Phosphorylation of Khsrp by p38

Stable Identifier
R-MMU-451204
Type
Reaction [transition]
Species
Mus musculus
Compartment
General
SVG |   | PPTX  | SBGN
Phosphorylation of Khsrp by p38

Activated p38 alpha and beta phoshorylate Khsrp at threonine692. The phosphorylation interferes with the ability of Khsrp to bind RNA.

Literature References
PubMed ID Title Journal Year
16364914 p38-dependent phosphorylation of the mRNA decay-promoting factor KSRP controls the stability of select myogenic transcripts

Briata, P, Forcales, SV, Ponassi, M, Corte, G, Chen, CY, Karin, M, Puri, PL, Gherzi, R

Mol Cell 2005
Participants
Catalyst Activity
Catalyst Activity
Title
protein serine/threonine kinase activity of phospho-MAPK p38 alpha/beta [cytosol]
Physical Entity
Activity
Orthologous Events
Authored
Reviewed
Created