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Rbbp7 [nucleoplasm]
Stable Identifier
R-MMU-212227
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
nucleoplasm
Synonyms
RBBP7, Q60973
Locations in the PathwayBrowser
Expand all
Cell Cycle (Mus musculus)
Chromosome Maintenance (Mus musculus)
Nucleosome assembly (Mus musculus)
Deposition of new CENPA-containing nucleosomes at the centromere (Mus musculus)
HJURP:CENPA complex localizes to the centromere (Mus musculus)
CCAN:DNA:CASC5:Mis18 complex:HJURP complex:CENPA:H4 [nucleoplasm] (Mus musculus)
HJURP:NPM1:RBBP4:RBBP7:RUVBL1:CENPA:H4 [nucleoplasm] (Mus musculus)
Rbbp7 [nucleoplasm] (Mus musculus)
HJURP:NPM1:RBBP4:RBBP7:RUVBL1:CENPA:H4 [nucleoplasm] (Mus musculus)
Rbbp7 [nucleoplasm] (Mus musculus)
RSF complex binds the centromere (Mus musculus)
CCAN:DNA:CASC5:Mis18 complex:HJURP complex:CENPA nucleosome [nucleoplasm] (Mus musculus)
HJURP:NPM1:RBBP4:RBBP7:RUVBL1 [nucleoplasm] (Mus musculus)
Rbbp7 [nucleoplasm] (Mus musculus)
HJURP:NPM1:RBBP4:RBBP7:RUVBL1 [nucleoplasm] (Mus musculus)
Rbbp7 [nucleoplasm] (Mus musculus)
Cellular responses to external stimuli (Mus musculus)
Cellular responses to stress (Mus musculus)
Cellular Senescence (Mus musculus)
Oxidative Stress Induced Senescence (Mus musculus)
Formation of PRC2-EZH2 complex (Mus musculus)
PRC2 (EZH2) Core [nucleoplasm] (Mus musculus)
RBBP4,7 [nucleoplasm] (Mus musculus)
Rbbp7 [nucleoplasm] (Mus musculus)
Rbbp7 [nucleoplasm] (Mus musculus)
Chromatin organization (Mus musculus)
Chromatin modifying enzymes (Mus musculus)
HATs acetylate histones (Mus musculus)
Type B histone acetlytransferase complex acetylates histone H4 (Mus musculus)
HAT1:RBBP7 [nucleoplasm] (Mus musculus)
Rbbp7 [nucleoplasm] (Mus musculus)
HDACs deacetylate histones (Mus musculus)
HDAC1:2-containing complex binds HDAC2 Inhibitors (Mus musculus)
HDAC1:2-containing complex [nucleoplasm] (Mus musculus)
NuRD complex [nucleoplasm] (Mus musculus)
Rbbp7 [nucleoplasm] (Mus musculus)
Sin3A complex [nucleoplasm] (Mus musculus)
Sin3a core complex [nucleoplasm] (Mus musculus)
Rbbp7 [nucleoplasm] (Mus musculus)
HDAC1:2-containing complex:HDAC2 inhibitors [nucleoplasm] (Mus musculus)
HDAC1:2-containing complex [nucleoplasm] (Mus musculus)
NuRD complex [nucleoplasm] (Mus musculus)
Rbbp7 [nucleoplasm] (Mus musculus)
Sin3A complex [nucleoplasm] (Mus musculus)
Sin3a core complex [nucleoplasm] (Mus musculus)
Rbbp7 [nucleoplasm] (Mus musculus)
HDAC1:2-containing complex deacetylate histones (Mus musculus)
HDAC1:2-containing complex [nucleoplasm] (Mus musculus)
NuRD complex [nucleoplasm] (Mus musculus)
Rbbp7 [nucleoplasm] (Mus musculus)
Sin3A complex [nucleoplasm] (Mus musculus)
Sin3a core complex [nucleoplasm] (Mus musculus)
Rbbp7 [nucleoplasm] (Mus musculus)
HDAC1:2-containing complex:HDAC2 inhibitors [nucleoplasm] (Mus musculus)
HDAC1:2-containing complex [nucleoplasm] (Mus musculus)
NuRD complex [nucleoplasm] (Mus musculus)
Rbbp7 [nucleoplasm] (Mus musculus)
Sin3A complex [nucleoplasm] (Mus musculus)
Sin3a core complex [nucleoplasm] (Mus musculus)
Rbbp7 [nucleoplasm] (Mus musculus)
PKMTs methylate histone lysines (Mus musculus)
PRC2 (EZH2) Core:AEBP2 methylates lysine-28 of histone H3 (H3K27) (Mus musculus)
PRC2 (EZH2) Core:AEBP2 [nucleoplasm] (Mus musculus)
PRC2 (EZH2) Core [nucleoplasm] (Mus musculus)
RBBP4,7 [nucleoplasm] (Mus musculus)
Rbbp7 [nucleoplasm] (Mus musculus)
RMTs methylate histone arginines (Mus musculus)
RBBP7 binds histone H3 (Mus musculus)
RBBP7:Replicative histone H3 [nucleoplasm] (Mus musculus)
Rbbp7 [nucleoplasm] (Mus musculus)
Rbbp7 [nucleoplasm] (Mus musculus)
Gene expression (Transcription) (Mus musculus)
Epigenetic regulation of gene expression (Mus musculus)
PRC2 methylates histones and DNA (Mus musculus)
DNMT1,3A,3B:PRC2 methylates cytosine and histone H3 (Mus musculus)
DNMT1,3A,3B:PRC2:Chromatin (5-mC, H3K27me3) [nucleoplasm] (Mus musculus)
PRC2:Chromatin (5-methylcytosine, H3K27me3) [nucleoplasm] (Mus musculus)
PRC2 (EZH2) Core [nucleoplasm] (Mus musculus)
RBBP4,7 [nucleoplasm] (Mus musculus)
Rbbp7 [nucleoplasm] (Mus musculus)
DNMT1,3A,3B:PRC2:Chromatin [nucleoplasm] (Mus musculus)
PRC2 Core:Chromatin [nucleoplasm] (Mus musculus)
PRC2 (EZH2) Core [nucleoplasm] (Mus musculus)
RBBP4,7 [nucleoplasm] (Mus musculus)
Rbbp7 [nucleoplasm] (Mus musculus)
PRC2 recruits DNA methyltransferases (Mus musculus)
DNMT1,3A,3B:PRC2:Chromatin [nucleoplasm] (Mus musculus)
PRC2 Core:Chromatin [nucleoplasm] (Mus musculus)
PRC2 (EZH2) Core [nucleoplasm] (Mus musculus)
RBBP4,7 [nucleoplasm] (Mus musculus)
Rbbp7 [nucleoplasm] (Mus musculus)
PRC2 Core:Chromatin [nucleoplasm] (Mus musculus)
PRC2 (EZH2) Core [nucleoplasm] (Mus musculus)
RBBP4,7 [nucleoplasm] (Mus musculus)
Rbbp7 [nucleoplasm] (Mus musculus)
PRC2 trimethylates histone H3 at lysine-27 (Mus musculus)
PRC2:Chromatin (H3K27me3) [nucleoplasm] (Mus musculus)
PRC2 [nucleoplasm] (Mus musculus)
PRC2 (EZH2) Core [nucleoplasm] (Mus musculus)
RBBP4,7 [nucleoplasm] (Mus musculus)
Rbbp7 [nucleoplasm] (Mus musculus)
PRC2 (EZH2) Core:AEBP2 [nucleoplasm] (Mus musculus)
PRC2 (EZH2) Core [nucleoplasm] (Mus musculus)
RBBP4,7 [nucleoplasm] (Mus musculus)
Rbbp7 [nucleoplasm] (Mus musculus)
PRC2:JARID2:MTF2 [nucleoplasm] (Mus musculus)
PRC2 (EZH2) Core [nucleoplasm] (Mus musculus)
RBBP4,7 [nucleoplasm] (Mus musculus)
Rbbp7 [nucleoplasm] (Mus musculus)
PRC2:PHF1 [nucleoplasm] (Mus musculus)
PRC2 (EZH2) Core [nucleoplasm] (Mus musculus)
RBBP4,7 [nucleoplasm] (Mus musculus)
Rbbp7 [nucleoplasm] (Mus musculus)
PRC2:PHF19 [nucleoplasm] (Mus musculus)
PRC2 (EZH2) Core [nucleoplasm] (Mus musculus)
RBBP4,7 [nucleoplasm] (Mus musculus)
Rbbp7 [nucleoplasm] (Mus musculus)
PRC2:Chromatin [nucleoplasm] (Mus musculus)
PRC2 [nucleoplasm] (Mus musculus)
PRC2 (EZH2) Core [nucleoplasm] (Mus musculus)
RBBP4,7 [nucleoplasm] (Mus musculus)
Rbbp7 [nucleoplasm] (Mus musculus)
PRC2 (EZH2) Core:AEBP2 [nucleoplasm] (Mus musculus)
PRC2 (EZH2) Core [nucleoplasm] (Mus musculus)
RBBP4,7 [nucleoplasm] (Mus musculus)
Rbbp7 [nucleoplasm] (Mus musculus)
PRC2:JARID2:MTF2 [nucleoplasm] (Mus musculus)
PRC2 (EZH2) Core [nucleoplasm] (Mus musculus)
RBBP4,7 [nucleoplasm] (Mus musculus)
Rbbp7 [nucleoplasm] (Mus musculus)
PRC2:PHF1 [nucleoplasm] (Mus musculus)
PRC2 (EZH2) Core [nucleoplasm] (Mus musculus)
RBBP4,7 [nucleoplasm] (Mus musculus)
Rbbp7 [nucleoplasm] (Mus musculus)
PRC2:PHF19 [nucleoplasm] (Mus musculus)
PRC2 (EZH2) Core [nucleoplasm] (Mus musculus)
RBBP4,7 [nucleoplasm] (Mus musculus)
Rbbp7 [nucleoplasm] (Mus musculus)
RNA Polymerase I Transcription (Mus musculus)
RNA Polymerase I Promoter Clearance (Mus musculus)
RNA Polymerase I Transcription Initiation (Mus musculus)
Recruitment of Acetylated SL1 to phosUBF-1:rDNA Promoter (Mus musculus)
TTF-I:Sal Box:CSB:G9a:NuRD [nucleoplasm] (Mus musculus)
NuRD complex [nucleoplasm] (Mus musculus)
Rbbp7 [nucleoplasm] (Mus musculus)
RNA Polymerase II Transcription (Mus musculus)
Generic Transcription Pathway (Mus musculus)
Transcriptional Regulation by E2F6 (Mus musculus)
E2F6:TFDP1:EPC1 binds the PRC2 complex (Mus musculus)
E2F6:TFDP1:EPC1:PRC2 (EZH2) core [nucleoplasm] (Mus musculus)
PRC2 (EZH2) Core [nucleoplasm] (Mus musculus)
RBBP4,7 [nucleoplasm] (Mus musculus)
Rbbp7 [nucleoplasm] (Mus musculus)
PRC2 (EZH2) Core [nucleoplasm] (Mus musculus)
RBBP4,7 [nucleoplasm] (Mus musculus)
Rbbp7 [nucleoplasm] (Mus musculus)
Transcriptional Regulation by TP53 (Mus musculus)
Regulation of TP53 Activity (Mus musculus)
Regulation of TP53 Activity through Acetylation (Mus musculus)
MTA2-NuRD complex deacetylates TP53 (Mus musculus)
MTA2-NuRD complex [nucleoplasm] (Mus musculus)
Rbbp7 [nucleoplasm] (Mus musculus)
Metabolism of proteins (Mus musculus)
Post-translational protein modification (Mus musculus)
Neddylation (Mus musculus)
AcM-UBE2M transfers NEDD8 to CRL4 E3 ubiquitin ligase complex (Mus musculus)
NEDD8-AcM-UBE2M:CRL4 E3 ubiquitin ligase:COMMDs:CCDC22:DCUND1,2,4,5 [nucleoplasm] (Mus musculus)
CRL4 E3 ubiquitin ligase:COMMDs:CCDC22 [nucleoplasm] (Mus musculus)
RBX1:CUL4:DDB1:DCAFs [nucleoplasm] (Mus musculus)
DCAF protein [nucleoplasm] (Mus musculus)
Rbbp7 [nucleoplasm] (Mus musculus)
NEDD8-CRL4 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [nucleoplasm] (Mus musculus)
NEDD8-CRL4 E3 ligase complex [nucleoplasm] (Mus musculus)
DCAF protein [nucleoplasm] (Mus musculus)
Rbbp7 [nucleoplasm] (Mus musculus)
CAND1 binds CRL4 E3 ubiquitin ligase in the nucleus (Mus musculus)
CRL4 E3 ubiquitin ligase:CAND1 [nucleoplasm] (Mus musculus)
RBX1:CUL4:DDB1:DCAFs [nucleoplasm] (Mus musculus)
DCAF protein [nucleoplasm] (Mus musculus)
Rbbp7 [nucleoplasm] (Mus musculus)
RBX1:CUL4:DDB1:DCAFs [nucleoplasm] (Mus musculus)
DCAF protein [nucleoplasm] (Mus musculus)
Rbbp7 [nucleoplasm] (Mus musculus)
COMMDs displace CAND1 from CRL4 E3 ubiquitin ligase complex (Mus musculus)
CRL4 E3 ubiquitin ligase:CAND1 [nucleoplasm] (Mus musculus)
RBX1:CUL4:DDB1:DCAFs [nucleoplasm] (Mus musculus)
DCAF protein [nucleoplasm] (Mus musculus)
Rbbp7 [nucleoplasm] (Mus musculus)
CRL4 E3 ubiquitin ligase:COMMDs:CCDC22 [nucleoplasm] (Mus musculus)
RBX1:CUL4:DDB1:DCAFs [nucleoplasm] (Mus musculus)
DCAF protein [nucleoplasm] (Mus musculus)
Rbbp7 [nucleoplasm] (Mus musculus)
COP9 signalosome deneddylates nuclear CRL4 E3 ubiquitin ligase complex (Mus musculus)
CRL4 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [nucleoplasm] (Mus musculus)
RBX1:CUL4:DDB1:DCAFs [nucleoplasm] (Mus musculus)
DCAF protein [nucleoplasm] (Mus musculus)
Rbbp7 [nucleoplasm] (Mus musculus)
NEDD8-CRL4 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [nucleoplasm] (Mus musculus)
NEDD8-CRL4 E3 ligase complex [nucleoplasm] (Mus musculus)
DCAF protein [nucleoplasm] (Mus musculus)
Rbbp7 [nucleoplasm] (Mus musculus)
NEDD8:AcM-UBE2M binds CRL4 E3 ubiquitin ligase complex (Mus musculus)
CRL4 E3 ubiquitin ligase:COMMDs:CCDC22 [nucleoplasm] (Mus musculus)
RBX1:CUL4:DDB1:DCAFs [nucleoplasm] (Mus musculus)
DCAF protein [nucleoplasm] (Mus musculus)
Rbbp7 [nucleoplasm] (Mus musculus)
NEDD8-AcM-UBE2M:CRL4 E3 ubiquitin ligase:COMMDs:CCDC22:DCUND1,2,4,5 [nucleoplasm] (Mus musculus)
CRL4 E3 ubiquitin ligase:COMMDs:CCDC22 [nucleoplasm] (Mus musculus)
RBX1:CUL4:DDB1:DCAFs [nucleoplasm] (Mus musculus)
DCAF protein [nucleoplasm] (Mus musculus)
Rbbp7 [nucleoplasm] (Mus musculus)
Signal Transduction (Mus musculus)
Intracellular signaling by second messengers (Mus musculus)
PIP3 activates AKT signaling (Mus musculus)
PTEN Regulation (Mus musculus)
Regulation of PTEN gene transcription (Mus musculus)
MECOM (EVI1) recruits polycomb repressor complexes (PRCs) to the PTEN gene promoter (Mus musculus)
MECOM:(PRC1.4,PRC2 (EZH2) core):PTEN gene [nucleoplasm] (Mus musculus)
MECOM:(PRC1.4,PRC2 (EZH2) core) [nucleoplasm] (Mus musculus)
PRC1.4,PRC2 (EZH2) core [nucleoplasm] (Mus musculus)
PRC2 (EZH2) Core [nucleoplasm] (Mus musculus)
RBBP4,7 [nucleoplasm] (Mus musculus)
Rbbp7 [nucleoplasm] (Mus musculus)
PRC1.4,PRC2 (EZH2) core [nucleoplasm] (Mus musculus)
PRC2 (EZH2) Core [nucleoplasm] (Mus musculus)
RBBP4,7 [nucleoplasm] (Mus musculus)
Rbbp7 [nucleoplasm] (Mus musculus)
SALL4 recruits NuRD to PTEN gene (Mus musculus)
NuRD complex [nucleoplasm] (Mus musculus)
Rbbp7 [nucleoplasm] (Mus musculus)
SALL4:NuRD:PTEN gene [nucleoplasm] (Mus musculus)
SALL4:NuRD [nucleoplasm] (Mus musculus)
NuRD complex [nucleoplasm] (Mus musculus)
Rbbp7 [nucleoplasm] (Mus musculus)
External Reference Information
External Reference
UniProt:Q60973 Rbbp7
Gene Names
Rbbp7, Rbap46
Chain
initiator methionine:1, chain:2-425
Reference Genes
BioGPS Gene:245688 Rbbp7
ENSEMBL:ENSMUSG00000031353 Rbbp7
KEGG Gene (Mus musculus):245688 Rbbp7
Monarch:245688 Rbbp7
NCBI Gene:245688 Rbbp7
UCSC:Q60973 Rbbp7
Reference Transcript
RefSeq:NM_009031.3 Rbbp7
Other Identifiers
10602164
10603011
1415775_at
1456227_x_at
17539415
245688
4418526
4463405
4643755
4655278
4791481
4795958
4817692
4906480
5026618
5053062
5246933
5250810
5533574
5555029
5581835
93081_at
A_51_P114385
A_55_P2080542
A_55_P2123822
GE1532312
GE33544
GO:0000122
GO:0000228
GO:0003674
GO:0003723
GO:0005515
GO:0005575
GO:0005622
GO:0005634
GO:0005654
GO:0005694
GO:0005737
GO:0005829
GO:0006260
GO:0006325
GO:0006338
GO:0006950
GO:0008150
GO:0009058
GO:0016581
GO:0030308
GO:0032991
GO:0034641
GO:0035098
GO:0040007
GO:0043226
GO:0045892
GO:0048545
GO:0051276
GO:0070370
ILMN_1219275
ILMN_1243578
ILMN_2691187
ILMN_2691192
ILMN_2896823
Msa.1702.0_f_at
Msa.34515.0_s_at
U35142_f_at
mMC020249
mMC023105
mMR031174
Participant Of
hasMember
DCAF protein [nucleoplasm]
RBBP4,7 [nucleoplasm]
hasComponent
HAT1:RBBP7 [nucleoplasm]
HJURP:NPM1:RBBP4:RBBP7:RUVBL1 [nucleoplasm]
HJURP:NPM1:RBBP4:RBBP7:RUVBL1:CENPA:H4 [nucleoplasm]
MTA2-NuRD complex [nucleoplasm]
NuRD complex [nucleoplasm]
RBBP7:Replicative histone H3 [nucleoplasm]
Sin3a core complex [nucleoplasm]
input
Formation of PRC2-EZH2 complex
RBBP7 binds histone H3
Other forms of this molecule
Rbbp7 [nucleoplasm]
Inferred From
RBBP7 [nucleoplasm] (Homo sapiens)
Cross References
RefSeq
NP_033057.3
Ensembl
ENSMUST00000033720
,
ENSMUSP00000033720
,
ENSMUSG00000031353
PRO
Q60973
MGI
1194910
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q60I23 Q60I23
0.462
2
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