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Met [plasma membrane]
Stable Identifier
R-MMU-419603
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
plasma membrane
Synonyms
MET, P16056
Locations in the PathwayBrowser
Expand all
Developmental Biology (Mus musculus)
Nervous system development (Mus musculus)
Axon guidance (Mus musculus)
Semaphorin interactions (Mus musculus)
Sema4D in semaphorin signaling (Mus musculus)
Sema4D mediated inhibition of cell attachment and migration (Mus musculus)
Active Rac1 interacts with Plexin-B1:Sema4D (Mus musculus)
SEMA4D:MET:p-Y-PLXNB1 [plasma membrane] (Mus musculus)
MET:p-Y-PLXNB1 [plasma membrane] (Mus musculus)
Met [plasma membrane] (Mus musculus)
Sema4D:pPlexin-B1:Met:RAC1-GTP [plasma membrane] (Mus musculus)
SEMA4D:MET:p-Y-PLXNB1 [plasma membrane] (Mus musculus)
MET:p-Y-PLXNB1 [plasma membrane] (Mus musculus)
Met [plasma membrane] (Mus musculus)
Inactivation of R-Ras by Sema4D-Plexin-B1 GAP activity (Mus musculus)
SEMA4D:MET:p-Y-PLXNB1:RND1:GTP [plasma membrane] (Mus musculus)
SEMA4D:MET:p-Y-PLXNB1 [plasma membrane] (Mus musculus)
MET:p-Y-PLXNB1 [plasma membrane] (Mus musculus)
Met [plasma membrane] (Mus musculus)
Inactivation of Rho-GTP by p190RhoGAP (Mus musculus)
SEMA4D:MET:p-Y-PLXNB1:RND1:GTP:ARHGAP35 [plasma membrane] (Mus musculus)
SEMA4D:MET:p-Y-PLXNB1:RND1:GTP [plasma membrane] (Mus musculus)
SEMA4D:MET:p-Y-PLXNB1 [plasma membrane] (Mus musculus)
MET:p-Y-PLXNB1 [plasma membrane] (Mus musculus)
Met [plasma membrane] (Mus musculus)
Rnd1 interacts with Plexin-B1:Sema4D (Mus musculus)
SEMA4D:MET:p-Y-PLXNB1 [plasma membrane] (Mus musculus)
MET:p-Y-PLXNB1 [plasma membrane] (Mus musculus)
Met [plasma membrane] (Mus musculus)
SEMA4D:MET:p-Y-PLXNB1:RND1:GTP [plasma membrane] (Mus musculus)
SEMA4D:MET:p-Y-PLXNB1 [plasma membrane] (Mus musculus)
MET:p-Y-PLXNB1 [plasma membrane] (Mus musculus)
Met [plasma membrane] (Mus musculus)
SEMA4D interacts with Plexin-B1:Met (Mus musculus)
Met [plasma membrane] (Mus musculus)
Plexin-B1:Met [plasma membrane] (Mus musculus)
Met [plasma membrane] (Mus musculus)
SEMA4D:MET:p-Y-PLXNB1 [plasma membrane] (Mus musculus)
MET:p-Y-PLXNB1 [plasma membrane] (Mus musculus)
Met [plasma membrane] (Mus musculus)
p190RhoGAP binds Plexin-B1 (Mus musculus)
SEMA4D:MET:p-Y-PLXNB1:RND1:GTP [plasma membrane] (Mus musculus)
SEMA4D:MET:p-Y-PLXNB1 [plasma membrane] (Mus musculus)
MET:p-Y-PLXNB1 [plasma membrane] (Mus musculus)
Met [plasma membrane] (Mus musculus)
SEMA4D:MET:p-Y-PLXNB1:RND1:GTP:ARHGAP35 [plasma membrane] (Mus musculus)
SEMA4D:MET:p-Y-PLXNB1:RND1:GTP [plasma membrane] (Mus musculus)
SEMA4D:MET:p-Y-PLXNB1 [plasma membrane] (Mus musculus)
MET:p-Y-PLXNB1 [plasma membrane] (Mus musculus)
Met [plasma membrane] (Mus musculus)
Signal Transduction (Mus musculus)
Signaling by Receptor Tyrosine Kinases (Mus musculus)
Signaling by MET (Mus musculus)
MET Receptor Activation (Mus musculus)
HGF dimer binds MET (Mus musculus)
HGF dimer:MET [plasma membrane] (Mus musculus)
Met [plasma membrane] (Mus musculus)
Met [plasma membrane] (Mus musculus)
MET dimers autophosphorylate (Mus musculus)
HGF:MET dimer [plasma membrane] (Mus musculus)
HGF dimer:MET [plasma membrane] (Mus musculus)
Met [plasma membrane] (Mus musculus)
MET receptor dimerizes (Mus musculus)
HGF dimer:MET [plasma membrane] (Mus musculus)
Met [plasma membrane] (Mus musculus)
HGF:MET dimer [plasma membrane] (Mus musculus)
HGF dimer:MET [plasma membrane] (Mus musculus)
Met [plasma membrane] (Mus musculus)
Negative regulation of MET activity (Mus musculus)
EPS15 and HGS bind ubiquitinated MET (Mus musculus)
HGF:MonoUb-K,p-4Y-MET dimer:GRB2:p-Y-CBL,(HGF:MonoUb-K,p-Y1003,4Y-METdimer:p-Y-CBL):CIN85:endophillin,(MET:Ub-LRIG1) [plasma membrane] (Mus musculus)
MET:Ub-LRIG1 [plasma membrane] (Mus musculus)
Met [plasma membrane] (Mus musculus)
HGF:MonoUb-K,p-4Y-MET dimer:GRB2:p-Y-CBL,(HGF:MonoUb-K,p-Y1003,4Y-METdimer:p-Y-CBL):CIN85:endophillin:EPS15:HGS:STAM,(MET:Ub-LRIG1:EPS15:HGS:STAM) [plasma membrane] (Mus musculus)
HGF:MonoUb-K,p-4Y-MET dimer:GRB2:p-Y-CBL,(HGF:MonoUb-K,p-Y1003,4Y-METdimer:p-Y-CBL):CIN85:endophillin,(MET:Ub-LRIG1) [plasma membrane] (Mus musculus)
MET:Ub-LRIG1 [plasma membrane] (Mus musculus)
Met [plasma membrane] (Mus musculus)
MET binds LRIG1 (Mus musculus)
MET:LRIG1 [plasma membrane] (Mus musculus)
Met [plasma membrane] (Mus musculus)
Met [plasma membrane] (Mus musculus)
USP8 deubiquitinates LRIG1 (Mus musculus)
MET:LRIG1 [plasma membrane] (Mus musculus)
Met [plasma membrane] (Mus musculus)
MET:Ub-LRIG1 [plasma membrane] (Mus musculus)
Met [plasma membrane] (Mus musculus)
External Reference Information
External Reference
UniProt:P16056
Gene Names
Met
Reference Genes
ENSEMBL:ENSMUSG00000009376
Participant Of
input
HGF dimer binds MET
MET binds LRIG1
hasComponent
HGF dimer:MET [plasma membrane]
MET:LRIG1 [plasma membrane]
MET:p-Y-PLXNB1 [plasma membrane]
MET:Ub-LRIG1 [plasma membrane]
Plexin-B1:Met [plasma membrane]
Other forms of this molecule
phospho-Met [plasma membrane]
phospho-Met [plasma membrane]
phospho-Met [plasma membrane]
phospho-Met [plasma membrane]
phospho-Met [plasma membrane]
phospho-Met [plasma membrane]
Inferred From
MET [plasma membrane] (Homo sapiens)
Cross References
ZINC - Substances
MET_MOUSE
ZINC target
P16056
PRO
P16056
ZINC - Predictions - Purchasable
MET_MOUSE
MGI
96969
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P35918 Kdr
3
Kdr [plasma membrane]
(R-MMU-195382)
Mouse Vegfr2-Human CSF1R fusion protein [plasma membrane]
(R-MMU-5218738)
phospho-Kdr [plasma membrane]
(R-MMU-4420103)
0.591
3
UniProt:P14210 HGF
5
HGF(495-728) [platelet alpha granule lumen]
(R-HSA-141764)
HGF(32-494) [platelet alpha granule lumen]
(R-HSA-139866)
pro-HGF [extracellular region]
(R-HSA-6800218)
HGF(495-728) [extracellular region]
(R-HSA-141767)
HGF(32-494) [extracellular region]
(R-HSA-56497)
0.558
2
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