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RAPGEF4 [plasma membrane]
Stable Identifier
R-MMU-3008666
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
plasma membrane
Synonyms
Q9EQZ6
Locations in the PathwayBrowser
Expand all
Hemostasis (Mus musculus)
Platelet activation, signaling and aggregation (Mus musculus)
Platelet Aggregation (Plug Formation) (Mus musculus)
Integrin signaling (Mus musculus)
Activation of Rap1 by membrane-associated GEFs (Mus musculus)
Rap1 cAMP-GEFs [plasma membrane] (Mus musculus)
RAPGEF4 [plasma membrane] (Mus musculus)
Immune System (Mus musculus)
Adaptive Immune System (Mus musculus)
Rap1 signalling (Mus musculus)
Activation of EPACs by cAMP (Mus musculus)
Rap1 cAMP-GEFs [plasma membrane] (Mus musculus)
RAPGEF4 [plasma membrane] (Mus musculus)
Rap1 cAMP-GEFs:cAMP [cytosol] (Mus musculus)
Rap1 cAMP-GEFs [plasma membrane] (Mus musculus)
RAPGEF4 [plasma membrane] (Mus musculus)
Activation of Rap1 by membrane-associated GEFs (Mus musculus)
Rap1 cAMP-GEFs [plasma membrane] (Mus musculus)
RAPGEF4 [plasma membrane] (Mus musculus)
Metabolism (Mus musculus)
Integration of energy metabolism (Mus musculus)
Regulation of insulin secretion (Mus musculus)
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion (Mus musculus)
RAP1A exchanges GDP for GTP (Mus musculus)
RAPGEF4:cAMP Complex [plasma membrane] (Mus musculus)
RAPGEF4 [plasma membrane] (Mus musculus)
cAMP activates EPAC2 (Mus musculus)
RAPGEF4 [plasma membrane] (Mus musculus)
RAPGEF4:cAMP Complex [plasma membrane] (Mus musculus)
RAPGEF4 [plasma membrane] (Mus musculus)
KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel (Mus musculus)
RAPGEF4:cAMP Complex [plasma membrane] (Mus musculus)
RAPGEF4 [plasma membrane] (Mus musculus)
Signal Transduction (Mus musculus)
Integrin signaling (Mus musculus)
Activation of Rap1 by membrane-associated GEFs (Mus musculus)
Rap1 cAMP-GEFs [plasma membrane] (Mus musculus)
RAPGEF4 [plasma membrane] (Mus musculus)
External Reference Information
External Reference
UniProt:Q9EQZ6
Reference Genes
BioGPS Gene:56508
ENSEMBL:ENSMUSG00000049044
ENSEMBL:ENSMUSG00000049044.17
KEGG Gene (Mus musculus):56508
Monarch:56508
NCBI Gene:56508
UCSC:Q9EQZ6
Reference Transcript
RefSeq:NM_001204165.1
RefSeq:NM_001204166.1
RefSeq:NM_019688.2
Other Identifiers
10472860
106462_g_at
1421622_a_at
1425518_at
163318_at
17371873
4359383
4378254
4417491
4535976
4544312
4546567
4615587
4629472
4677994
4713633
4722627
4731643
4781174
4807498
4947201
4991040
4999738
5041330
5082196
5133445
5176390
5226825
5231574
5233829
5348190
5371188
5379703
5381241
5423145
5432451
5503335
5519200
5526896
5591080
56508
92659_at
A_51_P285916
A_52_P292498
A_55_P2484679
GE40092
GO:0000166
GO:0001750
GO:0001917
GO:0005085
GO:0005515
GO:0005737
GO:0005829
GO:0005886
GO:0005903
GO:0005929
GO:0006887
GO:0007188
GO:0007189
GO:0007264
GO:0007265
GO:0014069
GO:0014911
GO:0016020
GO:0016192
GO:0016323
GO:0016324
GO:0017156
GO:0017157
GO:0023052
GO:0030073
GO:0030154
GO:0030424
GO:0030425
GO:0030426
GO:0030552
GO:0030674
GO:0031267
GO:0032024
GO:0032991
GO:0034330
GO:0035556
GO:0043025
GO:0043197
GO:0043226
GO:0044316
GO:0044877
GO:0046879
GO:0048856
GO:0048870
GO:0050714
GO:0050773
GO:0050805
GO:0050877
GO:0060076
GO:0060090
GO:0098686
GO:0098693
GO:0098696
GO:0098772
GO:0098978
GO:0099175
GO:1904457
ILMN_2634226
ILMN_2945940
mMC023831
Participates
as a member of
Rap1 cAMP-GEFs [plasma membrane] (Mus musculus)
as an input of
cAMP activates EPAC2 (Mus musculus)
as a component of
RAPGEF4:cAMP Complex [plasma membrane] (Mus musculus)
Inferred From
RAPGEF4 [plasma membrane]
(Homo sapiens)
Cross References
RefSeq
NP_001191094.1
,
NP_001191095.1
,
NP_062662.1
Ensembl
ENSMUST00000090826
,
ENSMUST00000102698
,
ENSMUSG00000049044
,
ENSMUSP00000099759
,
ENSMUSP00000088336
PRO
Q9EQZ6
MGI
1917723
PDB
3CF6
,
4MGI
,
4MH0
,
4MGK
,
4MGY
,
4F7Z
,
4MGZ
,
1O7F
,
2BYV
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P01112 HRAS
20
HRAS Q61R [plasma membrane]
(R-HSA-6802458)
HRAS Q61L [plasma membrane]
(R-HSA-6802452)
HRAS Q61K [plasma membrane]
(R-HSA-6802442)
HRAS G13R [plasma membrane]
(R-HSA-6802368)
HRAS G12V [plasma membrane]
(R-HSA-6802350)
HRAS G12S [plasma membrane]
(R-HSA-6802343)
HRAS T58I [plasma membrane]
(R-HSA-9656014)
HRAS G13C [plasma membrane]
(R-HSA-9656008)
HRAS K117R [plasma membrane]
(R-HSA-9656010)
HRAS G13V [plasma membrane]
(R-HSA-9656579)
HRAS G13D [plasma membrane]
(R-HSA-9656572)
HRAS G13S [plasma membrane]
(R-HSA-9656574)
HRAS K117N [plasma membrane]
(R-HSA-9656603)
HRAS G12D [plasma membrane]
(R-HSA-9656564)
HRAS G12C [plasma membrane]
(R-HSA-9656561)
HRAS [plasma membrane]
(R-HSA-62717)
S-Farn-Me HRAS [plasma membrane]
(R-HSA-9665052)
S-Farn-Me PalmS HRAS [Golgi membrane]
(R-HSA-9647896)
S-Farn-Me HRAS [endoplasmic reticulum membrane]
(R-HSA-9647796)
S-Farn-HRAS [endoplasmic reticulum membrane]
(R-HSA-9647788)
0.556
3
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