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ROCK2 [cytosol]
Stable Identifier
R-MMU-419058
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
cytosol
Synonyms
P70336
Locations in the PathwayBrowser
Expand all
Developmental Biology (Mus musculus)
Nervous system development (Mus musculus)
Axon guidance (Mus musculus)
EPH-Ephrin signaling (Mus musculus)
EPHB-mediated forward signaling (Mus musculus)
RHOA:GTP binds ROCK, activating it (Mus musculus)
RHOA:GTP:ROCK1,ROCK2 [plasma membrane] (Mus musculus)
ROCK1,ROCK2 [cytosol] (Mus musculus)
ROCK2 [cytosol] (Mus musculus)
ROCK1,ROCK2 [cytosol] (Mus musculus)
ROCK2 [cytosol] (Mus musculus)
Semaphorin interactions (Mus musculus)
Sema4D in semaphorin signaling (Mus musculus)
Sema4D induced cell migration and growth-cone collapse (Mus musculus)
ROCK activation by RHO (Mus musculus)
Activated ROCK:RhoA/B/C:GTP [plasma membrane] (Mus musculus)
ROCK1,ROCK2 [cytosol] (Mus musculus)
ROCK2 [cytosol] (Mus musculus)
ROCK1,ROCK2 [cytosol] (Mus musculus)
ROCK2 [cytosol] (Mus musculus)
ROCK1,ROCK2:ROCKi [cytosol] (Mus musculus)
ROCK1,ROCK2 [cytosol] (Mus musculus)
ROCK2 [cytosol] (Mus musculus)
ROCK1,2 bind ROCKi (Mus musculus)
ROCK1,ROCK2 [cytosol] (Mus musculus)
ROCK2 [cytosol] (Mus musculus)
ROCK1,ROCK2:ROCKi [cytosol] (Mus musculus)
ROCK1,ROCK2 [cytosol] (Mus musculus)
ROCK2 [cytosol] (Mus musculus)
Signal Transduction (Mus musculus)
Signaling by GPCR (Mus musculus)
GPCR downstream signalling (Mus musculus)
G alpha (12/13) signalling events (Mus musculus)
ROCK activation by RHO (Mus musculus)
Activated ROCK:RhoA/B/C:GTP [plasma membrane] (Mus musculus)
ROCK1,ROCK2 [cytosol] (Mus musculus)
ROCK2 [cytosol] (Mus musculus)
ROCK1,ROCK2 [cytosol] (Mus musculus)
ROCK2 [cytosol] (Mus musculus)
ROCK1,ROCK2:ROCKi [cytosol] (Mus musculus)
ROCK1,ROCK2 [cytosol] (Mus musculus)
ROCK2 [cytosol] (Mus musculus)
ROCK1,2 bind ROCKi (Mus musculus)
ROCK1,ROCK2 [cytosol] (Mus musculus)
ROCK2 [cytosol] (Mus musculus)
ROCK1,ROCK2:ROCKi [cytosol] (Mus musculus)
ROCK1,ROCK2 [cytosol] (Mus musculus)
ROCK2 [cytosol] (Mus musculus)
Signaling by Receptor Tyrosine Kinases (Mus musculus)
Signaling by VEGF (Mus musculus)
VEGFA-VEGFR2 Pathway (Mus musculus)
Active ROCK1,ROCK2 phosphorylates p-5Y-PTK2 on S732 (Mus musculus)
RHOA:GTP:Mg2+:Activated ROCK1,ROCK2 [cytosol] (Mus musculus)
ROCK1,ROCK2 [cytosol] (Mus musculus)
ROCK2 [cytosol] (Mus musculus)
RHOA:GTP:Mg2+ binds ROCK1,ROCK2 (Mus musculus)
RHOA:GTP:ROCK1,ROCK2 [plasma membrane] (Mus musculus)
ROCK1,ROCK2 [cytosol] (Mus musculus)
ROCK2 [cytosol] (Mus musculus)
ROCK1,ROCK2 [cytosol] (Mus musculus)
ROCK2 [cytosol] (Mus musculus)
ROCK1,ROCK2 are activated (Mus musculus)
RHOA:GTP:Mg2+:Activated ROCK1,ROCK2 [cytosol] (Mus musculus)
ROCK1,ROCK2 [cytosol] (Mus musculus)
ROCK2 [cytosol] (Mus musculus)
RHOA:GTP:ROCK1,ROCK2 [plasma membrane] (Mus musculus)
ROCK1,ROCK2 [cytosol] (Mus musculus)
ROCK2 [cytosol] (Mus musculus)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Mus musculus)
Signaling by Rho GTPases (Mus musculus)
RHO GTPase Effectors (Mus musculus)
RHO GTPases Activate ROCKs (Mus musculus)
ROCK activation by RHO (Mus musculus)
Activated ROCK:RhoA/B/C:GTP [plasma membrane] (Mus musculus)
ROCK1,ROCK2 [cytosol] (Mus musculus)
ROCK2 [cytosol] (Mus musculus)
ROCK1,ROCK2 [cytosol] (Mus musculus)
ROCK2 [cytosol] (Mus musculus)
ROCK1,ROCK2:ROCKi [cytosol] (Mus musculus)
ROCK1,ROCK2 [cytosol] (Mus musculus)
ROCK2 [cytosol] (Mus musculus)
ROCK1,2 bind ROCKi (Mus musculus)
ROCK1,ROCK2 [cytosol] (Mus musculus)
ROCK2 [cytosol] (Mus musculus)
ROCK1,ROCK2:ROCKi [cytosol] (Mus musculus)
ROCK1,ROCK2 [cytosol] (Mus musculus)
ROCK2 [cytosol] (Mus musculus)
RHO GTPase cycle (Mus musculus)
RHOA GTPase cycle (Mus musculus)
RHOA binds effectors at the plasma membrane (Mus musculus)
RHOA plasma membrane effectors [cytosol] (Mus musculus)
ROCK2 [cytosol] (Mus musculus)
RHOA:GTP:cytosolic RHOA effectors [plasma membrane] (Mus musculus)
RHOA plasma membrane effectors [cytosol] (Mus musculus)
ROCK2 [cytosol] (Mus musculus)
RHOB GTPase cycle (Mus musculus)
RHOB binds effectors at the plasma membrane (Mus musculus)
RHOB effectors (plasma membrane) [cytosol] (Mus musculus)
ROCK2 [cytosol] (Mus musculus)
RHOB:GTP:cytosolic RHOB effectors [plasma membrane] (Mus musculus)
RHOB effectors (plasma membrane) [cytosol] (Mus musculus)
ROCK2 [cytosol] (Mus musculus)
RHOBTB GTPase Cycle (Mus musculus)
RHOBTB1 GTPase cycle (Mus musculus)
RHOBTB1 binds interacting proteins at the endosome membrane (Mus musculus)
RHOBTB1 interacting proteins [cytosol] (Mus musculus)
ROCK2 [cytosol] (Mus musculus)
RHOBTB1:GTP:RHOBTB1 interacting proteins [endosome membrane] (Mus musculus)
RHOBTB1 interacting proteins [cytosol] (Mus musculus)
ROCK2 [cytosol] (Mus musculus)
RHOC GTPase cycle (Mus musculus)
RHOC binds effectors at the plasma membrane (Mus musculus)
RHOC effectors [cytosol] (Mus musculus)
ROCK2 [cytosol] (Mus musculus)
RHOC:GTP:RHOC effectors [plasma membrane] (Mus musculus)
RHOC effectors [cytosol] (Mus musculus)
ROCK2 [cytosol] (Mus musculus)
RHOH GTPase cycle (Mus musculus)
RHOH binds effectors at the plasma membrane (Mus musculus)
RHOH effectors [cytosol] (Mus musculus)
ROCK2 [cytosol] (Mus musculus)
RHOH:GTP:RHOH effectors [plasma membrane] (Mus musculus)
RHOH effectors [cytosol] (Mus musculus)
ROCK2 [cytosol] (Mus musculus)
External Reference Information
External Reference
UniProt:P70336
Reference Genes
BioGPS Gene:19878
ENSEMBL:ENSMUSG00000020580
KEGG:mmu:19878
Monarch:19878
NCBI Gene:19878
UCSC:P70336
Reference Transcript
RefSeq:NM_009072.2
Participates
as a member of
RHOA plasma membrane effectors [cytosol] (Mus musculus)
RHOC effectors [cytosol] (Mus musculus)
RHOBTB1 interacting proteins [cytosol] (Mus musculus)
RHOB effectors (plasma membrane) [cytosol] (Mus musculus)
ROCK1,ROCK2 [cytosol] (Mus musculus)
as a candidate of
RHOH effectors [cytosol] (Mus musculus)
Inferred From
Activated ROCK2 [cytosol]
(Homo sapiens)
ROCK2 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_033098.2
PRO
P70336
MGI
107926
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