kip1 (Mus musculus)
p-T,p-S-AKT [cytosol] (Mus musculus)
Cellular responses to stimuli (Mus musculus)
Cellular responses to stress (Mus musculus)
Cellular response to chemical stress (Mus musculus)
KEAP1-NFE2L2 pathway (Mus musculus)
NFE2L2 translocates from cytosol to nucleoplasm (Mus musculus)
p-T,p-S-AKT [cytosol] (Mus musculus)
Gene expression (Transcription) (Mus musculus)
RNA Polymerase II Transcription (Mus musculus)
Generic Transcription Pathway (Mus musculus)
Transcriptional Regulation by TP53 (Mus musculus)
Regulation of TP53 Activity (Mus musculus)
Regulation of TP53 Expression and Degradation (Mus musculus)
Regulation of TP53 Degradation (Mus musculus)
AKT phosphorylates MDM2 (Mus musculus)
p-T,p-S-AKT [cytosol] (Mus musculus)
TP53 Regulates Metabolic Genes (Mus musculus)
AKT phosphorylates TSC2, inhibiting it (Mus musculus)
p-T,p-S-AKT [cytosol] (Mus musculus)
Immune System (Mus musculus)
Adaptive Immune System (Mus musculus)
Costimulation by the CD28 family (Mus musculus)
CD28 co-stimulation (Mus musculus)
CD28 dependent PI3K/Akt signaling (Mus musculus)
AKT interacts and phosphorylates Cot (Mus musculus)
p-T,p-S-AKT [cytosol] (Mus musculus)
CTLA4 inhibitory signaling (Mus musculus)
Dephosphorylation of AKT by PP2A (Mus musculus)
p-T,p-S-AKT [cytosol] (Mus musculus)
Signal Transduction (Mus musculus)
Intracellular signaling by second messengers (Mus musculus)
PIP3 activates AKT signaling (Mus musculus)
AKT phosphorylates targets in the cytosol (Mus musculus)
AKT phosphorylates AKT1S1 (PRAS40) (Mus musculus)
p-T,p-S-AKT [cytosol] (Mus musculus)
AKT phosphorylates IKKalpha (Mus musculus)
p-T,p-S-AKT [cytosol] (Mus musculus)
AKT phosphorylates MDM2 (Mus musculus)
p-T,p-S-AKT [cytosol] (Mus musculus)
AKT phosphorylates MKRN1 (Mus musculus)
p-T,p-S-AKT [cytosol] (Mus musculus)
AKT phosphorylates TSC2, inhibiting it (Mus musculus)
p-T,p-S-AKT [cytosol] (Mus musculus)
AKT phosphorylates caspase-9 (Mus musculus)
p-T,p-S-AKT [cytosol] (Mus musculus)
AKT phosphorylates p21Cip1 and p27Kip1 (Mus musculus)
p-T,p-S-AKT [cytosol] (Mus musculus)
Negative regulation of the PI3K/AKT network (Mus musculus)
PHLPP dephosphorylates S473 in AKT (Mus musculus)
p-T,p-S-AKT [cytosol] (Mus musculus)
PTEN Regulation (Mus musculus)
Regulation of PTEN stability and activity (Mus musculus)
AKT phosphorylates MKRN1 (Mus musculus)
p-T,p-S-AKT [cytosol] (Mus musculus)
Signaling by Receptor Tyrosine Kinases (Mus musculus)
Signaling by ERBB2 (Mus musculus)
Downregulation of ERBB2 signaling (Mus musculus)
Downregulation of ERBB2:ERBB3 signaling (Mus musculus)
Phosphorylation of USP8 by P-AKT (Mus musculus)
p-T,p-S-AKT [cytosol] (Mus musculus)
Vesicle-mediated transport (Mus musculus)
Membrane Trafficking (Mus musculus)
Rab regulation of trafficking (Mus musculus)
RAB GEFs exchange GTP for GDP on RABs (Mus musculus)
Active AKT phosphorylates DENND1A and DENND1B in response to insulin signaling (Mus musculus)
p-T,p-S-AKT [cytosol] (Mus musculus)
Participants
members
phospho-p-T308,S473-AKT1 [cytosol]
(Mus musculus)
candidates
phospho-p-T309,S474-AKT2 [cytosol]
(Mus musculus)
phospho-p-T305,S472-AKT3 [cytosol]
(Mus musculus)
Participates
as an input of
Dephosphorylation of AKT by PP2A (Mus musculus)
PHLPP dephosphorylates S473 in AKT (Mus musculus)
This entity regulates
Positively
NFE2L2 translocates from cytosol to nucleoplasm
(Mus musculus)
Inferred From
p-T,p-S-AKT [cytosol]
(Homo sapiens)
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