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Lep:p-Lepr:p-Jak2 [plasma membrane]
Stable Identifier
R-MMU-2586540
Type
Complex
Species
Mus musculus
Compartment
plasma membrane
Participants
components
x 2
Leptin [extracellular region]
(Mus musculus)
p-Lepr:p-Jak2 [plasma membrane]
(Mus musculus)
Participates
as a component of
Lep:p-Lepr:p-Jak2:p-Shp2 [plasma membrane] (Mus musculus)
Lep:p-Lepr:p-Jak2:p-Stat3 [plasma membrane] (Mus musculus)
Lep:p-Lepr:p-Jak2:p-Stat5 [plasma membrane] (Mus musculus)
Lep:p-Lepr:p-Jak2:Sh2b1 [plasma membrane] (Mus musculus)
Lep:p-Lepr:p-Jak2:Sh2b1:Irs1,2 [plasma membrane] (Mus musculus)
Lep:p-Lepr:p-Jak2:Sh2b1:p-Irs1,2 [plasma membrane] (Mus musculus)
Lep:p-Lepr:p-Jak2:Shp2 [plasma membrane] (Mus musculus)
Lep:p-Lepr:p-Jak2:Socs3 [plasma membrane] (Mus musculus)
Lep:p-Lepr:p-Jak2:Stat3 [plasma membrane] (Mus musculus)
Lep:p-Lepr:p-Jak2:Stat5 [plasma membrane] (Mus musculus)
as an input of
Phosphoryated Lep:Lepr:Jak2 Binds Sh2b1 (Mus musculus)
Phosphorylated Lepr Binds Shp2 (Mus musculus)
Phosphorylated Lepr Binds Socs3 (Mus musculus)
Phosphorylated Lepr Binds Stat3 (Mus musculus)
Phosphorylated Lepr Binds Stat5 (Mus musculus)
as an output of
Jak2 Phosphorylates Lepr (Mus musculus)
Phosphorylated Stat3 Dissociates from Leptin Receptor (Mus musculus)
Phosphorylated Stat5 Dissociates from Leptin Receptor (Mus musculus)
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