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PAK1 dimer [cytosol]
Stable Identifier
R-MMU-445002
Type
Complex
Species
Mus musculus
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Developmental Biology (Mus musculus)
Nervous system development (Mus musculus)
Axon guidance (Mus musculus)
EPH-Ephrin signaling (Mus musculus)
EPHB-mediated forward signaling (Mus musculus)
PAK1 binds RAC1:GTP (Mus musculus)
PAK1 dimer [cytosol] (Mus musculus)
L1CAM interactions (Mus musculus)
Signal transduction by L1 (Mus musculus)
Interaction of PAK1 with Rac1-GTP (Mus musculus)
PAK1 dimer [cytosol] (Mus musculus)
Semaphorin interactions (Mus musculus)
Sema3A PAK dependent Axon repulsion (Mus musculus)
Activation of PAK by Rac1 (Mus musculus)
PAK1,2,3 dimer [cytosol] (Mus musculus)
PAK1 dimer [cytosol] (Mus musculus)
Immune System (Mus musculus)
Adaptive Immune System (Mus musculus)
Costimulation by the CD28 family (Mus musculus)
CD28 co-stimulation (Mus musculus)
CD28 dependent Vav1 pathway (Mus musculus)
Activation of PAKs by RAC1 and CDC42 (Mus musculus)
PAK1,2,3 dimer [cytosol] (Mus musculus)
PAK1 dimer [cytosol] (Mus musculus)
Innate Immune System (Mus musculus)
Fc epsilon receptor (FCERI) signaling (Mus musculus)
FCERI mediated MAPK activation (Mus musculus)
Autophosphorylation of PAK (Mus musculus)
PAK dimer [cytosol] (Mus musculus)
PAK1 dimer [cytosol] (Mus musculus)
p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV:RAC1-GTP:PAK dimer [plasma membrane] (Mus musculus)
PAK dimer [cytosol] (Mus musculus)
PAK1 dimer [cytosol] (Mus musculus)
Recruitment of PAK to the membrane by binding active RAC1 (Mus musculus)
PAK dimer [cytosol] (Mus musculus)
PAK1 dimer [cytosol] (Mus musculus)
p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV:RAC1-GTP:PAK dimer [plasma membrane] (Mus musculus)
PAK dimer [cytosol] (Mus musculus)
PAK1 dimer [cytosol] (Mus musculus)
Fcgamma receptor (FCGR) dependent phagocytosis (Mus musculus)
Regulation of actin dynamics for phagocytic cup formation (Mus musculus)
RAC1 and CDC42 activate PAK1 (Mus musculus)
PAK1 dimer [cytosol] (Mus musculus)
Signal Transduction (Mus musculus)
MAPK family signaling cascades (Mus musculus)
MAPK6/MAPK4 signaling (Mus musculus)
Activation of PAKs by RAC1 and CDC42 (Mus musculus)
PAK1,2,3 dimer [cytosol] (Mus musculus)
PAK1 dimer [cytosol] (Mus musculus)
Signaling by Receptor Tyrosine Kinases (Mus musculus)
Signaling by VEGF (Mus musculus)
VEGFA-VEGFR2 Pathway (Mus musculus)
VEGFR2 mediated vascular permeability (Mus musculus)
PAK1-3 autophosphorylates (Mus musculus)
PAK1,2,3 dimer [cytosol] (Mus musculus)
PAK1 dimer [cytosol] (Mus musculus)
PAK1-3 dimer disassociates (Mus musculus)
2 x p-VAV family:PIP3:RAC1:GTP:PAK 1-3 [plasma membrane] (Mus musculus)
PAK1,2,3 dimer [cytosol] (Mus musculus)
PAK1 dimer [cytosol] (Mus musculus)
RAC1 binds PAK1-3 (Mus musculus)
2 x p-VAV family:PIP3:RAC1:GTP:PAK 1-3 [plasma membrane] (Mus musculus)
PAK1,2,3 dimer [cytosol] (Mus musculus)
PAK1 dimer [cytosol] (Mus musculus)
PAK1,2,3 dimer [cytosol] (Mus musculus)
PAK1 dimer [cytosol] (Mus musculus)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Mus musculus)
Signaling by Rho GTPases (Mus musculus)
RHO GTPase Effectors (Mus musculus)
RHO GTPases activate PAKs (Mus musculus)
NF2 binds PAK1 (Mus musculus)
PAK1 dimer [cytosol] (Mus musculus)
PAK1:NF2 [plasma membrane] (Mus musculus)
PAK1 dimer [cytosol] (Mus musculus)
RAC1 and CDC42 activate PAK1 (Mus musculus)
PAK1 dimer [cytosol] (Mus musculus)
RHO GTPase cycle (Mus musculus)
RAC1 GTPase cycle (Mus musculus)
RAC1 binds effectors at the plasma membrane (Mus musculus)
RAC1 effectors [cytosol] (Mus musculus)
PAK1 dimer [cytosol] (Mus musculus)
RAC1:GTP:RAC1 effectors [plasma membrane] (Mus musculus)
RAC1 effectors [cytosol] (Mus musculus)
PAK1 dimer [cytosol] (Mus musculus)
RAC2 GTPase cycle (Mus musculus)
RAC2 binds effectors at the plasma membrane (Mus musculus)
RAC2 plasma membrane effectors [cytosol] (Mus musculus)
PAK1 dimer [cytosol] (Mus musculus)
RAC2:GTP:RAC2 cytosolic effectors [plasma membrane] (Mus musculus)
RAC2 plasma membrane effectors [cytosol] (Mus musculus)
PAK1 dimer [cytosol] (Mus musculus)
RAC3 GTPase cycle (Mus musculus)
RAC3 binds effectors at the plasma membrane (Mus musculus)
RAC3 effectors [cytosol] (Mus musculus)
PAK1 dimer [cytosol] (Mus musculus)
RAC3:GTP:RAC3 effectors [plasma membrane] (Mus musculus)
RAC3 effectors [cytosol] (Mus musculus)
PAK1 dimer [cytosol] (Mus musculus)
RHOH GTPase cycle (Mus musculus)
RHOH binds effectors at the plasma membrane (Mus musculus)
RHOH effectors [cytosol] (Mus musculus)
PAK1 dimer [cytosol] (Mus musculus)
RHOH:GTP:RHOH effectors [plasma membrane] (Mus musculus)
RHOH effectors [cytosol] (Mus musculus)
PAK1 dimer [cytosol] (Mus musculus)
RHOQ GTPase cycle (Mus musculus)
RHOQ binds effectors at the plasma membrane (Mus musculus)
RHOQ effectors [cytosol] (Mus musculus)
PAK1 dimer [cytosol] (Mus musculus)
RHOQ:GTP:RHOQ effectors [plasma membrane] (Mus musculus)
RHOQ effectors [cytosol] (Mus musculus)
PAK1 dimer [cytosol] (Mus musculus)
RHOU GTPase cycle (Mus musculus)
RHOU binds effectors at the plasma membrane (Mus musculus)
RHOU effectors [cytosol] (Mus musculus)
PAK1 dimer [cytosol] (Mus musculus)
RHOU:GTP:RHOU effectors [plasma membrane] (Mus musculus)
RHOU effectors [cytosol] (Mus musculus)
PAK1 dimer [cytosol] (Mus musculus)
RHOV GTPase cycle (Mus musculus)
RHOV binds effectors at the plasma membrane (Mus musculus)
RHOV effectors [cytosol] (Mus musculus)
PAK1 dimer [cytosol] (Mus musculus)
RHOV:GTP:RHOV effectors [plasma membrane] (Mus musculus)
RHOV effectors [cytosol] (Mus musculus)
PAK1 dimer [cytosol] (Mus musculus)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
x 2
PAK1 [cytosol]
(Mus musculus)
Participates
as a member of
RHOV effectors [cytosol] (Mus musculus)
RHOQ effectors [cytosol] (Mus musculus)
RHOH effectors [cytosol] (Mus musculus)
CDC42 effectors [cytosol] (Mus musculus)
RAC2 plasma membrane effectors [cytosol] (Mus musculus)
RAC1 effectors [cytosol] (Mus musculus)
RHOJ effectors [cytosol] (Mus musculus)
RHOU effectors [cytosol] (Mus musculus)
PAK1,2,3 dimer [cytosol] (Mus musculus)
PAK dimer [cytosol] (Mus musculus)
as a candidate of
RAC3 effectors [cytosol] (Mus musculus)
as an input of
PAK1 binds RAC1:GTP (Mus musculus)
Interaction of PAK1 with Rac1-GTP (Mus musculus)
NF2 binds PAK1 (Mus musculus)
RAC1 and CDC42 activate PAK1 (Mus musculus)
as a component of
PAK1:NF2 [plasma membrane] (Mus musculus)
Inferred From
PAK1 dimer [cytosol]
(Homo sapiens)
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