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Basic fibroblast growth factor receptor 1 [plasma membrane]
Stable Identifier
R-MMU-420339
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
plasma membrane
Synonyms
Fgfr1, FGFR1_MOUSE
Locations in the PathwayBrowser for interactor UniProt:O35082
Expand all
Developmental Biology (Mus musculus)
Nervous system development (Mus musculus)
Axon guidance (Mus musculus)
L1CAM interactions (Mus musculus)
Signal transduction by L1 (Mus musculus)
L1-FGFR cis-heterodimerization (Mus musculus)
Basic fibroblast growth factor receptor 1 [plasma membrane] (Mus musculus)
Signal Transduction (Mus musculus)
Signaling by Receptor Tyrosine Kinases (Mus musculus)
Signaling by FGFR (Mus musculus)
Signaling by FGFR1 (Mus musculus)
FGFR1 ligand binding and activation (Mus musculus)
FGFR1c and Klotho ligand binding and activation (Mus musculus)
FGFR1c binds to Klotho-bound FGF23 (Mus musculus)
Basic fibroblast growth factor receptor 1 [plasma membrane] (Mus musculus)
FGFR1c ligand binding and activation (Mus musculus)
FGFR1c binds to FGF (Mus musculus)
Basic fibroblast growth factor receptor 1 [plasma membrane] (Mus musculus)
External Reference Information
External Reference
UniProt:P16092 Fgfr1
Gene Names
Fgfr1, Flg
Chain
signal peptide:1-21, chain:22-822
Reference Genes
BioGPS Gene:14182 Fgfr1
ENSEMBL:ENSMUSG00000031565.19 Fgfr1
KEGG Gene (Mus musculus):14182 Fgfr1
Monarch:14182 Fgfr1
NCBI Gene:14182 Fgfr1
UCSC:P16092 Fgfr1
Reference Transcript
RefSeq:XM_011242121.1 Fgfr1
RefSeq:NM_010206.3 Fgfr1
RefSeq:NM_001079908.2 Fgfr1
RefSeq:XM_006509010.2 Fgfr1
RefSeq:NM_001079909.2 Fgfr1
RefSeq:XM_006509012.1 Fgfr1
Other Identifiers
10570982
14182
1424050_s_at
1425911_a_at
1436551_at
17500108
4322453
4446912
4654147
4710897
4715504
4741317
4755293
4770585
4777523
4779741
4969419
4999827
5019455
5202052
5210884
5228863
5261908
5332521
5391172
5414655
5444292
5463968
5466199
5585364
5587337
5597520
97509_f_at
A_52_P136162
A_52_P552062
A_52_P668810
A_55_P1967015
A_55_P1967022
A_55_P2057777
A_55_P2506940
A_65_P11598
GE35402
GO:0000122
GO:0000166
GO:0000278
GO:0001525
GO:0001657
GO:0001701
GO:0001759
GO:0001837
GO:0002053
GO:0002062
GO:0003824
GO:0004672
GO:0004713
GO:0004714
GO:0005007
GO:0005102
GO:0005515
GO:0005524
GO:0005634
GO:0005737
GO:0005829
GO:0005886
GO:0006260
GO:0006351
GO:0006355
GO:0006468
GO:0006629
GO:0006766
GO:0007169
GO:0007420
GO:0007435
GO:0007605
GO:0008201
GO:0008283
GO:0008284
GO:0008543
GO:0010463
GO:0010467
GO:0010468
GO:0010629
GO:0010763
GO:0010863
GO:0010966
GO:0010976
GO:0012501
GO:0016020
GO:0016301
GO:0016310
GO:0016740
GO:0017134
GO:0018108
GO:0019827
GO:0021769
GO:0021837
GO:0021847
GO:0021954
GO:0023052
GO:0030031
GO:0030154
GO:0030324
GO:0030326
GO:0030901
GO:0031175
GO:0031410
GO:0031982
GO:0035607
GO:0036211
GO:0042127
GO:0042169
GO:0042472
GO:0042473
GO:0042474
GO:0042802
GO:0042803
GO:0043226
GO:0043235
GO:0043406
GO:0043410
GO:0043536
GO:0043583
GO:0044877
GO:0045597
GO:0045666
GO:0045668
GO:0045787
GO:0045944
GO:0046777
GO:0048339
GO:0048378
GO:0048469
GO:0048471
GO:0048513
GO:0048514
GO:0048699
GO:0048762
GO:0048856
GO:0048863
GO:0048870
GO:0050678
GO:0050839
GO:0050877
GO:0050886
GO:0051174
GO:0051897
GO:0055065
GO:0055074
GO:0060038
GO:0060045
GO:0060089
GO:0060117
GO:0060445
GO:0060484
GO:0060665
GO:0060979
GO:0070640
GO:0071344
GO:0071529
GO:0072089
GO:0072091
GO:0090080
GO:0090272
GO:0090722
GO:0140096
GO:1903465
GO:1904383
GO:1905564
GO:2000491
GO:2000546
GO:2000648
GO:2000830
GO:2001239
ILMN_2675581
ILMN_2727068
m33760_s_at
mMC019594
Participates
as an input of
L1-FGFR cis-heterodimerization (Mus musculus)
FGFR1c binds to FGF (Mus musculus)
FGFR1c binds to Klotho-bound FGF23 (Mus musculus)
as a component of
L1:FGFR1 [plasma membrane] (Mus musculus)
FGFR-1 homodimer [plasma membrane] (Mus musculus)
This entity regulates
Positively
Expression of Snai1 during gastrulation
(Mus musculus)
Expression of Tbx6 in paraxial mesoderm
(Mus musculus)
Other forms of this molecule
FGFR1b [plasma membrane]
phospho-p-8Y-FGFR1b [plasma membrane]
phospho-p-8Y-FGFR1c [plasma membrane]
Inferred From
FGFR1c [plasma membrane]
(Homo sapiens)
Cross References
RefSeq
XP_011240423.1
,
XP_006509075.1
,
XP_006509073.1
,
NP_001073377.1
,
NP_034336.2
,
NP_001073378.1
ZINC - Substances
FGFR1_MOUSE
ZINC target
P16092
Ensembl
ENSMUSP00000131343
,
ENSMUSG00000031565
,
ENSMUST00000117179
,
ENSMUST00000167764
,
ENSMUSP00000113909
,
ENSMUSP00000113855
,
ENSMUST00000084027
,
ENSMUSP00000081041
,
ENSMUST00000119398
PRO
P16092
ZINC - Predictions - Purchasable
FGFR1_MOUSE
MGI
95522
PDB
2CKN
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q99N32
1
Klb [plasma membrane]
(R-MMU-1307932)
0.576
3
UniProt:O35082
2
Kl [plasma membrane]
(R-MMU-190198)
Kl [extracellular region]
(R-MMU-190201)
0.499
2
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