Jak2 Phosphorylates Lepr

Stable Identifier
R-MMU-2586557
Type
Reaction [transition]
Species
Mus musculus
Compartment
General
SVG |   | PPTX  | SBGN
Jak2 Phosphorylates Lepr

Jak2 phosphorylates Lepr at multiple tyrosine residues, including at least Tyr-985, Tyr-1077, and Tyr-1138.

Literature References
PubMed ID Title Journal Year
10449753 Leptin receptor activation of SH2 domain containing protein tyrosine phosphatase 2 modulates Ob receptor signal transduction

Li, C, Friedman, JM

Proc. Natl. Acad. Sci. U.S.A. 1999
11108838 Identification of the Y985 and Y1077 motifs as SOCS3 recruitment sites in the murine leptin receptor

Eyckerman, S, Broekaert, D, Verhee, A, Vandekerckhove, J, Tavernier, J

FEBS Lett. 2000
Participants
Catalyst Activity
Catalyst Activity
Title
protein tyrosine kinase activity of Lep:Lepr:p-Jak2 [plasma membrane]
Physical Entity
Activity
Orthologous Events
Authored
Reviewed
Created
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