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G-protein alpha 13 [plasma membrane]
Stable Identifier
R-MMU-427849
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
plasma membrane
Synonyms
Guanine nucleotide-binding protein subunit alpha-13, Gna13, GNA13_MOUSE, Gna13
Locations in the PathwayBrowser
Expand all
Hemostasis (Mus musculus)
Platelet activation, signaling and aggregation (Mus musculus)
Signal amplification (Mus musculus)
Thromboxane signalling through TP receptor (Mus musculus)
Activated TP receptor binds G-protein G13 (Mus musculus)
Heterotrimeric G-protein G13 (inactive) [plasma membrane] (Mus musculus)
G-protein alpha (13):GDP [plasma membrane] (Mus musculus)
G-protein alpha 13 [plasma membrane] (Mus musculus)
TP receptor:Thromboxane A2:G-protein G13 (inactive) [plasma membrane] (Mus musculus)
Heterotrimeric G-protein G13 (inactive) [plasma membrane] (Mus musculus)
G-protein alpha (13):GDP [plasma membrane] (Mus musculus)
G-protein alpha 13 [plasma membrane] (Mus musculus)
Dissociation of the TP:G13 complex (Mus musculus)
G-protein alpha (13):GTP [plasma membrane] (Mus musculus)
G-protein alpha 13 [plasma membrane] (Mus musculus)
TP receptor:Thromboxane A2:G-protein G13 (active) [plasma membrane] (Mus musculus)
Heterotrimeric G-protein G13 (active) [plasma membrane] (Mus musculus)
G-protein alpha (13):GTP [plasma membrane] (Mus musculus)
G-protein alpha 13 [plasma membrane] (Mus musculus)
G13 activation by TP receptor (Mus musculus)
TP receptor:Thromboxane A2:G-protein G13 (active) [plasma membrane] (Mus musculus)
Heterotrimeric G-protein G13 (active) [plasma membrane] (Mus musculus)
G-protein alpha (13):GTP [plasma membrane] (Mus musculus)
G-protein alpha 13 [plasma membrane] (Mus musculus)
TP receptor:Thromboxane A2:G-protein G13 (inactive) [plasma membrane] (Mus musculus)
Heterotrimeric G-protein G13 (inactive) [plasma membrane] (Mus musculus)
G-protein alpha (13):GDP [plasma membrane] (Mus musculus)
G-protein alpha 13 [plasma membrane] (Mus musculus)
Thrombin signalling through proteinase activated receptors (PARs) (Mus musculus)
Thrombin-activated PARs activate G12/13 (Mus musculus)
Thrombin activated PAR:G12/13 (active) [plasma membrane] (Mus musculus)
G-protein G12/G13 (active) [plasma membrane] (Mus musculus)
Heterotrimeric G-protein G13 (active) [plasma membrane] (Mus musculus)
G-protein alpha (13):GTP [plasma membrane] (Mus musculus)
G-protein alpha 13 [plasma membrane] (Mus musculus)
Thrombin activated PAR:G12/13 (inactive) [plasma membrane] (Mus musculus)
G-protein G12/G13 (inactive) [plasma membrane] (Mus musculus)
Heterotrimeric G-protein G13 (inactive) [plasma membrane] (Mus musculus)
G-protein alpha (13):GDP [plasma membrane] (Mus musculus)
G-protein alpha 13 [plasma membrane] (Mus musculus)
Thrombin-activated PARs:G12/13 (active) dissociate (Mus musculus)
G-protein alpha (12/13):GTP [plasma membrane] (Mus musculus)
G-protein alpha (13):GTP [plasma membrane] (Mus musculus)
G-protein alpha 13 [plasma membrane] (Mus musculus)
Thrombin activated PAR:G12/13 (active) [plasma membrane] (Mus musculus)
G-protein G12/G13 (active) [plasma membrane] (Mus musculus)
Heterotrimeric G-protein G13 (active) [plasma membrane] (Mus musculus)
G-protein alpha (13):GTP [plasma membrane] (Mus musculus)
G-protein alpha 13 [plasma membrane] (Mus musculus)
Signal Transduction (Mus musculus)
Death Receptor Signaling (Mus musculus)
p75 NTR receptor-mediated signalling (Mus musculus)
Cell death signalling via NRAGE, NRIF and NADE (Mus musculus)
NRAGE signals death through JNK (Mus musculus)
p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor (Mus musculus)
GEFs [cytosol] (Mus musculus)
G13-activated p115-RhoGEF [plasma membrane] (Mus musculus)
G-protein alpha (13):GTP [plasma membrane] (Mus musculus)
G-protein alpha 13 [plasma membrane] (Mus musculus)
Signaling by GPCR (Mus musculus)
GPCR downstream signalling (Mus musculus)
G alpha (12/13) signalling events (Mus musculus)
G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP (Mus musculus)
G-protein alpha (12/13):GDP [plasma membrane] (Mus musculus)
G-protein alpha (13):GDP [plasma membrane] (Mus musculus)
G-protein alpha 13 [plasma membrane] (Mus musculus)
G-protein alpha (12/13):GTP [plasma membrane] (Mus musculus)
G-protein alpha (13):GTP [plasma membrane] (Mus musculus)
G-protein alpha 13 [plasma membrane] (Mus musculus)
G alpha (13) activates Rho guanine nucleotide exchange factor 1 (p115-RhoGEF) (Mus musculus)
G-protein alpha (13):GTP [plasma membrane] (Mus musculus)
G-protein alpha 13 [plasma membrane] (Mus musculus)
G13-activated p115-RhoGEF [plasma membrane] (Mus musculus)
G-protein alpha (13):GTP [plasma membrane] (Mus musculus)
G-protein alpha 13 [plasma membrane] (Mus musculus)
GEFs activate RhoA,B,C (Mus musculus)
GEFs [cytosol] (Mus musculus)
G13-activated p115-RhoGEF [plasma membrane] (Mus musculus)
G-protein alpha (13):GTP [plasma membrane] (Mus musculus)
G-protein alpha 13 [plasma membrane] (Mus musculus)
Inactive G alpha (12/13) reassociates with G beta:gamma (Mus musculus)
G-protein G12/G13 (inactive) [plasma membrane] (Mus musculus)
Heterotrimeric G-protein G13 (inactive) [plasma membrane] (Mus musculus)
G-protein alpha (13):GDP [plasma membrane] (Mus musculus)
G-protein alpha 13 [plasma membrane] (Mus musculus)
G-protein alpha (12/13):GDP [plasma membrane] (Mus musculus)
G-protein alpha (13):GDP [plasma membrane] (Mus musculus)
G-protein alpha 13 [plasma membrane] (Mus musculus)
LARG activation by G alpha 12/13 (Mus musculus)
G-protein alpha (12/13):GTP [plasma membrane] (Mus musculus)
G-protein alpha (13):GTP [plasma membrane] (Mus musculus)
G-protein alpha 13 [plasma membrane] (Mus musculus)
G-protein alpha (12/13):LARG [plasma membrane] (Mus musculus)
G-protein alpha (12/13):GTP [plasma membrane] (Mus musculus)
G-protein alpha (13):GTP [plasma membrane] (Mus musculus)
G-protein alpha 13 [plasma membrane] (Mus musculus)
LARG binds plexin B1 (Mus musculus)
G-protein alpha (12/13):LARG [plasma membrane] (Mus musculus)
G-protein alpha (12/13):GTP [plasma membrane] (Mus musculus)
G-protein alpha (13):GTP [plasma membrane] (Mus musculus)
G-protein alpha 13 [plasma membrane] (Mus musculus)
G-protein alpha (12/13):LARG:Plexin B1 [plasma membrane] (Mus musculus)
G-protein alpha (12/13):LARG [plasma membrane] (Mus musculus)
G-protein alpha (12/13):GTP [plasma membrane] (Mus musculus)
G-protein alpha (13):GTP [plasma membrane] (Mus musculus)
G-protein alpha 13 [plasma membrane] (Mus musculus)
Liganded G12/13-activating GPCR acts as a GEF for G12/13 (Mus musculus)
Ligand:GPCR complexes that activate G12/13:Heterotrimeric G-protein G12/13 (active). [plasma membrane] (Mus musculus)
G-protein G12/G13 (active) [plasma membrane] (Mus musculus)
Heterotrimeric G-protein G13 (active) [plasma membrane] (Mus musculus)
G-protein alpha (13):GTP [plasma membrane] (Mus musculus)
G-protein alpha 13 [plasma membrane] (Mus musculus)
Ligand:GPCR complexes that activate G12/13:Heterotrimeric G-protein G12/13 (inactive). [plasma membrane] (Mus musculus)
G-protein G12/G13 (inactive) [plasma membrane] (Mus musculus)
Heterotrimeric G-protein G13 (inactive) [plasma membrane] (Mus musculus)
G-protein alpha (13):GDP [plasma membrane] (Mus musculus)
G-protein alpha 13 [plasma membrane] (Mus musculus)
Liganded G12/13-activating GPCRs bind inactive heterotrimeric G-protein G12/13 (Mus musculus)
G-protein G12/G13 (inactive) [plasma membrane] (Mus musculus)
Heterotrimeric G-protein G13 (inactive) [plasma membrane] (Mus musculus)
G-protein alpha (13):GDP [plasma membrane] (Mus musculus)
G-protein alpha 13 [plasma membrane] (Mus musculus)
Ligand:GPCR complexes that activate G12/13:Heterotrimeric G-protein G12/13 (inactive). [plasma membrane] (Mus musculus)
G-protein G12/G13 (inactive) [plasma membrane] (Mus musculus)
Heterotrimeric G-protein G13 (inactive) [plasma membrane] (Mus musculus)
G-protein alpha (13):GDP [plasma membrane] (Mus musculus)
G-protein alpha 13 [plasma membrane] (Mus musculus)
The Ligand:GPCR:G12/13 complex dissociates (Mus musculus)
G-protein alpha (12/13):GTP [plasma membrane] (Mus musculus)
G-protein alpha (13):GTP [plasma membrane] (Mus musculus)
G-protein alpha 13 [plasma membrane] (Mus musculus)
Ligand:GPCR complexes that activate G12/13:Heterotrimeric G-protein G12/13 (active). [plasma membrane] (Mus musculus)
G-protein G12/G13 (active) [plasma membrane] (Mus musculus)
Heterotrimeric G-protein G13 (active) [plasma membrane] (Mus musculus)
G-protein alpha (13):GTP [plasma membrane] (Mus musculus)
G-protein alpha 13 [plasma membrane] (Mus musculus)
p115-RhoGEF activation of RHOA (Mus musculus)
G13-activated p115-RhoGEF [plasma membrane] (Mus musculus)
G-protein alpha (13):GTP [plasma membrane] (Mus musculus)
G-protein alpha 13 [plasma membrane] (Mus musculus)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Mus musculus)
Signaling by Rho GTPases (Mus musculus)
RHO GTPase cycle (Mus musculus)
CDC42 GTPase cycle (Mus musculus)
CDC42 GEFs activate CDC42 (Mus musculus)
CDC42 GEFs [cytosol] (Mus musculus)
G-protein alpha 13 [plasma membrane] (Mus musculus)
RAC1 GTPase cycle (Mus musculus)
RAC1 GEFs activate RAC1 (Mus musculus)
RAC1 GEFs [cytosol] (Mus musculus)
G-protein alpha 13 [plasma membrane] (Mus musculus)
External Reference Information
External Reference
UniProt:P27601 Gna13
Gene Names
Gna13, Gna-13
Chain
chain:1-377
Reference Genes
BioGPS Gene:14674 Gna13
ENSEMBL:ENSMUSG00000020611.15 Gna13
KEGG Gene (Mus musculus):14674 Gna13
Monarch:14674 Gna13
NCBI Gene:14674 Gna13
UCSC:P27601 Gna13
Reference Transcript
RefSeq:NM_010303.3 Gna13
Other Identifiers
100514_at
10382243
104316_at
1422555_s_at
1422556_at
1433749_at
1450656_at
1453470_a_at
1460317_s_at
14674
17257822
4436434
4482242
4601984
4642025
4745795
5007852
5054922
5308859
5313242
5481245
A_51_P286563
A_51_P501710
A_55_P2041784
GE35475
GO:0000166
GO:0001525
GO:0001569
GO:0001664
GO:0001701
GO:0003013
GO:0003824
GO:0003924
GO:0005515
GO:0005525
GO:0005634
GO:0005737
GO:0005829
GO:0005834
GO:0005886
GO:0007165
GO:0007186
GO:0007188
GO:0007189
GO:0007204
GO:0007266
GO:0008217
GO:0008360
GO:0010762
GO:0016020
GO:0016787
GO:0019001
GO:0023052
GO:0030154
GO:0030168
GO:0031410
GO:0031526
GO:0031683
GO:0031752
GO:0035556
GO:0042060
GO:0042470
GO:0043226
GO:0046872
GO:0048856
GO:0048870
GO:1904706
GO:1904753
ILMN_1248827
ILMN_2754253
M63660_s_at
mMC003346
Participates
as a candidate of
CDC42 GEFs [cytosol] (Mus musculus)
as a member of
RAC1 GEFs [cytosol] (Mus musculus)
as a component of
G-protein alpha (13):GDP [plasma membrane] (Mus musculus)
G-protein alpha (13):GTP [plasma membrane] (Mus musculus)
Inferred From
GNA13 [plasma membrane]
(Homo sapiens)
Cross References
RefSeq
NP_034433.3
Ensembl
ENSMUSG00000020611
,
ENSMUST00000020930
,
ENSMUSP00000020930
PRO
P27601
MGI
95768
PDB
1SHZ
,
3CX7
,
3AB3
,
1ZCB
,
3CX8
,
3CX6
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