Jag2 binds Notch2

Stable Identifier
R-MMU-2032379
Type
Reaction
Species
Mus musculus
Compartment
Summation

Mouse Jag2 exogenously expressed on the surface of Chinese hamster ovary (CHO) cells binds Notch2, a predominant Notch protein on the surface of mouse BaF3 cells, inducing Notch2 cleavage and translocation of Notch2 intracellular domain (NICD2) to the nucleus (Shimizu et al. 2000).

Participants
Orthologous Events
Authored
Reviewed