Reactome: A Curated Pathway Database

Thrombin-activated PAR binds G-protein G12/13

Stable Identifier
R-MMU-427858
Type
Reaction
Species
Mus musculus
Compartment
Summation

Thrombin receptors activate G-proteins in the G12/13 family. Gq knockout mice exhibit defective platelet activation, but retain shape change responses to thrombin, mediated by G12/13.

Literature References
Participants
Orthologous Events