Ptpmt1 dephosphorylates PGP to PG

Stable Identifier
R-MMU-3446785
Type
Reaction [transition]
Species
Mus musculus
Compartment
General
SVG |   | PPTX  | SBGN
Ptpmt1 dephosphorylates PGP to PG

At the inner mitochondrial (IM) membrane, Ptpmt1 (phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1) catalyzes the dephosphorylation of phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) (Zhang et al. 2011).

Literature References
PubMed ID Title Journal Year
21641550 Mitochondrial phosphatase PTPMT1 is essential for cardiolipin biosynthesis

Zhang, J, Guan, Z, Murphy, AN, Wiley, SE, Perkins, GA, Worby, CA, Engel, JL, Heacock, P, Nguyen, OK, Wang, JH, Raetz, CR, Dowhan, W, Dixon, JE

Cell Metab. 2011
Participants
Catalyst Activity
Catalyst Activity
Title
phosphatidylglycerophosphatase activity of Ptpmt1 [mitochondrial inner membrane]
Physical Entity
Activity
Orthologous Events
Authored
Reviewed
Created