Reactome | Lpar3 [plasma membrane]

Lpar3 [plasma membrane]

Stable Identifier

R-MMU-419379

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

plasma membrane

Synonyms

LPAR3, Q9EQ31

Locations in the PathwayBrowser

Expand all

Signal Transduction (Mus musculus)

- Signaling by GPCR (Mus musculus)
  - GPCR downstream signalling (Mus musculus)
    - G alpha (i) signalling events (Mus musculus)
      - Liganded Gi-activating GPCR acts as a GEF for Gi (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        LPAR1,2,3,5:LPA [plasma membrane] (Mus musculus)
        
        LPAR1,2,3,5 [plasma membrane] (Mus musculus)
        
        Lpar3 [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        LPAR1,2,3,5:LPA [plasma membrane] (Mus musculus)
        
        LPAR1,2,3,5 [plasma membrane] (Mus musculus)
        
        Lpar3 [plasma membrane] (Mus musculus)
      - Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        LPAR1,2,3,5:LPA [plasma membrane] (Mus musculus)
        
        LPAR1,2,3,5 [plasma membrane] (Mus musculus)
        
        Lpar3 [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        LPAR1,2,3,5:LPA [plasma membrane] (Mus musculus)
        
        LPAR1,2,3,5 [plasma membrane] (Mus musculus)
        
        Lpar3 [plasma membrane] (Mus musculus)
      - The Ligand:GPCR:Gi complex dissociates (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        LPAR1,2,3,5:LPA [plasma membrane] (Mus musculus)
        
        LPAR1,2,3,5 [plasma membrane] (Mus musculus)
        
        Lpar3 [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        LPAR1,2,3,5:LPA [plasma membrane] (Mus musculus)
        
        LPAR1,2,3,5 [plasma membrane] (Mus musculus)
        
        Lpar3 [plasma membrane] (Mus musculus)
    - G alpha (q) signalling events (Mus musculus)
      - Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
        
        LPAR1,2,3,5:LPA [plasma membrane] (Mus musculus)
        
        LPAR1,2,3,5 [plasma membrane] (Mus musculus)
        
        Lpar3 [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
        
        LPAR1,2,3,5:LPA [plasma membrane] (Mus musculus)
        
        LPAR1,2,3,5 [plasma membrane] (Mus musculus)
        
        Lpar3 [plasma membrane] (Mus musculus)
      - Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
        
        LPAR1,2,3,5:LPA [plasma membrane] (Mus musculus)
        
        LPAR1,2,3,5 [plasma membrane] (Mus musculus)
        
        Lpar3 [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
        
        LPAR1,2,3,5:LPA [plasma membrane] (Mus musculus)
        
        LPAR1,2,3,5 [plasma membrane] (Mus musculus)
        
        Lpar3 [plasma membrane] (Mus musculus)
      - The Ligand:GPCR:Gq complex dissociates (Mus musculus)
        
        GPCRs that activate Gq/11 [plasma membrane] (Mus musculus)
        
        LPAR1,2,3,5 [plasma membrane] (Mus musculus)
        
        Lpar3 [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
        
        LPAR1,2,3,5:LPA [plasma membrane] (Mus musculus)
        
        LPAR1,2,3,5 [plasma membrane] (Mus musculus)
        
        Lpar3 [plasma membrane] (Mus musculus)
  - GPCR ligand binding (Mus musculus)
    - Class A/1 (Rhodopsin-like receptors) (Mus musculus)
      - Lysosphingolipid and LPA receptors (Mus musculus)
        
        LPA-binding receptors bind LPA (Mus musculus)
        
        LPAR1,2,3,5 [plasma membrane] (Mus musculus)
        
        Lpar3 [plasma membrane] (Mus musculus)
        
        LPAR1,2,3,5:LPA [plasma membrane] (Mus musculus)
        
        LPAR1,2,3,5 [plasma membrane] (Mus musculus)
        
        Lpar3 [plasma membrane] (Mus musculus)

External Reference Information

External Reference

UniProt:Q9EQ31

Gene Names

Lpar3

Reference Genes

BioGPS Gene:65086 Lpar3

ENSEMBL:ENSMUSG00000036832

ENSEMBL:ENSMUSG00000036832.6 Lpar3

KEGG Gene (Mus musculus):65086 Lpar3

Monarch:65086 Lpar3

NCBI Gene:65086 Lpar3

UCSC:Q9EQ31 Lpar3

Reference Transcript

RefSeq:NM_022983.4 Lpar3

Other Identifiers

10496789

1418723_at

17403509

4401312

4430000

4596403

4712377

4968040

5169588

5549199

65086

GE38244

GO:0001965

GO:0004930

GO:0005543

GO:0005737

GO:0005886

GO:0007165

GO:0007186

GO:0007189

GO:0008289

GO:0010467

GO:0016020

GO:0019222

GO:0023052

GO:0030154

GO:0030424

GO:0032060

GO:0043410

GO:0048668

GO:0048672

GO:0048856

GO:0051928

GO:0060089

GO:0070915

ILMN_2596435

ILMN_3009440

mMC003785

Participates

as a member of

LPAR1,2,3,5 [plasma membrane] (Mus musculus)

Inferred From

LPAR3 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_075359.1

Ensembl

ENSMUST00000039164, ENSMUSP00000037712, ENSMUSG00000036832

PRO

Q9EQ31

MGI

1929469

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