Interaction of L1 with Laminin-1

Stable Identifier
R-MMU-443785
Type
Reaction [binding]
Species
Mus musculus
Compartment
General
SVG |   | PPTX  | SBGN
Interaction of L1 with Laminin-1

While HNK-1 (human natural killer 1) carbohydrate is expressed on several kinds of cell adhesion molecules in the nervous system, L1CAM is the major carrier of HNK-1 carbohydrate. HNK-1 also functions as a ligand for Laminin. L1 binds in a concentration-dependent and saturating manner to Laminin in presence of HNK-1.

Literature References
PubMed ID Title Journal Year
18024472 Expression and function of the HNK-1 carbohydrate

Morita, I, Kizuka, Y, Kakuda, S, Oka, S

J Biochem 2008
9003039 L1/HNK-1 carbohydrate- and beta 1 integrin-dependent neural cell adhesion to laminin-1

Hall, H, Carbonetto, S, Schachner, M

J Neurochem 1997
Participants
Orthologous Events
Authored
Reviewed
Created