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Nedd8 [cytosol]
Stable Identifier
R-MMU-4419895
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
cytosol
Synonyms
C111-AcM-UBE2M-G76-NEDD8, P29595
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Mus musculus)
Post-translational protein modification (Mus musculus)
Neddylation (Mus musculus)
AcM-UBE2M transfers NEDD8 to CRL1 E3 ubiquitin ligase complex (Mus musculus)
NEDD8-AcM-UBE2M:CRL1 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Mus musculus)
NEDD8-AcM-UBE2M [cytosol] (Mus musculus)
Nedd8 [cytosol] (Mus musculus)
AcM-UBE2M transfers NEDD8 to CRL2 E3 ubiquitin ligase complex (Mus musculus)
NEDD8-AcM-UBE2M:CRL2 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Mus musculus)
NEDD8-AcM-UBE2M [cytosol] (Mus musculus)
Nedd8 [cytosol] (Mus musculus)
AcM-UBE2M transfers NEDD8 to CRL3 E3 ubiquitin ligase complex (Mus musculus)
NEDD8-AcM-UBE2M:CRL3 E3 ubiquitin ligase :DCUN1D1,2,4,5 [cytosol] (Mus musculus)
NEDD8-AcM-UBE2M [cytosol] (Mus musculus)
Nedd8 [cytosol] (Mus musculus)
NEDD8:AcM-UBE2M binds CRL1 E3 ubiquitin ligase complex (Mus musculus)
NEDD8-AcM-UBE2M [cytosol] (Mus musculus)
Nedd8 [cytosol] (Mus musculus)
NEDD8-AcM-UBE2M:CRL1 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Mus musculus)
NEDD8-AcM-UBE2M [cytosol] (Mus musculus)
Nedd8 [cytosol] (Mus musculus)
NEDD8:AcM-UBE2M binds CRL2 E3 ubiquitin ligase complex (Mus musculus)
NEDD8-AcM-UBE2M [cytosol] (Mus musculus)
Nedd8 [cytosol] (Mus musculus)
NEDD8-AcM-UBE2M:CRL2 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Mus musculus)
NEDD8-AcM-UBE2M [cytosol] (Mus musculus)
Nedd8 [cytosol] (Mus musculus)
NEDD8:AcM-UBE2M binds CRL3 E3 ubiquitin ligase complex (Mus musculus)
NEDD8-AcM-UBE2M [cytosol] (Mus musculus)
Nedd8 [cytosol] (Mus musculus)
NEDD8-AcM-UBE2M:CRL3 E3 ubiquitin ligase :DCUN1D1,2,4,5 [cytosol] (Mus musculus)
NEDD8-AcM-UBE2M [cytosol] (Mus musculus)
Nedd8 [cytosol] (Mus musculus)
Transfer of NEDD8 to AcM-UBE2M (Mus musculus)
NEDD8-AcM-UBE2M [cytosol] (Mus musculus)
Nedd8 [cytosol] (Mus musculus)
Signal Transduction (Mus musculus)
Signaling by TGFB family members (Mus musculus)
Signaling by TGF-beta Receptor Complex (Mus musculus)
TGF-beta receptor signaling activates SMADs (Mus musculus)
CBL neddylates TGFBR2 (Mus musculus)
NEDD8-AcM-UBE2M [cytosol] (Mus musculus)
Nedd8 [cytosol] (Mus musculus)
External Reference Information
External Reference
UniProt:P29595
Gene Names
Nedd8
Reference Genes
BioGPS Gene:18002 Nedd8
ENSEMBL:ENSMUSG00000010376
KEGG:mmu:18002 Nedd8
Monarch:18002 Nedd8
NCBI Gene:18002 Nedd8
UCSC:P29595 Nedd8
Reference Transcript
RefSeq:NM_008683.3 Nedd8
Other Identifiers
10420089
1423715_a_at
17306785
18002
4364239
4465089
4551746
4750421
4852160
4939901
5098694
5276655
5481791
5601036
93519_s_at
A_51_P416869
D10918_s_at
GE34086
GO:0005515
GO:0005634
GO:0005654
GO:0005737
GO:0005829
GO:0006355
GO:0006357
GO:0008104
GO:0014070
GO:0019941
GO:0030162
GO:0031386
GO:0031625
GO:0043226
GO:0045116
GO:0098978
GO:0150052
ILMN_1256971
Msa.2767.0_f_at
Msa.5174.0_s_at
mMC004214
Participates
as a component of
NEDD8-AcM-UBE2M [cytosol] (Mus musculus)
Other forms of this molecule
Nedd8 [nucleoplasm]
Nedd8 [nucleoplasm]
Nedd8 [cytosol]
Nedd8 [cytosol]
Nedd8 [cytosol]
Nedd8 [cytosol]
Nedd8 [cytosol]
Inferred From
C111-AcM-UBE2M-G76-NEDD8 [cytosol]
(Homo sapiens)
Modified Residues
Name
Inter-chain Crosslink via S-(glycyl)-L-cysteine (Cys-Gly) at 76 and 111 (in Homo sapiens)
Coordinate
76
PsiMod Name
S-(glycyl)-L-cysteine (Cys-Gly)
PsiMod Definition
A protein modification that effectively crosslinks an L-cysteine residue and a glycine residue by a thioester bond to form S-glycyl-L-cysteine.
Cross References
RefSeq
NP_032709.1
ENSEMBL
ENSMUST00000010520
,
ENSMUSP00000010520
PRO
P29595
MGI
97301
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:A0A0F6B423 A0A0F6B423
0.499
2
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