Expression of Period-1 (Per1)

Stable Identifier
R-MMU-549491
Type
Reaction [omitted]
Species
Mus musculus
Compartment
General
SVG |   | PPTX  | SBGN
Expression of Period-1 (Per1)

The Period-1 (Per1) gene is transcribed to yield mRNA and the mRNA is translated to yield protein. An E-box element in the promoter of Per1 binds the Bmal1:Clock (Arntl:Clock) heterodimer and confers circadian expression on Per1

Literature References
PubMed ID Title Journal Year
10857746 The human and mouse Period1 genes: five well-conserved E-boxes additively contribute to the enhancement of mPer1 transcription

Hida, A, Koike, N, Hirose, M, Hattori, M, Sakaki, Y, Tei, H

Genomics 2000
9323128 RIGUI, a putative mammalian ortholog of the Drosophila period gene

Sun, ZS, Albrecht, U, Zhuchenko, O, Bailey, J, Eichele, G, Lee, CC

Cell 1997
18815372 Analysis and synthesis of high-amplitude Cis-elements in the mammalian circadian clock

Kumaki, Y, Ukai-Tadenuma, M, Uno, KD, Nishio, J, Masumoto, KH, Nagano, M, Komori, T, Shigeyoshi, Y, Hogenesch, JB, Ueda, HR

Proc Natl Acad Sci U S A 2008
9427249 Two period homologs: circadian expression and photic regulation in the suprachiasmatic nuclei

Shearman, LP, Zylka, MJ, Weaver, DR, Kolakowski LF, Jr, Reppert, SM

Neuron 1997
19330005 CK2alpha phosphorylates BMAL1 to regulate the mammalian clock

Tamaru, T, Hirayama, J, Isojima, Y, Nagai, K, Norioka, S, Takamatsu, K, Sassone-Corsi, P

Nat Struct Mol Biol 2009
9619629 A new mammalian period gene predominantly expressed in the suprachiasmatic nucleus

Takumi, T, Matsubara, C, Shigeyoshi, Y, Taguchi, K, Yagita, K, Maebayashi, Y, Sakakida, Y, Okumura, K, Takashima, N, Okamura, H

Genes Cells 1998
16507766 Dual role of the CLOCK/BMAL1 circadian complex in transcriptional regulation

Kondratov, RV, Shamanna, RK, Kondratova, AA, Gorbacheva, VY, Antoch, MP

FASEB J 2006
12865428 Genome-wide expression analysis of mouse liver reveals CLOCK-regulated circadian output genes

Oishi, K, Miyazaki, K, Kadota, K, Kikuno, R, Nagase, T, Atsumi, G, Ohkura, N, Azama, T, Mesaki, M, Yukimasa, S, Kobayashi, H, Iitaka, C, Umehara, T, Horikoshi, M, Kudo, T, Shimizu, Y, Yano, M, Monden, M, Machida, K, Matsuda, J, Horie, S, Todo, T, Ishida, N

J Biol Chem 2003
9428527 A differential response of two putative mammalian circadian regulators, mper1 and mper2, to light

Albrecht, U, Sun, ZS, Eichele, G, Lee, CC

Cell 1997
17115977 Cryptochromes impair phosphorylation of transcriptional activators in the clock: a general mechanism for circadian repression

Dardente, H, Fortier, EE, Martineau, V, Cermakian, N

Biochem J 2007
12483227 Rhythmic histone acetylation underlies transcription in the mammalian circadian clock

Etchegaray, JP, Lee, C, Wade, PA, Reppert, SM

Nature 2003
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