Reactome | GRM5 [plasma membrane]

GRM5 [plasma membrane]

Stable Identifier

R-MMU-420553

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

plasma membrane

Synonyms

Q3UVX5

Locations in the PathwayBrowser

Expand all

Signal Transduction (Mus musculus)

- Signaling by GPCR (Mus musculus)
  - GPCR downstream signalling (Mus musculus)
    - G alpha (q) signalling events (Mus musculus)
      - Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
        
        Group I Metabotropic glutamate receptors:Glu [plasma membrane] (Mus musculus)
        
        GRM1,GRM5 [plasma membrane] (Mus musculus)
        
        GRM5 [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
        
        Group I Metabotropic glutamate receptors:Glu [plasma membrane] (Mus musculus)
        
        GRM1,GRM5 [plasma membrane] (Mus musculus)
        
        GRM5 [plasma membrane] (Mus musculus)
      - Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
        
        Group I Metabotropic glutamate receptors:Glu [plasma membrane] (Mus musculus)
        
        GRM1,GRM5 [plasma membrane] (Mus musculus)
        
        GRM5 [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
        
        Group I Metabotropic glutamate receptors:Glu [plasma membrane] (Mus musculus)
        
        GRM1,GRM5 [plasma membrane] (Mus musculus)
        
        GRM5 [plasma membrane] (Mus musculus)
      - The Ligand:GPCR:Gq complex dissociates (Mus musculus)
        
        GPCRs that activate Gq/11 [plasma membrane] (Mus musculus)
        
        GRM1,GRM5 [plasma membrane] (Mus musculus)
        
        GRM5 [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
        
        Group I Metabotropic glutamate receptors:Glu [plasma membrane] (Mus musculus)
        
        GRM1,GRM5 [plasma membrane] (Mus musculus)
        
        GRM5 [plasma membrane] (Mus musculus)
  - GPCR ligand binding (Mus musculus)
    - Class C/3 (Metabotropic glutamate/pheromone receptors) (Mus musculus)
      - Metabotropic glutamate receptors bind glutamate (Mus musculus)
        
        GRM1-8 [plasma membrane] (Mus musculus)
        
        GRM1,GRM5 [plasma membrane] (Mus musculus)
        
        GRM5 [plasma membrane] (Mus musculus)
        
        GRM1-8:L-Glu [plasma membrane] (Mus musculus)
        
        GRM1-8 [plasma membrane] (Mus musculus)
        
        GRM1,GRM5 [plasma membrane] (Mus musculus)
        
        GRM5 [plasma membrane] (Mus musculus)

External Reference Information

External Reference

UniProt:Q3UVX5

Reference Genes

BioGPS Gene:108071

ENSEMBL:ENSMUSG00000049583

KEGG Gene (Mus musculus):108071

Monarch:108071

NCBI Gene:108071

UCSC:Q3UVX5

Reference Transcript

Other Identifiers

10554778

105897_at

108071

1456119_at

17480002

203998

A_51_P465591

A_52_P181394

A_52_P675611

A_55_P2112464

ABS30420

AC113033

AC113115

AC116820

AC149088

AC163218

AK136840

B2BH30

BAE23144

CCDS52305

E9QMC2

EF508472

ENSMUSG00000049583

ENSMUSP00000114927

ENSMUST00000155358

ENSMUST00000155358.2

EntrezGene:108071

EntrezGene:Grm5

GE1520589

GO:0000185

GO:0001639

GO:0001932

GO:0002029

GO:0003674

GO:0004930

GO:0005515

GO:0005575

GO:0005622

GO:0005623

GO:0005737

GO:0005886

GO:0005887

GO:0006355

GO:0006412

GO:0006448

GO:0006464

GO:0006468

GO:0006810

GO:0007165

GO:0007186

GO:0007205

GO:0007206

GO:0007216

GO:0007267

GO:0007268

GO:0007568

GO:0007611

GO:0007612

GO:0007626

GO:0008066

GO:0008150

GO:0009058

GO:0014069

GO:0016020

GO:0016021

GO:0019899

GO:0030154

GO:0031687

GO:0034641

GO:0035584

GO:0040011

GO:0040013

GO:0042592

GO:0043005

GO:0043197

GO:0043198

GO:0043226

GO:0048169

GO:0048170

GO:0048856

GO:0050808

GO:0050877

GO:0050890

GO:0051966

GO:0055085

GO:0060078

GO:0061098

GO:0090647

GO:0097449

GO:0098685

GO:0098839

GO:0098978

GO:0099055

GO:0099170

GO:0099530

GO:0099553

GO:0099566

GO:0099583

GO:1902938

GO:1904646

GO:1990782

Grm5

Grm5-204

ILMN_1226905

ILMN_1242601

ILMN_1243437

ILMN_1248753

ILMN_2540719

ILMN_2540934

IPR000162

IPR000202

IPR000337

IPR001828

IPR011500

IPR017978

IPR017979

IPR019588

IPR028082

IPR038550

MGI:1351342

mMC022452

NM_001143834

NP_001137306

PF00003

PF01094

PF07562

PF10606

PR00248

PR00593

PR01055

SM01229

UPI00015C73E1

XM_006507184

XM_011241643

XP_006507247

XP_011239945

Participant Of

hasMember

GRM1,GRM5 [plasma membrane]

Inferred From

GRM5 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

XP_011239945.1, NP_001137306.1

ZINC - Substances

GRM5_MOUSE

ZINC target

Q3UVX5

PRO

Q3UVX5

ZINC - Predictions - Purchasable

GRM5_MOUSE

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q13526 PIN1	2	PIN1 [nucleoplasm] (R-HSA-936016) PIN1 [cytosol] (R-HSA-9626823)	0.544	2