Reactome | Lox [extracellular region]

Lox [extracellular region]

Stable Identifier

R-MMU-2022074

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

extracellular region

Synonyms

LOX(22-168), P28301

Locations in the PathwayBrowser

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Extracellular matrix organization (Mus musculus)

- Collagen formation (Mus musculus)
  - Assembly of collagen fibrils and other multimeric structures (Mus musculus)
    - Crosslinking of collagen fibrils (Mus musculus)
      - Prolysyl oxidase activation (Mus musculus)
        
        Lysyl oxidase propeptides [extracellular region] (Mus musculus)
        
        Lox [extracellular region] (Mus musculus)

External Reference Information

External Reference

UniProt:P28301

Gene Names

Lox

Reference Genes

BioGPS Gene:16948 Lox

ENSEMBL:ENSMUSG00000024529

ENSEMBL:ENSMUSG00000024529 Lox

KEGG Gene (Mus musculus):16948 Lox

Monarch:16948 Lox

NCBI Gene:16948 Lox

UCSC:P28301 Lox

Reference Transcript

Other Identifiers

10458894

1416121_at

1448228_at

160095_at

16948

17354367

4318934

4345358

4397724

4412677

4464637

4642560

4826127

4881489

4949412

4985446

5013029

5161375

5193764

5205222

5214922

5466056

5517991

5537309

5566212

5594069

5609787

A_51_P300493

A_55_P2032678

A_66_P138929

GE35694

GO:0003674

GO:0005507

GO:0008150

GO:0016491

GO:0016641

GO:0043167

GO:0055114

ILMN_1227261

ILMN_2997494

l04262_s_at

mMC016520

Participates

as a member of

Lysyl oxidase propeptides [extracellular region] (Mus musculus)

Other forms of this molecule

Lox [extracellular region]

Inferred From

LOX(22-168) [extracellular region] (Homo sapiens)

Cross References

RefSeq

NP_001273110.1, NP_001273111.1, NP_034858.2

Ensembl

ENSMUSG00000024529, ENSMUSP00000129247, ENSMUSP00000025409, ENSMUST00000025409, ENSMUST00000171470

PRO

P28301

MGI

96817

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P04049 RAF1	54	p-S621-RAF1 S257L [cytosol] (R-HSA-9656121) p-S621-RAF1 S259F [cytosol] (R-HSA-9656124) p-S621-RAF1 P261L [cytosol] (R-HSA-9656106) p-S621-RAF1 N262K [cytosol] (R-HSA-9656101) p-S621-RAF1 P261A [cytosol] (R-HSA-9656103) p-S621-RAF1 P261S [cytosol] (R-HSA-9656113) p-S621-RAF1 S259T [cytosol] (R-HSA-9656130) p-S621-RAF1 P261T [cytosol] (R-HSA-9656115) p-S621-RAF1 P261R [cytosol] (R-HSA-9656110) p-S621-RAF1 S259P [cytosol] (R-HSA-9656127) p-S621-RAF1 T260I [cytosol] (R-HSA-9656136) p-S621-RAF1 T260R [cytosol] (R-HSA-9656139) p-S621-RAF1 V263A [cytosol] (R-HSA-9656148) p-S621-RAF1 R256S [cytosol] (R-HSA-9656119) p-S621-RAF1 T491I [cytosol] (R-HSA-9656143) p-S621-RAF1 D486N [cytosol] (R-HSA-9656088) p-S621-RAF1 S427G [cytosol] (R-HSA-9656134) p-S621-RAF1 L613V [cytosol] (R-HSA-9656098) p-S621-RAF1 G361A [cytosol] (R-HSA-9656092) p-S621-RAF1 G370R [cytosol] (R-HSA-9656094) p-S621-RAF1 D486G [cytosol] (R-HSA-9656085) p-S621-RAF1 T491R [cytosol] (R-HSA-9656145) p-S338,Y341,T492,S494,S621 RAF1 D486N [cytosol] (R-HSA-9656026) p-S338,Y341,T492,S494,S621 RAF1 S427G [cytosol] (R-HSA-9656070) p-S338,Y341,T492,S494,S621 RAF1 L613V [cytosol] (R-HSA-9656035) p-S338,Y341,S494,S621-RAF1 T491I [cytosol] (R-HSA-9656019) p-S338,Y341,T492,S494,S621 RAF1 G361A [cytosol] (R-HSA-9656029) p-S338,Y341,T492,S494,S621 RAF1 G370R [cytosol] (R-HSA-9656031) p-S338,Y341,T492,S494,S621 RAF1 D486G [cytosol] (R-HSA-9656023) p-S338,Y341,S494,S621 RAF1 T491R [cytosol] (R-HSA-9656017) p-S338,Y341,T492,S494,S621 RAF1 S259F [cytosol] (R-HSA-9656062) p-S338,Y341,T492,S494,S621 RAF1 P261A [cytosol] (R-HSA-9656041) p-S338,Y341,T492,S494,S621 RAF1 S257L [cytosol] (R-HSA-9656058) p-S338,Y341,T492,S494,S621 RAF1 P261L [cytosol] (R-HSA-9656043) p-S338,Y341,T492,S494,S621 RAF1 P261T [cytosol] (R-HSA-9656053) p-S338,Y341,T492,S494,S621 RAF1 N262K [cytosol] (R-HSA-9656037) p-S338,Y341,T492,S494,S621 RAF1 P261S [cytosol] (R-HSA-9656050) p-S338,Y341,T492,S494,S621 RAF1 S259T [cytosol] (R-HSA-9656067) p-S338,Y341,T492,S494,S621 RAF1 T260R [cytosol] (R-HSA-9656077) p-S338,Y341,T492,S494,S621 RAF1 P261R [cytosol] (R-HSA-9656047) p-S338,Y341,T492,S494,S621 RAF1 R256S [cytosol] (R-HSA-9656056) p-S338,Y341,T492,S494,S621 RAF1 T260I [cytosol] (R-HSA-9656074) p-S338,Y341,T492,S494,S621 RAF1 V263A [cytosol] (R-HSA-9656080) p-S338,Y341,T492,S494,S621 RAF1 S259P [cytosol] (R-HSA-9656065) RAF1 [cytosol] (R-HSA-167205) p-S338,Y340,Y341-RAF1 [cytosol] (R-HSA-5624465) p-S338-RAF1 [cytosol] (R-HSA-5624469) p-S621-RAF1 [plasma membrane] (R-HSA-206222) p-Y341,T491,S494,S621 RAF1 [plasma membrane] (R-HSA-5675420) p-S259,S621-RAF1 [cytosol] (R-HSA-109786) hyperphosphorylated RAF1 [plasma membrane] (R-HSA-5675193) p-S621-RAF1 [cytosol] (R-HSA-206028) p-S338,Y341,T491,S494,S621 RAF1 [plasma membrane] (R-HSA-5672665) p-S338,Y341,T491,S494,S621 RAF1 [cytosol] (R-HSA-5672664)	0.499	2

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