Reactome | Ccp110 [cytosol]

Ccp110 [cytosol]

Stable Identifier

R-MMU-380261

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

cytosol

Synonyms

CCP110, Q7TSH4

Locations in the PathwayBrowser

Expand all

Metabolism of proteins (Mus musculus)

- Post-translational protein modification (Mus musculus)
  - Deubiquitination (Mus musculus)
    - Ub-specific processing proteases (Mus musculus)
      - USP33 deubiquitinates CCP110,ARRB (Mus musculus)
        
        USP33:CCP110,ARRB1,ARRB2 [cytosol] (Mus musculus)
        
        CCP110,ARRB2,(ARRB1) [cytosol] (Mus musculus)
        
        Ccp110 [cytosol] (Mus musculus)

Organelle biogenesis and maintenance (Mus musculus)

- Cilium Assembly (Mus musculus)
  - Anchoring of the basal body to the plasma membrane (Mus musculus)
    - C2CD3 and OFD1 recruit 5 distal appendage proteins to the centriole (Mus musculus)
      - Centrosome:C2CD3:distal appendage proteins [cytosol] (Mus musculus)
        
        mother centriole:C2CD3 [cytosol] (Mus musculus)
        
        mother centriole [cytosol] (Mus musculus)
        
        Ccp110 [cytosol] (Mus musculus)
      - mother centriole:C2CD3 [cytosol] (Mus musculus)
        
        mother centriole [cytosol] (Mus musculus)
        
        Ccp110 [cytosol] (Mus musculus)
    - C2CD3 binds the mother centriole (Mus musculus)
      - mother centriole [cytosol] (Mus musculus)
        
        Ccp110 [cytosol] (Mus musculus)
      - mother centriole:C2CD3 [cytosol] (Mus musculus)
        
        mother centriole [cytosol] (Mus musculus)
        
        Ccp110 [cytosol] (Mus musculus)
    - CP110 and CEP97 dissociate from the centriole (Mus musculus)
      - Ccp110 [cytosol] (Mus musculus)
      - centrosome:C2CD2:distal appendage proteins:TTBK2:MARK4 [cytosol] (Mus musculus)
        
        Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Mus musculus)
        
        Centrosome:C2CD3:distal appendage proteins [cytosol] (Mus musculus)
        
        mother centriole:C2CD3 [cytosol] (Mus musculus)
        
        mother centriole [cytosol] (Mus musculus)
        
        Ccp110 [cytosol] (Mus musculus)
    - MARK4 binds ODF2 in the centriole (Mus musculus)
      - Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Mus musculus)
        
        Centrosome:C2CD3:distal appendage proteins [cytosol] (Mus musculus)
        
        mother centriole:C2CD3 [cytosol] (Mus musculus)
        
        mother centriole [cytosol] (Mus musculus)
        
        Ccp110 [cytosol] (Mus musculus)
      - centrosome:C2CD2:distal appendage proteins:TTBK2:MARK4 [cytosol] (Mus musculus)
        
        Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Mus musculus)
        
        Centrosome:C2CD3:distal appendage proteins [cytosol] (Mus musculus)
        
        mother centriole:C2CD3 [cytosol] (Mus musculus)
        
        mother centriole [cytosol] (Mus musculus)
        
        Ccp110 [cytosol] (Mus musculus)
    - The distal appendage proteins recruit TTBK2 (Mus musculus)
      - Centrosome:C2CD3:distal appendage proteins [cytosol] (Mus musculus)
        
        mother centriole:C2CD3 [cytosol] (Mus musculus)
        
        mother centriole [cytosol] (Mus musculus)
        
        Ccp110 [cytosol] (Mus musculus)
      - Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Mus musculus)
        
        Centrosome:C2CD3:distal appendage proteins [cytosol] (Mus musculus)
        
        mother centriole:C2CD3 [cytosol] (Mus musculus)
        
        mother centriole [cytosol] (Mus musculus)
        
        Ccp110 [cytosol] (Mus musculus)

External Reference Information

External Reference

UniProt:Q7TSH4

Gene Names

Ccp110

Reference Genes

BioGPS Gene:101565 Ccp110

ENSEMBL:ENSMUSG00000033904

ENSEMBL:ENSMUSG00000033904.17 Ccp110

KEGG Gene (Mus musculus):101565 Ccp110

Monarch:101565 Ccp110

NCBI Gene:101565 Ccp110

UCSC:Q7TSH4 Ccp110

Reference Transcript

RefSeq:NM_182995.1 Ccp110

Other Identifiers

101565

10556640

114168_at

138208_at

1455218_at

17482160

4369630

4423873

4438813

4817240

4869337

4890807

4923952

4932126

5009169

5020373

5075200

5096874

5122008

5139466

5194781

5242649

5309295

5381683

5401970

5417331

5476574

5498562

5597218

5606893

A_52_P344160

A_52_P479038

A_55_P2047559

GE1530738

GO:0000910

GO:0005515

GO:0005737

GO:0005813

GO:0005814

GO:0005815

GO:0005856

GO:0005929

GO:0007010

GO:0007099

GO:0030030

GO:0032053

GO:0032465

GO:0032991

GO:0042995

GO:0043226

GO:0044782

GO:0045724

GO:0051298

GO:1902018

GO:1903723

ILMN_1224182

ILMN_1228426

ILMN_3006575

mMC021711

Participates

as a candidate of

RHOV effectors [cytosol] (Mus musculus)

as an output of

CP110 and CEP97 dissociate from the centriole (Mus musculus)

as a component of

as a member of

CCP110,ARRB2,(ARRB1) [cytosol] (Mus musculus)

Other forms of this molecule

Ccp110 [cytosol]

Inferred From

CCP110 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_892040.1

Ensembl

ENSMUSP00000038881, ENSMUST00000106557, ENSMUSG00000033904, ENSMUSP00000102167, ENSMUST00000038650

PRO

Q7TSH4

MGI

2141942

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q6A078	3	Cep290 [extracellular region] (R-MMU-6806291) Cep290 [specific granule lumen] (R-MMU-6799524) Cep290 [cytosol] (R-MMU-380275)	0.623	3

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