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Jag1 binds Notch2

Stable Identifier
R-MMU-2032378
Type
Reaction
Species
Mus musculus
Compartment
Summation

Mouse Jag1 exogenously expressed on the surface of Chinese hamster ovary (CHO) cells binds Notch2, a predominant Notch protein on the surface of mouse BaF3 cells, inducing Notch2 cleavage and translocation of Notch2 intracellular domain (NICD2) to the nucleus.

Participants
Orthologous Events