Sec-tRNA(Sec) binds to Eefsec:GTP

Stable Identifier
R-MMU-2408515
Type
Reaction [binding]
Species
Mus musculus
Compartment
cytosol
ReviewStatus
5/5
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Sec-tRNA(Sec) binds to Eefsec:GTP
The final product, selenocysteinyl transfer RNA (tRNA) for Sec (Sec-tRNASec) binds to selenocysteine-specific elongation factor (Eefsec) aka Selb complexed with GTP (Tujebajeva et al. 2004, Fagegaltier et al. 2000). This complex is now ready to be delivered to the 80S ribosome.
Literature References
PubMed ID Title Journal Year
11265756 Decoding apparatus for eukaryotic selenocysteine insertion

Tujebajeva, RM, Copeland, PR, Xu, XM, Carlson, BA, Harney, JW, Driscoll, DM, Hatfield, DL, Berry, MJ

EMBO Rep. 2000
10970870 Characterization of mSelB, a novel mammalian elongation factor for selenoprotein translation

Fagegaltier, D, Hubert, N, Yamada, K, Mizutani, T, Carbon, P, Krol, A

EMBO J. 2000
Participants
Input
Output
Orthologous Events
Sec-tRNA(Sec) binds to EEFSEC:GTP (Homo sapiens)
Authored
Williams, MG  (2014-05-06)
Reviewed
Rush, MG  (2015-08-30)
Created
Williams, MG  (2012-07-17)
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