Epinephrine causes hyperpolarization of pancreatic beta cells in mice by activating (opening) an unidentified potassium channel. In rat pancreatic beta cells this channel appears to be ATP-sensitive, but a knockout of the mouse ATP-sensitive potassium channel does not abolish the effect of epinephrine on potassium conductance.
Rorsman, P, Bokvist, K, Ammälä, C, Arkhammar, P, Berggren, PO, Larsson, O, Wåhlander, K
Sieg, A, Su, J, Muñoz, A, Buchenau, M, Nakazaki, M, Aguilar-Bryan, L, Bryan, J, Ullrich, S
Zhao, Y, Fang, Q, Straub, SG, Sharp, GW
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