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TRIO [cytosol]
Stable Identifier
R-MMU-2980605
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
cytosol
Synonyms
Q0KL02
Locations in the PathwayBrowser
Expand all
Developmental Biology (Mus musculus)
Nervous system development (Mus musculus)
Axon guidance (Mus musculus)
Netrin-1 signaling (Mus musculus)
DCC mediated attractive signaling (Mus musculus)
Activation of Cdc42 (Mus musculus)
DOCK1,TRIO [cytosol] (Mus musculus)
TRIO [cytosol] (Mus musculus)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO [plasma membrane] (Mus musculus)
DOCK1,TRIO [cytosol] (Mus musculus)
TRIO [cytosol] (Mus musculus)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO:CDC42:GTP [plasma membrane] (Mus musculus)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO [plasma membrane] (Mus musculus)
DOCK1,TRIO [cytosol] (Mus musculus)
TRIO [cytosol] (Mus musculus)
Activation of Rac1 (Mus musculus)
DOCK1,TRIO [cytosol] (Mus musculus)
TRIO [cytosol] (Mus musculus)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO [plasma membrane] (Mus musculus)
DOCK1,TRIO [cytosol] (Mus musculus)
TRIO [cytosol] (Mus musculus)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO:RAC1:GTP [plasma membrane] (Mus musculus)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO [plasma membrane] (Mus musculus)
DOCK1,TRIO [cytosol] (Mus musculus)
TRIO [cytosol] (Mus musculus)
RhoGTPase GEF's recruited to DCC (Mus musculus)
DOCK1,TRIO [cytosol] (Mus musculus)
TRIO [cytosol] (Mus musculus)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO [plasma membrane] (Mus musculus)
DOCK1,TRIO [cytosol] (Mus musculus)
TRIO [cytosol] (Mus musculus)
Signal Transduction (Mus musculus)
Death Receptor Signaling (Mus musculus)
p75 NTR receptor-mediated signalling (Mus musculus)
Cell death signalling via NRAGE, NRIF and NADE (Mus musculus)
NRAGE signals death through JNK (Mus musculus)
p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor (Mus musculus)
GEFs [cytosol] (Mus musculus)
TRIO [cytosol] (Mus musculus)
Signaling by GPCR (Mus musculus)
GPCR downstream signalling (Mus musculus)
G alpha (12/13) signalling events (Mus musculus)
GEFs activate RhoA,B,C (Mus musculus)
GEFs [cytosol] (Mus musculus)
TRIO [cytosol] (Mus musculus)
G alpha (q) signalling events (Mus musculus)
G alpha (q) binds to Trio family RhoGEFs (Mus musculus)
G-protein alpha (q/11):Trio family RhoGEFs [plasma membrane] (Mus musculus)
TRIO family RhoGEFs [cytosol] (Mus musculus)
TRIO [cytosol] (Mus musculus)
TRIO family RhoGEFs [cytosol] (Mus musculus)
TRIO [cytosol] (Mus musculus)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Mus musculus)
Signaling by Rho GTPases (Mus musculus)
RHO GTPase cycle (Mus musculus)
CDC42 GTPase cycle (Mus musculus)
CDC42 GEFs activate CDC42 (Mus musculus)
CDC42 GEFs [cytosol] (Mus musculus)
TRIO [cytosol] (Mus musculus)
RAC1 GTPase cycle (Mus musculus)
RAC1 GEFs activate RAC1 (Mus musculus)
RAC1 GEFs [cytosol] (Mus musculus)
TRIO [cytosol] (Mus musculus)
RAC2 GTPase cycle (Mus musculus)
RAC2 GEFs activate RAC2 (Mus musculus)
RAC2 GEFs [cytosol] (Mus musculus)
TRIO [cytosol] (Mus musculus)
RAC3 GTPase cycle (Mus musculus)
RAC3 GEFs activate RAC3 (Mus musculus)
RAC3 GEFs [cytosol] (Mus musculus)
TRIO [cytosol] (Mus musculus)
RHOA GTPase cycle (Mus musculus)
RHOA GEFs activate RHOA (Mus musculus)
RHOA GEFs [cytosol] (Mus musculus)
TRIO [cytosol] (Mus musculus)
RHOG GTPase cycle (Mus musculus)
RHOG GEFs activate RHOG (Mus musculus)
RHOG GEFs [cytosol] (Mus musculus)
TRIO [cytosol] (Mus musculus)
RHOJ GTPase cycle (Mus musculus)
RHOJ GEFs activate RHOJ (Mus musculus)
RHOJ GEFs [cytosol] (Mus musculus)
TRIO [cytosol] (Mus musculus)
External Reference Information
External Reference
UniProt:Q0KL02
Reference Genes
BioGPS Gene:223435
ENSEMBL:ENSMUSG00000022263
ENSEMBL:ENSMUSG00000022263.11
KEGG Gene (Mus musculus):223435
Monarch:223435
NCBI Gene:223435
UCSC:Q0KL02
Reference Transcript
RefSeq:NM_001081302.1
RefSeq:XM_006520054.3
Other Identifiers
104053_at
10427928
10427991
108502_at
1433745_at
1438099_at
1454711_at
17316207
223435
4375833
4390308
4392038
4395162
4400077
4423563
4466515
4471467
4474082
4544103
4544376
4559110
4567358
4598222
4614114
4620395
4623367
4627195
4657239
4675056
4705950
4769954
4821347
4825416
4843568
4876567
4876675
4934592
4955019
4963871
4969211
5020693
5092239
5108797
5137914
5153971
5165585
5170281
5175151
5179311
5182128
5201395
5219455
5257359
5264354
5277827
5283270
5319764
5345974
5388673
5402740
5403570
5420754
5467623
5475610
5477847
5484024
5491500
5492484
5493040
5515206
5524237
5525527
5526562
5534029
5534486
5555324
5570363
5574379
5584041
A_52_P521507
A_55_P2006861
A_55_P2165314
A_66_P136767
GE102314
GO:0000166
GO:0003824
GO:0004672
GO:0004674
GO:0005085
GO:0005515
GO:0005524
GO:0005737
GO:0005768
GO:0005769
GO:0006468
GO:0007411
GO:0016301
GO:0016310
GO:0016740
GO:0019898
GO:0019899
GO:0023052
GO:0030154
GO:0031410
GO:0036211
GO:0042995
GO:0043226
GO:0045599
GO:0048786
GO:0048812
GO:0048856
GO:0050804
GO:0098685
GO:0098772
GO:0098794
GO:0098978
GO:0099170
GO:0106310
GO:0140096
ILMN_1226918
ILMN_2491741
ILMN_2522750
aa185921_s_at
mMC024633
Participates
as a member of
RHOA GEFs [cytosol] (Mus musculus)
RAC2 GEFs [cytosol] (Mus musculus)
RAC1 GEFs [cytosol] (Mus musculus)
RHOG GEFs [cytosol] (Mus musculus)
RAC3 GEFs [cytosol] (Mus musculus)
TRIO family RhoGEFs [cytosol] (Mus musculus)
GEFs [cytosol] (Mus musculus)
DOCK1,TRIO [cytosol] (Mus musculus)
as a candidate of
CDC42 GEFs [cytosol] (Mus musculus)
RHOJ GEFs [cytosol] (Mus musculus)
Inferred From
TRIO [cytosol]
(Homo sapiens)
Cross References
RefSeq
XP_006520117.1
,
NP_001074771.1
IntEnz
2.7.11.1
Ensembl
ENSMUSP00000087714
,
ENSMUSG00000022263
,
ENSMUST00000090247
PRO
Q0KL02
MGI
1927230
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