Kat2b (Pcaf) acetylates Taf1b in SL1 Complex

Stable Identifier
R-MMU-5211235
Type
Reaction
Species
Mus musculus
Compartment
Summation

Kat2b (Pcaf) and to a lesser extent Kat2a (Gcn5) acetylate the Taf1b (Taf(1)68) subunit of the SL1 complex. Acetylation of Taf1b is required for transcription of rRNA genes.

Literature References
PubMed ID Title Journal Year
11250901 Acetylation of TAF(I)68, a subunit of TIF-IB/SL1, activates RNA polymerase I transcription.

Muth, V, Nadaud, S, Grummt, I, Voit, R

EMBO J 2001
Participants
Catalyst Activity
Catalyst Activity
Title
acetyltransferase activity of Kat2b [nucleoplasm]
Physical Entity
Activity
Orthologous Events
Authored
Reviewed