Reactome | Ctnnb1 [cytosol]

Ctnnb1 [cytosol]

Stable Identifier

R-MMU-448839

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

cytosol

Synonyms

CTNNB1, Q02248

Locations in the PathwayBrowser for interactor UniProt:P49841

Expand all

External Reference Information

External Reference

UniProt:Q02248 Ctnnb1

Gene Names

Ctnnb1, Catnb

Chain

initiator methionine:1, chain:2-781

Reference Genes

BioGPS Gene:12387 Ctnnb1

ENSEMBL:ENSMUSG00000006932 Ctnnb1

KEGG Gene (Mus musculus):12387 Ctnnb1

Monarch:12387 Ctnnb1

NCBI Gene:12387 Ctnnb1

UCSC:Q02248 Ctnnb1

Reference Transcript

Other Identifiers

10590325

12387

1420811_a_at

1430533_a_at

1450008_a_at

160430_at

17523257

4313560

4400098

4521457

4609610

4627206

4652805

4757991

4761923

4769382

5003908

5142509

5207424

5349730

5405072

5420945

5441155

5513949

5565038

5591510

A_51_P272046

A_52_P424585

GE33471

GO:0003674

GO:0005515

GO:0007155

GO:0008150

GO:0045296

ILMN_2696575

ILMN_2994460

m90364_s_at

mMC007707

Participates

as a member of

alpha/beta catenin [cytosol] (Mus musculus)

as a component of

as an input of

as an output of

Beta-catenin is released from the destruction complex (Mus musculus)

as a candidate of

beta-catenin [cytosol] (Mus musculus)

Other forms of this molecule

phospho-Ctnnb1 [nucleoplasm]

phospho-Ctnnb1 [cytosol]

Ctnnb1 [plasma membrane]

Ctnnb1 [nucleoplasm]

Ctnnb1 [cytosol]

phospho-Ctnnb1 [cytosol]

beta-catenin [cytosol]

phospho-Ctnnb1 [cytosol]

Inferred From

CTNNB1 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_031640.1, NP_001159374.1

Target Pathogen

5b354852be737e166372e9f6

Ensembl

ENSMUSP00000007130, ENSMUSP00000136294, ENSMUST00000007130, ENSMUSG00000006932, ENSMUST00000178812

PRO

Q02248

MGI

88276

PDB

1I7X, 4EV9, 4ONS, 2BCT, 4EVP, 1M1E, 4EVT, 1JPP, 3BCT, 1V18, 4EVA, 3OUW, 1DOW, 4EV8, 3OUX, 1I7W

Interactors (20)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P09803 Cdh1	6	Cdh1 [plasma membrane] (R-MMU-2534244) Epithelial-cadherin precursor [plasma membrane] (R-MMU-199081) Cdh1 [extracellular region] (R-MMU-2534158) Cdh1 [plasma membrane] (R-MMU-202940) Cdh1 [plasma membrane] (R-MMU-202929) Cdh1 [plasma membrane] (R-MMU-198003)	0.858	16
UniProt:O35625 Axin1	8	Axin1 [cytosol] (R-MMU-4641133) Phospho Axin1 [cytosol] (R-MMU-206175) phospho-Axin1 [cytosol] (R-MMU-3640864) phospho-Axin1 [cytosol] (R-MMU-3640841) Axin1 [cytosol] (R-MMU-205727) Phospho (3 sites) Axin1 [cytosol] (R-MMU-205737) phospho-Axin1 [cytosol] (R-MMU-206040) Axin1 [cytosol] (R-MMU-195249)	0.725	9
UniProt:P35438 Grin1	3	Grin1 [endoplasmic reticulum membrane] (R-MMU-9610359) Grin1 [plasma membrane] (R-MMU-3928395) Grin1 [transport vesicle membrane] (R-MMU-9610566)	0.643	4
UniProt:P25054 APC	86	APC C1410* [cytosol] (R-HSA-9666925) APC R213* [cytosol] (R-HSA-9666924) APC K1310* [cytosol] (R-HSA-9666926) APC R499* [cytosol] (R-HSA-9666927) APC R1450* [cytosol] (R-HSA-5251499) APC G1357* [cytosol] (R-HSA-9666940) APC L1488* [cytosol] (R-HSA-9666941) APC S1400* [cytosol] (R-HSA-9666942) APC S1346* [cytosol] (R-HSA-9666943) APC R405* [cytosol] (R-HSA-9666936) APC S1281* [cytosol] (R-HSA-9666937) APC E1573* [cytosol] (R-HSA-9666938) APC R805* [cytosol] (R-HSA-9666939) APC R1386* [cytosol] (R-HSA-9666932) APC S1327* [cytosol] (R-HSA-9666933) APC E1209* [cytosol] (R-HSA-9666934) APC Q1469* [cytosol] (R-HSA-9666935) APC R564* [cytosol] (R-HSA-9666928) APC E1536* [cytosol] (R-HSA-9666929) APC G1288* [cytosol] (R-HSA-9666930) APC G1312* [cytosol] (R-HSA-9666931) APC R283* [cytosol] (R-HSA-9666988) APC Q1367* [cytosol] (R-HSA-9666989) APC E1353* [cytosol] (R-HSA-9666990) APC R332* [cytosol] (R-HSA-9666991) APC K993* [cytosol] (R-HSA-9666984) APC R876* [cytosol] (R-HSA-9666985) APC R302* [cytosol] (R-HSA-9666986) APC E1309* [cytosol] (R-HSA-9666987) APC Y935* [cytosol] (R-HSA-9666980) APC E1286* [cytosol] (R-HSA-9666981) APC Q1378* [cytosol] (R-HSA-9666982) APC R554* [cytosol] (R-HSA-9666983) APC S1356* [cytosol] (R-HSA-9666976) APC R232* [cytosol] (R-HSA-9666977) APC E1379* [cytosol] (R-HSA-9666978) APC E984* [cytosol] (R-HSA-9666979) APC R1114* [cytosol] (R-HSA-9666996) APC S1282* [cytosol] (R-HSA-9666997) APC Q1328* [cytosol] (R-HSA-9666998) APC E1295* [cytosol] (R-HSA-9666992) APC E1151* [cytosol] (R-HSA-9666993) APC E1322* [cytosol] (R-HSA-9666994) APC E1345* [cytosol] (R-HSA-9666995) APC K1308* [cytosol] (R-HSA-9666956) APC S1344* [cytosol] (R-HSA-9666957) APC E1577* [cytosol] (R-HSA-9666958) APC Q1127* [cytosol] (R-HSA-9666959) APC E1464* [cytosol] (R-HSA-9666952) APC E1317* [cytosol] (R-HSA-9666953) APC G1309Dfs4 [cytosol] (R-HSA-4791251) APC W1049 [cytosol] (R-HSA-9666954) APC Q1429* [cytosol] (R-HSA-9666955) APC L1564* [cytosol] (R-HSA-9666948) APC Q1294* [cytosol] (R-HSA-9666949) APC K1363* [cytosol] (R-HSA-9666950) APC E1408* [cytosol] (R-HSA-9666951) APC E1284* [cytosol] (R-HSA-9666944) APC E1374* [cytosol] (R-HSA-9666945) APC Q767* [cytosol] (R-HSA-9666946) APC E941* [cytosol] (R-HSA-9666947) APC Q1303* [cytosol] (R-HSA-9666972) APC S943* [cytosol] (R-HSA-9666973) APC E1306* [cytosol] (R-HSA-9666975) APC S895* [cytosol] (R-HSA-9666969) APC S1315* [cytosol] (R-HSA-9666970) APC G1412* [cytosol] (R-HSA-9666971) APC Y1376* [cytosol] (R-HSA-9666964) APC Q886* [cytosol] (R-HSA-9666965) APC S1392* [cytosol] (R-HSA-9666966) APC S1539* [cytosol] (R-HSA-9666967) APC E1451* [cytosol] (R-HSA-9666960) APC E1397* [cytosol] (R-HSA-9666961) APC Q1406* [cytosol] (R-HSA-9666962) APC E1544* [cytosol] (R-HSA-9666963) APC F1197* [cytosol] (R-HSA-5246655) APC Q1338* [cytosol] (R-HSA-5246654) APC S811* [cytosol] (R-HSA-5246652) APC I1417 fs2 [cytosol] (R-HSA-5246651) APC E1554 [cytosol] (R-HSA-5246648) p-ub-APC [cytosol] (R-HSA-3009421) K63polyUb-APC [cytosol] (R-HSA-5246690) APC [nucleoplasm] (R-HSA-3361755) APC(1-777) [cytosol] (R-HSA-2976014) APC(778-2843) [cytosol] (R-HSA-2976013) APC [cytosol] (R-HSA-2976015)	0.623	8
UniProt:P49841 GSK3B	4	p-S9-GSK3B [cytosol] (R-HSA-3149577) GSK3B del304-316 [cytosol] (R-HSA-5339682) GSK3B [cytosol] (R-HSA-2997551) GSK3B [nucleoplasm] (R-HSA-2022823)	0.623	3
UniProt:Q9NSA3 CTNNBIP1	1	CTNNBIP1 [nucleoplasm] (R-HSA-3772388)	0.623	7
UniProt:Q9DBG9	1	Tax1bp3 [cytosol] (R-MMU-5666217)	0.611	6
UniProt:P26231 Ctnna1	3	Ctnna1 [cytosol] (R-MMU-191697) unfolded KIF13A [cytosol] (R-MMU-391268) Ctnna1 [plasma membrane] (R-MMU-191735)	0.609	2
UniProt:Q9JJN6	1	Ctnnbip1 [nucleoplasm] (R-MMU-3772388)	0.593	5
UniProt:P45481 Crebbp	4	Crebbp [nucleoplasm] (R-MMU-556795) Crebbp [nucleoplasm] (R-MMU-193545) Foxo4-S-S-Crebbp [nucleoplasm] (R-MMU-9617719) Sumo1-K999,K1034,K1057-Crebbp [nucleoplasm] (R-MMU-3927936)	0.589	3
UniProt:Q924A0	2	Tcf7l2 [nucleoplasm] (R-MMU-201923) phospho-Tcf7l2 [nucleoplasm] (R-MMU-4411392)	0.564	5
UniProt:O15047 SETD1A	1	SETD1A [nucleoplasm] (R-HSA-3239027)	0.544	2
UniProt:P83510	1	Tnik [cytosol] (R-MMU-3214889)	0.527	3
UniProt:P33148 CADHF			0.525	4
UniProt:P97458 PROP1			0.524	2
UniProt:F1MSG6 RPGF2			0.499	2
UniProt:Q04207	6	Rela [cytosol] (R-MMU-168172) Rela [nucleoplasm] (R-MMU-177676) phospho-Rela [nucleoplasm] (R-MMU-5624468) phospho-Rela [nucleoplasm] (R-MMU-5660642) Rela [nucleoplasm] (R-MMU-8865233) Rela [nucleoplasm] (R-MMU-4755466)	0.499	5
UniProt:O54826 AF10			0.499	2
UniProt:P28828 PTPRM			0.499	2
UniProt:P35569 Irs1	8	phospho-Irs1 [plasma membrane] (R-MMU-2445090) p-Irs1 [cytosol] (R-MMU-2671869) Irs1 [plasma membrane] (R-MMU-2425392) Phospho-IRS1 (by NTRK1) [cytosol] (R-MMU-198285) Irs1 [cytosol] (R-MMU-198257) Irs1 [cytosol] (R-MMU-74769) phospho-Irs1 [cytosol] (R-MMU-74772) phospho-Irs1 [plasma membrane] (R-MMU-198366)	0.462	2

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