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KALRN [cytosol]
Stable Identifier
R-MMU-3006505
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
cytosol
Synonyms
A2CG49
Locations in the PathwayBrowser
Expand all
Developmental Biology (Mus musculus)
Nervous system development (Mus musculus)
Axon guidance (Mus musculus)
EPH-Ephrin signaling (Mus musculus)
EPHB-mediated forward signaling (Mus musculus)
EPHB2 binds KALRN (Mus musculus)
EFNBs:p-EPHBs:KALRN [plasma membrane] (Mus musculus)
KALRN [cytosol] (Mus musculus)
KALRN [cytosol] (Mus musculus)
KALRN exchanges GTP for GDP on RAC1, activating it (Mus musculus)
EFNBs:p-EPHBs:KALRN [plasma membrane] (Mus musculus)
KALRN [cytosol] (Mus musculus)
KALRN [cytosol] (Mus musculus)
Signal Transduction (Mus musculus)
Death Receptor Signaling (Mus musculus)
p75 NTR receptor-mediated signalling (Mus musculus)
Cell death signalling via NRAGE, NRIF and NADE (Mus musculus)
NRAGE signals death through JNK (Mus musculus)
p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor (Mus musculus)
GEFs [cytosol] (Mus musculus)
KALRN [cytosol] (Mus musculus)
MAPK family signaling cascades (Mus musculus)
MAPK6/MAPK4 signaling (Mus musculus)
MAPKAPK5 phosphorylates KALRN (Mus musculus)
KALRN:p-S189 MAPK6:p-T182 MAPKAPK5 [cytosol] (Mus musculus)
KALRN [cytosol] (Mus musculus)
p-S189 MAPK6:p-T182 MAPKAPK5 bind KALRN (Mus musculus)
KALRN [cytosol] (Mus musculus)
KALRN:p-S189 MAPK6:p-T182 MAPKAPK5 [cytosol] (Mus musculus)
KALRN [cytosol] (Mus musculus)
Signaling by GPCR (Mus musculus)
GPCR downstream signalling (Mus musculus)
G alpha (12/13) signalling events (Mus musculus)
GEFs activate RhoA,B,C (Mus musculus)
GEFs [cytosol] (Mus musculus)
KALRN [cytosol] (Mus musculus)
G alpha (q) signalling events (Mus musculus)
G alpha (q) binds to Trio family RhoGEFs (Mus musculus)
G-protein alpha (q/11):Trio family RhoGEFs [plasma membrane] (Mus musculus)
TRIO family RhoGEFs [cytosol] (Mus musculus)
KALRN [cytosol] (Mus musculus)
TRIO family RhoGEFs [cytosol] (Mus musculus)
KALRN [cytosol] (Mus musculus)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Mus musculus)
Signaling by Rho GTPases (Mus musculus)
RHO GTPase cycle (Mus musculus)
RAC1 GTPase cycle (Mus musculus)
RAC1 GEFs activate RAC1 (Mus musculus)
RAC1 GEFs [cytosol] (Mus musculus)
KALRN [cytosol] (Mus musculus)
RHOA GTPase cycle (Mus musculus)
RHOA GEFs activate RHOA (Mus musculus)
RHOA GEFs [cytosol] (Mus musculus)
KALRN [cytosol] (Mus musculus)
RHOG GTPase cycle (Mus musculus)
RHOG GEFs activate RHOG (Mus musculus)
RHOG GEFs [cytosol] (Mus musculus)
KALRN [cytosol] (Mus musculus)
External Reference Information
External Reference
UniProt:A2CG49
Reference Genes
BioGPS Gene:545156
ENSEMBL:ENSMUSG00000061751
ENSEMBL:ENSMUSG00000061751.17
KEGG Gene (Mus musculus):545156
Monarch:545156
NCBI Gene:545156
UCSC:A2CG49
Reference Transcript
RefSeq:XM_006522382.3
RefSeq:NM_001164268.1
Other Identifiers
10439138
136206_at
1429796_at
1436066_at
1457899_at
166134_at
17329946
4316888
4327038
4343345
4361730
4368114
4378635
4386577
4397090
4419629
4450356
4473919
4474420
4490926
4512128
4517733
4542847
4552735
4558039
4558877
4580924
4595723
4626068
4627501
4632240
4677865
4707647
4729982
4765941
4767405
4788750
4814674
4814931
4868487
4900581
4904385
4906382
4925142
4938094
4971836
4993347
5013342
5014102
5023035
5047342
5096303
5099767
5105483
5119583
5141148
5150121
5216370
5218761
5263029
5283369
5289124
5303442
5336562
5363289
5393458
5409467
5410900
5442661
545156
5468037
5513971
5518691
5534086
5543148
5545164
5551840
5551894
5554962
5563990
5589259
96556_at
99830_at
AA673405_rc_at
A_51_P215828
A_51_P400016
A_52_P600492
A_55_P2095814
A_55_P2095820
A_55_P2095844
A_55_P2160623
A_66_P108214
GE1400797
GE1519736
GE1553721
GE39309
GO:0000166
GO:0003824
GO:0004672
GO:0004674
GO:0005085
GO:0005515
GO:0005524
GO:0005634
GO:0005654
GO:0005737
GO:0005829
GO:0005856
GO:0006468
GO:0007399
GO:0007409
GO:0007411
GO:0007528
GO:0007595
GO:0007613
GO:0008344
GO:0014069
GO:0016301
GO:0016310
GO:0016740
GO:0019898
GO:0019899
GO:0022414
GO:0023052
GO:0030154
GO:0034330
GO:0035176
GO:0035556
GO:0036211
GO:0042711
GO:0043025
GO:0043226
GO:0046872
GO:0046959
GO:0048471
GO:0048856
GO:0050773
GO:0050877
GO:0060125
GO:0060137
GO:0061003
GO:0098696
GO:0098772
GO:0098793
GO:0098885
GO:0098978
GO:0098989
GO:0099645
GO:0106310
GO:0140096
GO:1905274
ILMN_1224913
ILMN_2529914
ILMN_2529915
ILMN_2740362
mMC022700
Participates
as a candidate of
RHOA GEFs [cytosol] (Mus musculus)
RAC1 GEFs [cytosol] (Mus musculus)
as a member of
RHOG GEFs [cytosol] (Mus musculus)
TRIO family RhoGEFs [cytosol] (Mus musculus)
GEFs [cytosol] (Mus musculus)
as an input of
p-S189 MAPK6:p-T182 MAPKAPK5 bind KALRN (Mus musculus)
EPHB2 binds KALRN (Mus musculus)
as a component of
KALRN:p-S189 MAPK6:p-T182 MAPKAPK5 [cytosol] (Mus musculus)
EFNBs:p-EPHBs:KALRN [plasma membrane] (Mus musculus)
Other forms of this molecule
phospho-p-KALRN [cytosol]
Inferred From
KALRN [cytosol]
(Homo sapiens)
Cross References
RefSeq
XP_006522445.1
,
NP_001157740.1
Ensembl
ENSMUSP00000110611
,
ENSMUSP00000110599
,
ENSMUST00000232157
,
ENSMUSG00000061751
,
ENSMUSP00000156147
,
ENSMUSP00000076088
,
ENSMUST00000089655
,
ENSMUSP00000110603
,
ENSMUSP00000110604
,
ENSMUST00000114960
,
ENSMUSP00000087084
,
ENSMUST00000114953
,
ENSMUST00000114949
,
ENSMUST00000114954
,
ENSMUST00000076810
PRO
A2CG49
MGI
2685385
PDB
7UR2
,
1WFW
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q4ACU6
1
Shank3 [cytosol]
(R-MMU-6794277)
0.527
2
UniProt:F6SEU4
1
Syngap1 [cytosol]
(R-MMU-5658217)
0.527
4
UniProt:Q62108 Dlg4
3
SAP-90 [plasma membrane]
(R-MMU-443606)
Dlg4 [endocytic vesicle membrane]
(R-MMU-416847)
Dlg4 [cytosol]
(R-MMU-6794267)
0.527
2
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