Syk binds Vav2

Stable Identifier
R-MMU-442289
Type
Reaction [binding]
Species
Mus musculus
Compartment
General
SVG |   | PPTX  | SBGN
Syk binds Vav2

Constructs containing the C-terminal SH3-SH2-SH3 domain of Vav2 interact with Syk. An SH2-inactivating point mutation (R688Q) abolishes the interaction.

Literature References
PubMed ID Title Journal Year
11262396 Vav2 activates c-fos serum response element and CD69 expression but negatively regulates nuclear factor of activated T cells and interleukin-2 gene activation in T lymphocyte

Tartare-Deckert, S, Monthouel, MN, Charvet, C, Foucault, I, Van Obberghen, E, Bernard, A, Altman, A, Deckert, M

J Biol Chem 2001
Participants
Orthologous Events
Authored
Reviewed
Created