Recruitment of Rnd1 to Plexin-A

Stable Identifier
R-MMU-421144
Type
Reaction [binding]
Species
Mus musculus
Compartment
cytosol, plasma membrane
ReviewStatus
5/5
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Recruitment of Rnd1 to Plexin-A
Binding of Sema3A to the Neuropilin-1-Plexin-A receptor complex results in the recruitment of Rnd1 to the cytoplasmic linker region of Plexin-A. Rnd1 activates the cytoplasmic GTPase signaling domain of Plexin-A.
Literature References
PubMed ID Title Journal Year
11784792 Antagonistic effects of Rnd1 and RhoD GTPases regulate receptor activity in Semaphorin 3A-induced cytoskeletal collapse

Rohm, B, Hovatta, I, Zanata, SM, Püschel, AW

J Neurosci 2002
19136556 Different requirement for Rnd GTPases of R-Ras GAP activity of Plexin-C1 and Plexin-D1

Katoh, H, Uesugi, K, Oinuma, I, Negishi, M

J Biol Chem 2009
Participants
Input
Output
Orthologous Events
Recruitment of Rnd1 to Plexin A (Homo sapiens)
Authored
Garapati, P V  (2009-03-23)
Reviewed
Kikutani, H  (2009-09-02)
Kumanogoh, A  (2009-09-02)
Created
Garapati, P V  (2009-05-15)
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