Sumoylation of Ncor2 with Sumo1

Stable Identifier
R-MMU-3927808
Type
Reaction [transition]
Species
Mus musculus
Compartment
nucleoplasm
General
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Sumoylation of Ncor2 with Sumo1

Ncor2 (Smrt) is sumoylated at lysine-668 with Sumo1 (Jiang et al. 2010). Sumoylation reduces repression of transcription by Ncor2.

Literature References
PubMed ID Title Journal Year
20555024 Aberrant expression and modification of silencing mediator of retinoic acid and thyroid hormone receptors involved in the pathogenesis of tumoral cortisol resistance

Jiang, J, Li, N, Wang, X, Lu, Y, Bi, Y, Wang, W, Li, X, Ning, G

Endocrinology 2010
Participants
Input
Output
Catalyst Activity

SUMO transferase activity of Sumo1:C93-Ube2i [nucleoplasm]

Physical Entity
Sumo1:C93-Ube2i [nucleoplasm] (Mus musculus)
Activity
SUMO transferase activity (GO:0019789)
Orthologous Events
SUMOylation of NCOR2 with SUMO1 (Homo sapiens)
Authored
May, B  (2013-07-17)
Reviewed
Niskanen, E  (2018-05-09)
Niskanen, E  (2018-08-08)
Created
May, B  (2013-07-21)
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