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Lep:p-Lepr:p-Jak2 [plasma membrane]
Stable Identifier
R-MMU-2586540
Type
Complex
Species
Mus musculus
Compartment
plasma membrane
Participants
components
2 x
Leptin [extracellular region] (Mus musculus)
p-Lepr:p-Jak2 [plasma membrane] (Mus musculus)
Participant Of
hasComponent
Lep:p-Lepr:p-Jak2:p-Shp2 [plasma membrane]
Lep:p-Lepr:p-Jak2:p-Stat3 [plasma membrane]
Lep:p-Lepr:p-Jak2:p-Stat5 [plasma membrane]
Lep:p-Lepr:p-Jak2:Sh2b1 [plasma membrane]
Lep:p-Lepr:p-Jak2:Sh2b1:Irs1,2 [plasma membrane]
Lep:p-Lepr:p-Jak2:Sh2b1:p-Irs1,2 [plasma membrane]
Lep:p-Lepr:p-Jak2:Shp2 [plasma membrane]
Lep:p-Lepr:p-Jak2:Socs3 [plasma membrane]
Lep:p-Lepr:p-Jak2:Stat3 [plasma membrane]
Lep:p-Lepr:p-Jak2:Stat5 [plasma membrane]
input
Phosphoryated Lep:Lepr:Jak2 Binds Sh2b1
Phosphorylated Lepr Binds Shp2
Phosphorylated Lepr Binds Socs3
Phosphorylated Lepr Binds Stat3
Phosphorylated Lepr Binds Stat5
output
Jak2 Phosphorylates Lepr
Phosphorylated Stat3 Dissociates from Leptin Receptor
Phosphorylated Stat5 Dissociates from Leptin Receptor
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