Reactome | Itgb1 [plasma membrane]

Itgb1 [plasma membrane]

Stable Identifier

R-MMU-434908

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

plasma membrane

Synonyms

Integrin beta-1, ITB1_MOUSE

Locations in the PathwayBrowser

Expand all

Signal Transduction (Mus musculus)

- Signaling by Receptor Tyrosine Kinases (Mus musculus)
  - Signaling by MET (Mus musculus)
    - MET promotes cell motility (Mus musculus)
      - MET activates PTK2 signaling (Mus musculus)
        
        PTK2 binds activated MET (Mus musculus)
        
        Integrin alpha2beta1,alpha3:beta1:(collagen,laminin,fibronectin) [plasma membrane] (Mus musculus)
        
        Integrin alpha2beta1,alpha3beta1 [plasma membrane] (Mus musculus)
        
        Integrin alpha2beta1 [plasma membrane] (Mus musculus)
        
        Itgb1 [plasma membrane] (Mus musculus)
        
        Integrin alpha3beta1 [plasma membrane] (Mus musculus)
        
        Itgb1 [plasma membrane] (Mus musculus)
      - MET interacts with TNS proteins (Mus musculus)
        
        MET binds TNS4 (Mus musculus)
        
        HGF:p-4Y-MET dimer:TNS4:ITGB1 [plasma membrane] (Mus musculus)
        
        TNS4:ITGB1 [plasma membrane] (Mus musculus)
        
        Itgb1 [plasma membrane] (Mus musculus)
        
        TNS4:ITGB1 [plasma membrane] (Mus musculus)
        
        Itgb1 [plasma membrane] (Mus musculus)

External Reference Information

External Reference

UniProt:P09055 Itgb1

Gene Names

Itgb1

Chain

signal peptide:1-20, chain:21-798

Reference Genes

BioGPS Gene:16412 Itgb1

ENSEMBL:ENSMUSG00000025809 Itgb1

KEGG Gene (Mus musculus):16412 Itgb1

Monarch:16412 Itgb1

NCBI Gene:16412 Itgb1

UCSC:P09055 Itgb1

Reference Transcript

RefSeq:NM_010578.2 Itgb1

Other Identifiers

100123_f_at

100124_r_at

10576661

115696_at

1426918_at

1426919_at

1426920_x_at

1452545_a_at

16412

17507014

4449544

4585311

4703526

4735776

4754301

4872369

4938074

5004059

5004789

5071611

5103062

5116478

5126299

5279453

5312931

5345263

5353565

5357708

5422658

5437814

5513544

5562193

5607271

A_51_P286527

A_52_P351816

A_66_P113059

GE42898

GO:0000003

GO:0000082

GO:0000132

GO:0000278

GO:0000902

GO:0001669

GO:0001701

GO:0001708

GO:0001726

GO:0001894

GO:0001968

GO:0002020

GO:0002042

GO:0002376

GO:0003674

GO:0003779

GO:0005102

GO:0005178

GO:0005515

GO:0005518

GO:0005575

GO:0005576

GO:0005604

GO:0005622

GO:0005737

GO:0005768

GO:0005886

GO:0005911

GO:0005912

GO:0005925

GO:0006464

GO:0006810

GO:0006909

GO:0006950

GO:0007010

GO:0007049

GO:0007155

GO:0007159

GO:0007160

GO:0007161

GO:0007165

GO:0007229

GO:0007267

GO:0008092

GO:0008150

GO:0008219

GO:0008277

GO:0008283

GO:0008284

GO:0008285

GO:0008305

GO:0008354

GO:0008542

GO:0009056

GO:0009790

GO:0009897

GO:0009986

GO:0010710

GO:0010763

GO:0010811

GO:0010976

GO:0014704

GO:0015031

GO:0016020

GO:0016021

GO:0016192

GO:0016477

GO:0019899

GO:0019900

GO:0019901

GO:0019904

GO:0019960

GO:0021943

GO:0022607

GO:0023035

GO:0030027

GO:0030030

GO:0030032

GO:0030054

GO:0030056

GO:0030154

GO:0030175

GO:0030198

GO:0030335

GO:0031012

GO:0031175

GO:0031345

GO:0031410

GO:0031589

GO:0031594

GO:0031623

GO:0032587

GO:0032594

GO:0032991

GO:0033627

GO:0033631

GO:0034113

GO:0034330

GO:0034665

GO:0034666

GO:0034667

GO:0034674

GO:0034677

GO:0034679

GO:0034680

GO:0034681

GO:0035024

GO:0035748

GO:0038023

GO:0040007

GO:0040011

GO:0042383

GO:0042470

GO:0042592

GO:0042995

GO:0043065

GO:0043066

GO:0043167

GO:0043197

GO:0043226

GO:0043235

GO:0043236

GO:0043547

GO:0044877

GO:0045121

GO:0045202

GO:0045211

GO:0045214

GO:0045596

GO:0045665

GO:0045666

GO:0045766

GO:0045807

GO:0046872

GO:0046982

GO:0048333

GO:0048471

GO:0048646

GO:0048675

GO:0048813

GO:0048856

GO:0048870

GO:0050731

GO:0050839

GO:0050877

GO:0050901

GO:0051393

GO:0051726

GO:0051897

GO:0051951

GO:0055007

GO:0055037

GO:0055085

GO:0061024

GO:0070830

GO:0071404

GO:0071438

GO:0071711

GO:0090303

GO:0097060

GO:0097386

GO:0098639

GO:0098978

GO:0099055

GO:0099699

GO:0150003

GO:0150103

GO:1901979

GO:1903078

GO:1990782

GO:2000273

GO:2000811

ILMN_2609304

ILMN_2721771

ILMN_2789077

mMC007548

y00769_s_at

Participant Of

hasComponent

input

ILK interacts with beta-1 integrin

Inferred From

ITGB1 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_034708.1

Target Pathogen

5b354852be737e166372eba8

Ensembl

ENSMUST00000090006, ENSMUSP00000087457, ENSMUSG00000025809

PRO

P09055

MGI

96610

PDB

5XQ0

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q91YD9 Wasl	5	Wasl [plasma membrane] (R-MMU-203010) Wasl [endocytic vesicle membrane] (R-MMU-535012) N-Wasp [cytosol] (R-MMU-2029073) Wasl [cytosol] (R-MMU-201873) phospho-Wasl [cytosol] (R-MMU-2197672)	0.499	2

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