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Mouse Vegfr2-Human CSF1R fusion protein [plasma membrane]
Stable Identifier
R-MMU-5218738
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
plasma membrane
Synonyms
Kdr, Vascular endothelial growth factor receptor 2
Literature References
PubMed ID
Title
Journal
Year
11278468
Identification of tyrosine residues in vascular endothelial growth factor receptor-2/FLK-1 involved in activation of phosphatidylinositol 3-kinase and cell proliferation
Rahimi, N
,
Lashkari, K
,
Dayanir, V
,
Meyer, RD
J. Biol. Chem.
2001
External Reference Information
External Reference
UniProt:P35918 Kdr
Gene Names
Kdr, Flk-1, Flk1
Chain
signal peptide:1-19, chain:20-1345
Reference Genes
BioGPS Gene:16542 Kdr
KEGG:mmu:16542 Kdr
Monarch:16542 Kdr
NCBI Gene:16542 Kdr
UCSC:P35918 Kdr
Reference Transcript
RefSeq:NM_010612.2 Kdr
Other Identifiers
104265_at
10530692
1449379_at
16542
17448924
4338003
4352412
4395666
4418219
4427451
4442207
4468225
4473769
4583696
4600609
4622271
4626020
4691299
4702680
4703206
4727771
4730206
4763191
4784893
4805198
4848103
4931359
5006063
5105433
5147666
5208733
5251220
5253488
5305488
5372814
5379577
5380309
5483327
5564315
5585044
5606662
A_51_P316553
A_52_P478193
A_55_P2094469
GE35648
GO:0001525
GO:0001541
GO:0001569
GO:0001570
GO:0001666
GO:0001934
GO:0001936
GO:0001938
GO:0001945
GO:0002042
GO:0002053
GO:0002070
GO:0003013
GO:0003085
GO:0003157
GO:0003158
GO:0003416
GO:0003824
GO:0004672
GO:0004713
GO:0004714
GO:0005021
GO:0005178
GO:0005515
GO:0005524
GO:0005576
GO:0005634
GO:0005737
GO:0005768
GO:0005769
GO:0005783
GO:0005794
GO:0005886
GO:0006468
GO:0007169
GO:0007204
GO:0008284
GO:0008360
GO:0008584
GO:0009410
GO:0009897
GO:0009986
GO:0010463
GO:0010595
GO:0010629
GO:0015026
GO:0016020
GO:0016239
GO:0016477
GO:0016740
GO:0018108
GO:0019838
GO:0022414
GO:0030054
GO:0030097
GO:0030154
GO:0030324
GO:0030335
GO:0030513
GO:0030949
GO:0031410
GO:0032008
GO:0035162
GO:0035924
GO:0036324
GO:0038083
GO:0038084
GO:0038085
GO:0042311
GO:0042802
GO:0043025
GO:0043129
GO:0043226
GO:0043235
GO:0043408
GO:0043410
GO:0043524
GO:0043536
GO:0045121
GO:0045165
GO:0045296
GO:0045446
GO:0045766
GO:0046777
GO:0048010
GO:0048170
GO:0048286
GO:0048597
GO:0048754
GO:0048812
GO:0048856
GO:0048870
GO:0050673
GO:0050679
GO:0050850
GO:0050927
GO:0051770
GO:0051894
GO:0051897
GO:0051901
GO:0055074
GO:0060089
GO:0060837
GO:0061042
GO:0061154
GO:0070161
GO:0070374
GO:0071526
GO:0071944
GO:0072089
GO:0090050
GO:0090141
GO:0097443
GO:0140096
GO:1901532
GO:1903010
GO:1904881
GO:2000352
GO:2000648
GO:2001028
GO:2001214
ILMN_1257223
ILMN_2572649
ILMN_2665788
mMC003369
x59397_s_at
Participates
as a component of
Mouse Vegfr2-Human CSF1R fusion protein:p85-Pi3k [plasma membrane] (Mus musculus)
as an input of
P85-subuunit of PI3K binds p-6Y-VEGFR2 (Mus musculus)
Other forms of this molecule
p-Y799,Y1052,Y1172-Kdr [plasma membrane]
Kdr [plasma membrane]
VEGFR2 [plasma membrane]
phospho-p-6Y-VEGFR2 [plasma membrane]
Modified Residues
Name
Insertion of residues 20 to 517 at 733 from UniProt:P07333 CSF1R
Coordinate
733
Cross References
RefSeq
NP_034742.2
ZINC - Investigational
VGFR2_MOUSE
ZINC - World Drugs
VGFR2_MOUSE
ENSEMBL
ENSMUSP00000109144
,
ENSMUST00000113516
ZINC - FDA approved
VGFR2_MOUSE
ZINC - Substances
VGFR2_MOUSE
ZINC target
P35918
PRO
P35918
MGI
96683
ZINC - Predictions - Purchasable
VGFR2_MOUSE
Interactors (5)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P35917 Flt4
2
p-Y1063,Y1230-Flt4 [plasma membrane]
(R-MMU-9860573)
Flt4 [plasma membrane]
(R-MMU-9860490)
0.564
3
UniProt:P08581 MET
7
p-Y1234,Y1235,Y1349,Y1356-MET [plasma membrane]
(R-HSA-6806973)
MET [plasma membrane]
(R-HSA-419603)
p-Y1003,4Y-MET [plasma membrane]
(R-HSA-8874689)
p-Y1234,Y1235,Y1356-MET [plasma membrane]
(R-HSA-6807014)
MonoUb-K,p-Y1003,4Y-MET [plasma membrane]
(R-HSA-8875180)
MonoUb-K,p-Y1234,Y1235,Y1349,Y1356-MET [plasma membrane]
(R-HSA-8875181)
p-Y1349,Y1356-MET [plasma membrane]
(R-HSA-6807032)
0.563
3
UniProt:P16056
7
phospho-p-Y1349,Y1356-MET [plasma membrane]
(R-MMU-6807032)
phospho-MonoUb-K,p-Y1234,Y1235,Y1349,Y1356-MET [plasma membrane]
(R-MMU-8875181)
phospho-MonoUb-K,p-Y1003,4Y-MET [plasma membrane]
(R-MMU-8875180)
phospho-p-Y1234,Y1235,Y1356-MET [plasma membrane]
(R-MMU-6807014)
phospho-p-Y1003,4Y-MET [plasma membrane]
(R-MMU-8874689)
MET [plasma membrane]
(R-MMU-419603)
phospho-p-Y1234,Y1235,Y1349,Y1356-MET [plasma membrane]
(R-MMU-6806973)
0.563
3
UniProt:P09619 PDGFRB
3
p-12Y-PDGFRB [plasma membrane]
(R-HSA-186803)
PDGFRB [plasma membrane]
(R-HSA-186767)
p-11Y-PDGFRB [plasma membrane]
(R-HSA-8864039)
0.524
4
UniProt:Q62077 Plcg1
10
p-Y-Plcg1 [cytosol]
(R-MMU-9029083)
Plcg1 [cytosol]
(R-MMU-9638030)
p-4Y-Plcg1 [plasma membrane]
(R-MMU-9030452)
phospho-p-Y771,Y783-PLCG1 [plasma membrane]
(R-MMU-1169084)
phospho-p-Y771,Y783,Y1254-PLCG1 [cytosol]
(R-MMU-202357)
PLCG1 [plasma membrane]
(R-MMU-167682)
P-Plcg1 [cytosol]
(R-MMU-1251936)
Plcg1 [plasma membrane]
(R-MMU-1251925)
PLCG1 [cytosol]
(R-MMU-202320)
phospho-p-4Y-PLCG1 [plasma membrane]
(R-MMU-167679)
0.462
2
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