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phospho-Plcg2 [plasma membrane]
Stable Identifier
R-MMU-5607640
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
plasma membrane
Synonyms
p-Y753,Y759-PLCG2, Q8CIH5
Locations in the PathwayBrowser
Expand all
Immune System (Mus musculus)
Innate Immune System (Mus musculus)
C-type lectin receptors (CLRs) (Mus musculus)
CLEC7A (Dectin-1) signaling (Mus musculus)
p-Y753,Y759-PLCG2 hydrolyses PIP2 (Mus musculus)
phospho-Plcg2 [plasma membrane] (Mus musculus)
p-Y753,Y759-PLCG2 translocates from cytosol to plasma membrane (Mus musculus)
phospho-Plcg2 [plasma membrane] (Mus musculus)
Dectin-2 family (Mus musculus)
PLCG2 translocates from cytosol to plasma membrane (Mus musculus)
phospho-Plcg2 [plasma membrane] (Mus musculus)
External Reference Information
External Reference
UniProt:Q8CIH5 Plcg2
Gene Names
Plcg2
Chain
chain:1-1265
Reference Genes
BioGPS Gene:234779 Plcg2
ENSEMBL:ENSMUSG00000034330 Plcg2
KEGG Gene (Mus musculus):234779 Plcg2
Monarch:234779 Plcg2
NCBI Gene:234779 Plcg2
UCSC:Q8CIH5 Plcg2
Reference Transcript
RefSeq:NM_172285.2 Plcg2
Other Identifiers
103503_at
10575799
1426926_at
17505995
234779
4316765
4328643
4347247
4418921
4464023
4513213
4544728
4546585
4561863
4688301
4698350
4706243
4722083
4757740
4778254
4794214
4839532
4844036
4845341
4893048
4914276
4922360
4930594
4951069
5054246
5125785
5150133
5172364
5188123
5197415
5235706
5254217
5381157
5396840
5400208
5436845
5465325
5476990
5598465
GE113622
GO:0003674
GO:0004435
GO:0005515
GO:0006629
GO:0007165
GO:0008081
GO:0008150
GO:0009056
GO:0009395
GO:0035556
ILMN_2601833
c76245_rc_at
mMC012791
Participates
as an output of
p-Y753,Y759-PLCG2 translocates from cytosol to plasma membrane (Mus musculus)
PLCG2 translocates from cytosol to plasma membrane (Mus musculus)
Other forms of this molecule
p-Y-Plcg2 [cytosol]
Plcg2 [cytosol]
phospho-Plcg2 [cytosol]
phospho-Plcg2 [plasma membrane]
p-Y753,Y759-Plcg2 [cytosol]
phospho-Plcg2 [plasma membrane]
Plcg2 [plasma membrane]
phospho-Plcg2 [plasma membrane]
Inferred From
p-Y753,Y759-PLCG2 [plasma membrane]
(Homo sapiens)
Modified Residues
Name
O4'-phospho-L-tyrosine at 753 (in Homo sapiens)
Coordinate
753
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 759 (in Homo sapiens)
Coordinate
759
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Cross References
RefSeq
NP_758489.1
IntEnz
3.1.4.11
Ensembl
ENSMUSP00000079991
,
ENSMUSG00000034330
,
ENSMUST00000081232
PRO
Q8CIH5
MGI
97616
PDB
2DX0
,
2EQI
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P14753 Epor
3
p-8Y-Epor [plasma membrane]
(R-MMU-9006275)
EpoR [plasma membrane]
(R-MMU-206154)
phospho-Epor [plasma membrane]
(R-MMU-9006274)
0.524
2
UniProt:P25911 Lyn
7
Lyn [endocytic vesicle membrane]
(R-MMU-9705728)
Lyn [lysosomal membrane]
(R-MMU-9707903)
Lyn [plasma membrane]
(R-MMU-197943)
phospho-Lyn [cytosol]
(R-MMU-8942608)
Lyn [plasma membrane]
(R-MMU-9606875)
phospho-Lyn [plasma membrane]
(R-MMU-2454229)
Lyn [cytosol]
(R-MMU-1112642)
0.524
2
UniProt:P07333 CSF1R
1
CSF1R [plasma membrane]
(R-HSA-197667)
0.482
2
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