Phosphorylated Stat3 Dimer Translocates to the Nucleus

Stable Identifier
R-MMU-2730598
Type
Reaction [BlackBoxEvent]
Species
Mus musculus
Compartment
Locations in the PathwayBrowser
Summation

Stat3 dimers are imported into the nucleus by the importin alpha/beta pathway. Stat3 constitutively shuttles into and out of the nucleus. The unphosphorylated form is predominantly cytosolic. Phosphorylation of Stat3 shifts the distribution from the cytosol to the nucleus.

Participants
Participant Of
Orthologous Events