Reactome | Gpr132 [plasma membrane]

Gpr132 [plasma membrane]

Stable Identifier

R-MMU-444699

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

plasma membrane

Synonyms

GPR132, Q9Z282

Locations in the PathwayBrowser

Expand all

Signal Transduction (Mus musculus)

- Signaling by GPCR (Mus musculus)
  - GPCR downstream signalling (Mus musculus)
    - G alpha (q) signalling events (Mus musculus)
      - Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
        
        pH sensing receptors:H+ [plasma membrane] (Mus musculus)
        
        pH sensing receptors [plasma membrane] (Mus musculus)
        
        Gpr132 [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
        
        pH sensing receptors:H+ [plasma membrane] (Mus musculus)
        
        pH sensing receptors [plasma membrane] (Mus musculus)
        
        Gpr132 [plasma membrane] (Mus musculus)
      - Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
        
        pH sensing receptors:H+ [plasma membrane] (Mus musculus)
        
        pH sensing receptors [plasma membrane] (Mus musculus)
        
        Gpr132 [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
        
        pH sensing receptors:H+ [plasma membrane] (Mus musculus)
        
        pH sensing receptors [plasma membrane] (Mus musculus)
        
        Gpr132 [plasma membrane] (Mus musculus)
      - The Ligand:GPCR:Gq complex dissociates (Mus musculus)
        
        GPCRs that activate Gq/11 [plasma membrane] (Mus musculus)
        
        pH sensing receptors [plasma membrane] (Mus musculus)
        
        Gpr132 [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
        
        pH sensing receptors:H+ [plasma membrane] (Mus musculus)
        
        pH sensing receptors [plasma membrane] (Mus musculus)
        
        Gpr132 [plasma membrane] (Mus musculus)
  - GPCR ligand binding (Mus musculus)
    - Class A/1 (Rhodopsin-like receptors) (Mus musculus)
      - GPR4, GPR65, GPR132 and OGR1 are pH sensing receptors (Mus musculus)
        
        pH sensing receptors [plasma membrane] (Mus musculus)
        
        Gpr132 [plasma membrane] (Mus musculus)
        
        pH sensing receptors:H+ [plasma membrane] (Mus musculus)
        
        pH sensing receptors [plasma membrane] (Mus musculus)
        
        Gpr132 [plasma membrane] (Mus musculus)

External Reference Information

External Reference

UniProt:Q9Z282

Gene Names

Gpr132

Reference Genes

BioGPS Gene:56696 Gpr132

ENSEMBL:ENSMUSG00000021298

ENSEMBL:ENSMUSG00000021298.9 Gpr132

KEGG Gene (Mus musculus):56696 Gpr132

Monarch:56696 Gpr132

NCBI Gene:56696 Gpr132

UCSC:Q9Z282 Gpr132

Reference Transcript

Other Identifiers

10402800

1421755_at

1444233_at

17284247

4794629

4855016

5002782

5052195

5455699

56696

94566_at

A_51_P177340

A_55_P2051229

GE37666

GO:0000082

GO:0000278

GO:0004930

GO:0005886

GO:0007165

GO:0007186

GO:0010972

GO:0016020

GO:0023052

GO:0060089

ILMN_2659578

mMC019172

Participates

as a member of

pH sensing receptors [plasma membrane] (Mus musculus)

Inferred From

GPR132 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_064309.1, XP_006516166.1, XP_006516165.1

Ensembl

ENSMUSP00000021729, ENSMUST00000021729, ENSMUSG00000021298

PRO

Q9Z282

MGI

1890220