Reactome: A Curated Pathway Database

Dll1 binds Notch2

Stable Identifier
R-MMU-2060798
Type
Reaction
Species
Mus musculus
Compartment
Summation

Mouse Dll1 exogenously expressed on the surface of Chinese hamster ovary (CHO) cells binds Notch2, a predominant Notch protein on the surface of mouse BaF3 cells, inducing Notch2 cleavage and translocation of Notch2 intracellular domain (NICD2) to the nucleus (Shimizu et al. 2000).

Literature References
Participants
Orthologous Events