Reactome | SMYD2 [nucleoplasm]

SMYD2 [nucleoplasm]

Stable Identifier

R-MMU-3222233

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

nucleoplasm

Synonyms

Q8R5A0

Locations in the PathwayBrowser

Expand all

Gene expression (Transcription) (Mus musculus)

- RNA Polymerase II Transcription (Mus musculus)
  - Generic Transcription Pathway (Mus musculus)
    - Transcriptional Regulation by TP53 (Mus musculus)
      - Regulation of TP53 Activity (Mus musculus)
        
        Regulation of TP53 Activity through Methylation (Mus musculus)
        
        SMYD2 methylates TP53 (Mus musculus)
        
        SMYD2 [nucleoplasm] (Mus musculus)

External Reference Information

External Reference

UniProt:Q8R5A0

Reference Genes

BioGPS Gene:226830

ENSEMBL:ENSMUSG00000026603

KEGG:mmu:226830

Monarch:226830

NCBI Gene:226830

UCSC:Q8R5A0

Reference Transcript

RefSeq:NM_026796.1

Other Identifiers

10361007

1424760_a_at

160794_at

17230945

226830

4409661

4427512

4455178

4462124

4619517

4663988

4667851

4724769

4744399

4752835

4754447

4772217

4830460

4842424

4943202

5017121

5039920

5143671

5176393

5268575

5278910

5291540

5393188

5458671

5491964

5579585

A_66_P140441

GE42337

GO:0000122

GO:0000993

GO:0002039

GO:0003824

GO:0005515

GO:0005634

GO:0005737

GO:0005829

GO:0006325

GO:0006338

GO:0006355

GO:0007507

GO:0008168

GO:0008285

GO:0016279

GO:0016740

GO:0018026

GO:0018027

GO:0032259

GO:0042054

GO:0043226

GO:0043516

GO:0046872

GO:0046975

GO:0048856

GO:0140096

GO:0140999

ILMN_2674001

ILMN_2957161

mMC007978

w76826_at

Participates

as a member of

WHSC1, NSD1, SMYD2, ASH1L [nucleoplasm] (Mus musculus)

Inferred From

SMYD2 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_081072.1

ENSEMBL

ENSMUST00000027897, ENSMUSP00000027897

PRO

Q8R5A0

MGI

1915889

PDB

3QWV, 3QWW

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P04637 TP53	20	Unfolded TP53 [cytosol] (R-HSA-6813797) TP53 [cytosol] (R-HSA-8869337) PolyUb-TP53 [nucleoplasm] (R-HSA-6782509) polySUMO2,3-K386-TP53 [nucleoplasm] (R-HSA-2997661) TP53 F341C [nucleoplasm] (R-HSA-9726318) TP53 G334V [nucleoplasm] (R-HSA-9726126) TP53 L330H [nucleoplasm] (R-HSA-9726124) TP53 A347T [nucleoplasm] (R-HSA-9726339) TP53 R337C [nucleoplasm] (R-HSA-9726118) TP53 L344P [nucleoplasm] (R-HSA-9726075) TP53 L344R [nucleoplasm] (R-HSA-9726073) TP53 R337H [nucleoplasm] (R-HSA-9726169) TP53 R337P [nucleoplasm] (R-HSA-9726168) TP53 L330P [nucleoplasm] (R-HSA-9726136) TP53 L348S [nucleoplasm] (R-HSA-9726366) TP53 R337L [nucleoplasm] (R-HSA-9726163) TP53 K351E [nucleoplasm] (R-HSA-9726258) TP53 F338I [nucleoplasm] (R-HSA-9726358) TP53 R342P [nucleoplasm] (R-HSA-9726101) TP53 L330R [nucleoplasm] (R-HSA-9726133)	0.544	3