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About
What is Reactome ?
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Team
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Our Logo
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Digital Preservation
Contact us
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TAK1 complex [cytosol]
Stable Identifier
R-MMU-446878
Type
Complex
Species
Mus musculus
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Immune System (Mus musculus)
Cytokine Signaling in Immune system (Mus musculus)
Signaling by Interleukins (Mus musculus)
Interleukin-1 family signaling (Mus musculus)
Interleukin-1 signaling (Mus musculus)
Polyubiquitinated TRAF6 binds the TAK1 complex (Mus musculus)
TAK1 complex [cytosol] (Mus musculus)
hp-IRAK1:K6-poly-Ub oligo-TRAF6:TAK1 complex [cytosol] (Mus musculus)
TAK1 complex [cytosol] (Mus musculus)
TAK1 is activated within the TAK1 complex (Mus musculus)
hp-IRAK1:K6-poly-Ub oligo-TRAF6:TAK1 complex [cytosol] (Mus musculus)
TAK1 complex [cytosol] (Mus musculus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Mus musculus)
TAK1 complex [cytosol] (Mus musculus)
TAK1 phosphorylates MKK6 (Mus musculus)
TAK1 complex [cytosol] (Mus musculus)
TAK1-dependent IKK and NF-kappa-B activation (Mus musculus)
Ubiquitination of IKBKG by TRAF6 (Mus musculus)
K63pUb-TRAF6:TAK1 complexes [cytosol] (Mus musculus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Mus musculus)
TAK1 complex [cytosol] (Mus musculus)
Interleukin-17 signaling (Mus musculus)
MAP kinase activation (Mus musculus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Mus musculus)
Activated TAK1 phosphorylates MKK4/MKK7 (Mus musculus)
Activated TAK complexes [cytosol] (Mus musculus)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Mus musculus)
TAK1 complex [cytosol] (Mus musculus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Mus musculus)
TAK1 complex [cytosol] (Mus musculus)
activated TAK1 mediates p38 MAPK activation (Mus musculus)
activated human TAK1 phosphorylates MKK3/MKK6 (Mus musculus)
Activated TAK complexes [cytosol] (Mus musculus)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Mus musculus)
TAK1 complex [cytosol] (Mus musculus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Mus musculus)
TAK1 complex [cytosol] (Mus musculus)
Innate Immune System (Mus musculus)
Alpha-protein kinase 1 signaling pathway (Mus musculus)
ALPK1:ADP-heptose:p-T9-TIFA oligomer:K63pUb-TRAF6 oligomer recruits MAP3K7 (TAK1) (Mus musculus)
TAK1 complex [cytosol] (Mus musculus)
C-type lectin receptors (CLRs) (Mus musculus)
CLEC7A (Dectin-1) signaling (Mus musculus)
K63polyUb-TRAF6 ubiquitinates TAK1 (Mus musculus)
p-T231-CARD9:BCL10:MALT1:K63polyUb-TRAF6 oligomers:TRIKA2 [plasma membrane] (Mus musculus)
TAK1 complex [cytosol] (Mus musculus)
TRIKA2 binds K63polyUb-TRAF6 oligomer (Mus musculus)
TAK1 complex [cytosol] (Mus musculus)
p-T231-CARD9:BCL10:MALT1:K63polyUb-TRAF6 oligomers:TRIKA2 [plasma membrane] (Mus musculus)
TAK1 complex [cytosol] (Mus musculus)
Fc epsilon receptor (FCERI) signaling (Mus musculus)
FCERI mediated NF-kB activation (Mus musculus)
Activation of TAK1 complex bound to pUb-TRAF6 (Mus musculus)
DAG:p-5Y-PKC-theta:CBM oligomer:oligo-K63-poly Ub-TRAF6:TAK1:TAB1:TAB2/3 [plasma membrane] (Mus musculus)
TAK1 complex [cytosol] (Mus musculus)
Phosphorylation of IKK-beta by TAK1 (Mus musculus)
DAG:p-5Y-PKC-theta:CBM oligomer:oligo-K63-poly Ub-TRAF6:TAK1:TAB1:TAB2/3 [plasma membrane] (Mus musculus)
TAK1 complex [cytosol] (Mus musculus)
Recruitment of TAK1 kinase complex to oligo-K63-pUb-TRAF6 (Mus musculus)
DAG:p-5Y-PKC-theta:CBM oligomer:oligo-K63-poly Ub-TRAF6:TAK1:TAB1:TAB2/3 [plasma membrane] (Mus musculus)
TAK1 complex [cytosol] (Mus musculus)
TAK1 complex [cytosol] (Mus musculus)
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways (Mus musculus)
NOD1/2 Signaling Pathway (Mus musculus)
TAK1 is activated (Mus musculus)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Mus musculus)
TAK1 complex [cytosol] (Mus musculus)
TAK1 phosphorylates MKK6 (Mus musculus)
TAK1 complex [cytosol] (Mus musculus)
Toll-like Receptor Cascades (Mus musculus)
Toll Like Receptor 10 (TLR10) Cascade (Mus musculus)
MyD88 cascade initiated on plasma membrane (Mus musculus)
IRAK2 mediated activation of TAK1 complex (Mus musculus)
Activated TRAF6:p-IRAK2 interacts with TAK1 complex (Mus musculus)
TAK1 complex [cytosol] (Mus musculus)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63 pUb:TAK1 complex [plasma membrane] (Mus musculus)
TAK1 complex [cytosol] (Mus musculus)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 (Mus musculus)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63 pUb:TAK1 complex [plasma membrane] (Mus musculus)
TAK1 complex [cytosol] (Mus musculus)
MAP kinase activation (Mus musculus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Mus musculus)
Activated TAK1 phosphorylates MKK4/MKK7 (Mus musculus)
Activated TAK complexes [cytosol] (Mus musculus)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Mus musculus)
TAK1 complex [cytosol] (Mus musculus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Mus musculus)
TAK1 complex [cytosol] (Mus musculus)
activated TAK1 mediates p38 MAPK activation (Mus musculus)
activated human TAK1 phosphorylates MKK3/MKK6 (Mus musculus)
Activated TAK complexes [cytosol] (Mus musculus)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Mus musculus)
TAK1 complex [cytosol] (Mus musculus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Mus musculus)
TAK1 complex [cytosol] (Mus musculus)
TAK1-dependent IKK and NF-kappa-B activation (Mus musculus)
Ubiquitination of IKBKG by TRAF6 (Mus musculus)
K63pUb-TRAF6:TAK1 complexes [cytosol] (Mus musculus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Mus musculus)
TAK1 complex [cytosol] (Mus musculus)
Toll Like Receptor 2 (TLR2) Cascade (Mus musculus)
Toll Like Receptor TLR1:TLR2 Cascade (Mus musculus)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Mus musculus)
IRAK2 mediated activation of TAK1 complex (Mus musculus)
Activated TRAF6:p-IRAK2 interacts with TAK1 complex (Mus musculus)
TAK1 complex [cytosol] (Mus musculus)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63 pUb:TAK1 complex [plasma membrane] (Mus musculus)
TAK1 complex [cytosol] (Mus musculus)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 (Mus musculus)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63 pUb:TAK1 complex [plasma membrane] (Mus musculus)
TAK1 complex [cytosol] (Mus musculus)
MAP kinase activation (Mus musculus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Mus musculus)
Activated TAK1 phosphorylates MKK4/MKK7 (Mus musculus)
Activated TAK complexes [cytosol] (Mus musculus)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Mus musculus)
TAK1 complex [cytosol] (Mus musculus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Mus musculus)
TAK1 complex [cytosol] (Mus musculus)
activated TAK1 mediates p38 MAPK activation (Mus musculus)
activated human TAK1 phosphorylates MKK3/MKK6 (Mus musculus)
Activated TAK complexes [cytosol] (Mus musculus)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Mus musculus)
TAK1 complex [cytosol] (Mus musculus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Mus musculus)
TAK1 complex [cytosol] (Mus musculus)
TAK1-dependent IKK and NF-kappa-B activation (Mus musculus)
Ubiquitination of IKBKG by TRAF6 (Mus musculus)
K63pUb-TRAF6:TAK1 complexes [cytosol] (Mus musculus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Mus musculus)
TAK1 complex [cytosol] (Mus musculus)
Toll Like Receptor TLR6:TLR2 Cascade (Mus musculus)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Mus musculus)
IRAK2 mediated activation of TAK1 complex (Mus musculus)
Activated TRAF6:p-IRAK2 interacts with TAK1 complex (Mus musculus)
TAK1 complex [cytosol] (Mus musculus)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63 pUb:TAK1 complex [plasma membrane] (Mus musculus)
TAK1 complex [cytosol] (Mus musculus)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 (Mus musculus)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63 pUb:TAK1 complex [plasma membrane] (Mus musculus)
TAK1 complex [cytosol] (Mus musculus)
MAP kinase activation (Mus musculus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Mus musculus)
Activated TAK1 phosphorylates MKK4/MKK7 (Mus musculus)
Activated TAK complexes [cytosol] (Mus musculus)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Mus musculus)
TAK1 complex [cytosol] (Mus musculus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Mus musculus)
TAK1 complex [cytosol] (Mus musculus)
activated TAK1 mediates p38 MAPK activation (Mus musculus)
activated human TAK1 phosphorylates MKK3/MKK6 (Mus musculus)
Activated TAK complexes [cytosol] (Mus musculus)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Mus musculus)
TAK1 complex [cytosol] (Mus musculus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Mus musculus)
TAK1 complex [cytosol] (Mus musculus)
TAK1-dependent IKK and NF-kappa-B activation (Mus musculus)
Ubiquitination of IKBKG by TRAF6 (Mus musculus)
K63pUb-TRAF6:TAK1 complexes [cytosol] (Mus musculus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Mus musculus)
TAK1 complex [cytosol] (Mus musculus)
Toll Like Receptor 3 (TLR3) Cascade (Mus musculus)
MAP kinase activation (Mus musculus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Mus musculus)
Activated TAK1 phosphorylates MKK4/MKK7 (Mus musculus)
Activated TAK complexes [cytosol] (Mus musculus)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Mus musculus)
TAK1 complex [cytosol] (Mus musculus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Mus musculus)
TAK1 complex [cytosol] (Mus musculus)
activated TAK1 mediates p38 MAPK activation (Mus musculus)
activated human TAK1 phosphorylates MKK3/MKK6 (Mus musculus)
Activated TAK complexes [cytosol] (Mus musculus)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Mus musculus)
TAK1 complex [cytosol] (Mus musculus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Mus musculus)
TAK1 complex [cytosol] (Mus musculus)
TAK1-dependent IKK and NF-kappa-B activation (Mus musculus)
Ubiquitination of IKBKG by TRAF6 (Mus musculus)
K63pUb-TRAF6:TAK1 complexes [cytosol] (Mus musculus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Mus musculus)
TAK1 complex [cytosol] (Mus musculus)
Toll Like Receptor 4 (TLR4) Cascade (Mus musculus)
MyD88-independent TLR4 cascade (Mus musculus)
TRIF (TICAM1)-mediated TLR4 signaling (Mus musculus)
MAP kinase activation (Mus musculus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Mus musculus)
Activated TAK1 phosphorylates MKK4/MKK7 (Mus musculus)
Activated TAK complexes [cytosol] (Mus musculus)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Mus musculus)
TAK1 complex [cytosol] (Mus musculus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Mus musculus)
TAK1 complex [cytosol] (Mus musculus)
activated TAK1 mediates p38 MAPK activation (Mus musculus)
activated human TAK1 phosphorylates MKK3/MKK6 (Mus musculus)
Activated TAK complexes [cytosol] (Mus musculus)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Mus musculus)
TAK1 complex [cytosol] (Mus musculus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Mus musculus)
TAK1 complex [cytosol] (Mus musculus)
TAK1-dependent IKK and NF-kappa-B activation (Mus musculus)
Ubiquitination of IKBKG by TRAF6 (Mus musculus)
K63pUb-TRAF6:TAK1 complexes [cytosol] (Mus musculus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Mus musculus)
TAK1 complex [cytosol] (Mus musculus)
TRAF6-mediated induction of TAK1 complex within TLR4 complex (Mus musculus)
Activated TLR4:TICAM1:K63pUb-TRAF6 recruits TAK1complex (Mus musculus)
TAK1 complex [cytosol] (Mus musculus)
activated TLR4:TICAM1:K63pUb-TRAF6:free K63pUb:TAK1complex [endosome membrane] (Mus musculus)
TAK1 complex [cytosol] (Mus musculus)
Activation of TAK1 complex bound to activated TLR4 complex (Mus musculus)
activated TLR4:TICAM1:K63pUb-TRAF6:free K63pUb:TAK1complex [endosome membrane] (Mus musculus)
TAK1 complex [cytosol] (Mus musculus)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Mus musculus)
IRAK2 mediated activation of TAK1 complex (Mus musculus)
Activated TRAF6:p-IRAK2 interacts with TAK1 complex (Mus musculus)
TAK1 complex [cytosol] (Mus musculus)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63 pUb:TAK1 complex [plasma membrane] (Mus musculus)
TAK1 complex [cytosol] (Mus musculus)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 (Mus musculus)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63 pUb:TAK1 complex [plasma membrane] (Mus musculus)
TAK1 complex [cytosol] (Mus musculus)
MAP kinase activation (Mus musculus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Mus musculus)
Activated TAK1 phosphorylates MKK4/MKK7 (Mus musculus)
Activated TAK complexes [cytosol] (Mus musculus)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Mus musculus)
TAK1 complex [cytosol] (Mus musculus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Mus musculus)
TAK1 complex [cytosol] (Mus musculus)
activated TAK1 mediates p38 MAPK activation (Mus musculus)
activated human TAK1 phosphorylates MKK3/MKK6 (Mus musculus)
Activated TAK complexes [cytosol] (Mus musculus)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Mus musculus)
TAK1 complex [cytosol] (Mus musculus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Mus musculus)
TAK1 complex [cytosol] (Mus musculus)
TAK1-dependent IKK and NF-kappa-B activation (Mus musculus)
Ubiquitination of IKBKG by TRAF6 (Mus musculus)
K63pUb-TRAF6:TAK1 complexes [cytosol] (Mus musculus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Mus musculus)
TAK1 complex [cytosol] (Mus musculus)
Toll Like Receptor 5 (TLR5) Cascade (Mus musculus)
MyD88 cascade initiated on plasma membrane (Mus musculus)
IRAK2 mediated activation of TAK1 complex (Mus musculus)
Activated TRAF6:p-IRAK2 interacts with TAK1 complex (Mus musculus)
TAK1 complex [cytosol] (Mus musculus)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63 pUb:TAK1 complex [plasma membrane] (Mus musculus)
TAK1 complex [cytosol] (Mus musculus)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 (Mus musculus)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63 pUb:TAK1 complex [plasma membrane] (Mus musculus)
TAK1 complex [cytosol] (Mus musculus)
MAP kinase activation (Mus musculus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Mus musculus)
Activated TAK1 phosphorylates MKK4/MKK7 (Mus musculus)
Activated TAK complexes [cytosol] (Mus musculus)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Mus musculus)
TAK1 complex [cytosol] (Mus musculus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Mus musculus)
TAK1 complex [cytosol] (Mus musculus)
activated TAK1 mediates p38 MAPK activation (Mus musculus)
activated human TAK1 phosphorylates MKK3/MKK6 (Mus musculus)
Activated TAK complexes [cytosol] (Mus musculus)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Mus musculus)
TAK1 complex [cytosol] (Mus musculus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Mus musculus)
TAK1 complex [cytosol] (Mus musculus)
TAK1-dependent IKK and NF-kappa-B activation (Mus musculus)
Ubiquitination of IKBKG by TRAF6 (Mus musculus)
K63pUb-TRAF6:TAK1 complexes [cytosol] (Mus musculus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Mus musculus)
TAK1 complex [cytosol] (Mus musculus)
Toll Like Receptor 7/8 (TLR7/8) Cascade (Mus musculus)
MyD88 dependent cascade initiated on endosome (Mus musculus)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Mus musculus)
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation (Mus musculus)
Activated TRAF6:p-IRAK2 interacts with TAK1 complex upon TLR7/8 or 9 stimulation (Mus musculus)
TAK1 complex [cytosol] (Mus musculus)
MAP kinase activation (Mus musculus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Mus musculus)
Activated TAK1 phosphorylates MKK4/MKK7 (Mus musculus)
Activated TAK complexes [cytosol] (Mus musculus)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Mus musculus)
TAK1 complex [cytosol] (Mus musculus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Mus musculus)
TAK1 complex [cytosol] (Mus musculus)
activated TAK1 mediates p38 MAPK activation (Mus musculus)
activated human TAK1 phosphorylates MKK3/MKK6 (Mus musculus)
Activated TAK complexes [cytosol] (Mus musculus)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Mus musculus)
TAK1 complex [cytosol] (Mus musculus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Mus musculus)
TAK1 complex [cytosol] (Mus musculus)
TAK1-dependent IKK and NF-kappa-B activation (Mus musculus)
Ubiquitination of IKBKG by TRAF6 (Mus musculus)
K63pUb-TRAF6:TAK1 complexes [cytosol] (Mus musculus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Mus musculus)
TAK1 complex [cytosol] (Mus musculus)
Toll Like Receptor 9 (TLR9) Cascade (Mus musculus)
MyD88 dependent cascade initiated on endosome (Mus musculus)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Mus musculus)
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation (Mus musculus)
Activated TRAF6:p-IRAK2 interacts with TAK1 complex upon TLR7/8 or 9 stimulation (Mus musculus)
TAK1 complex [cytosol] (Mus musculus)
MAP kinase activation (Mus musculus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Mus musculus)
Activated TAK1 phosphorylates MKK4/MKK7 (Mus musculus)
Activated TAK complexes [cytosol] (Mus musculus)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Mus musculus)
TAK1 complex [cytosol] (Mus musculus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Mus musculus)
TAK1 complex [cytosol] (Mus musculus)
activated TAK1 mediates p38 MAPK activation (Mus musculus)
activated human TAK1 phosphorylates MKK3/MKK6 (Mus musculus)
Activated TAK complexes [cytosol] (Mus musculus)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Mus musculus)
TAK1 complex [cytosol] (Mus musculus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Mus musculus)
TAK1 complex [cytosol] (Mus musculus)
TAK1-dependent IKK and NF-kappa-B activation (Mus musculus)
Ubiquitination of IKBKG by TRAF6 (Mus musculus)
K63pUb-TRAF6:TAK1 complexes [cytosol] (Mus musculus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Mus musculus)
TAK1 complex [cytosol] (Mus musculus)
Signal Transduction (Mus musculus)
Death Receptor Signaling (Mus musculus)
TNF signaling (Mus musculus)
TNFR1-induced NF-kappa-B signaling pathway (Mus musculus)
TNF:TNFR1:TRADD:TRAF2:K63polyUb-RIPK1:BIRC2/3:LUBAC recruits TAK1 complex (Mus musculus)
TAK1 complex [cytosol] (Mus musculus)
TNF:TNFR1:TRADD:TRAF2:K63polyUb-RIP1:LUBAC:BIRC2/3:TAB1:TAK1:TAB2/3 [plasma membrane] (Mus musculus)
TAK1 complex [cytosol] (Mus musculus)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
MAP3K7 [cytosol]
(Mus musculus)
Tab1 [cytosol]
(Mus musculus)
TAB2,TAB3 [cytosol]
(Mus musculus)
Participates
as an input of
TNF:TNFR1:TRADD:TRAF2:K63polyUb-RIPK1:BIRC2/3:LUBAC recruits TAK1 complex (Mus musculus)
Activated TRAF6:p-IRAK2 interacts with TAK1 complex upon TLR7/8 or 9 stimulation (Mus musculus)
Polyubiquitinated TRAF6 binds the TAK1 complex (Mus musculus)
TRIKA2 binds K63polyUb-TRAF6 oligomer (Mus musculus)
Recruitment of TAK1 kinase complex to oligo-K63-pUb-TRAF6 (Mus musculus)
Activated TLR4:TICAM1:K63pUb-TRAF6 recruits TAK1complex (Mus musculus)
ALPK1:ADP-heptose:p-T9-TIFA oligomer:K63pUb-TRAF6 oligomer recruits MAP3K7 (TAK1) (Mus musculus)
Activated TRAF6:p-IRAK2 interacts with TAK1 complex (Mus musculus)
as a component of
TNF:TNFR1:TRADD:TRAF2:K63polyUb-RIP1:LUBAC:BIRC2/3:TAB1:TAK1:TAB2/3 [plasma membrane] (Mus musculus)
hp-IRAK1:K6-poly-Ub oligo-TRAF6:TAK1 complex [cytosol] (Mus musculus)
p-T231-CARD9:BCL10:MALT1:K63polyUb-TRAF6 oligomers:TRIKA2 [plasma membrane] (Mus musculus)
DAG:p-5Y-PKC-theta:CBM oligomer:oligo-K63-poly Ub-TRAF6:TAK1:TAB1:TAB2/3 [plasma membrane] (Mus musculus)
activated TLR4:TICAM1:K63pUb-TRAF6:free K63pUb:TAK1complex [endosome membrane] (Mus musculus)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63 pUb:TAK1 complex [plasma membrane] (Mus musculus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Mus musculus)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Mus musculus)
Inferred From
TAB1:TAB2,TAB3:TAK1 [cytosol]
(Homo sapiens)
TAK1 complex [cytosol]
(Homo sapiens)
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