Reactome | TUBB2A [axonemal microtubule]

TUBB2A [axonemal microtubule]

Stable Identifier

R-MMU-5610431

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

axonemal microtubule

Synonyms

Q7TMM9

Locations in the PathwayBrowser

Expand all

Organelle biogenesis and maintenance (Mus musculus)

- Cilium Assembly (Mus musculus)
  - Intraflagellar transport (Mus musculus)
    - Anterograde IFT (Mus musculus)
      - anterograde IFT trains [ciliary tip] (Mus musculus)
        
        active kinesin-2 motors [ciliary tip] (Mus musculus)
        
        acetylated microtubule [axonemal microtubule] (Mus musculus)
        
        Ac K40 alpha tubulin-beta tubulin dimer [axonemal microtubule] (Mus musculus)
        
        beta tubulin:GDP [axonemal microtubule] (Mus musculus)
        
        beta tubulin [axonemal microtubule] (Mus musculus)
        
        TUBB2A [axonemal microtubule] (Mus musculus)
      - anterograde IFT trains [cilium] (Mus musculus)
        
        active kinesin-2 motors [cilium] (Mus musculus)
        
        acetylated microtubule [axonemal microtubule] (Mus musculus)
        
        Ac K40 alpha tubulin-beta tubulin dimer [axonemal microtubule] (Mus musculus)
        
        beta tubulin:GDP [axonemal microtubule] (Mus musculus)
        
        beta tubulin [axonemal microtubule] (Mus musculus)
        
        TUBB2A [axonemal microtubule] (Mus musculus)
    - Assembly of the anterograde IFT train (Mus musculus)
      - active kinesin-2 motors [cilium] (Mus musculus)
        
        acetylated microtubule [axonemal microtubule] (Mus musculus)
        
        Ac K40 alpha tubulin-beta tubulin dimer [axonemal microtubule] (Mus musculus)
        
        beta tubulin:GDP [axonemal microtubule] (Mus musculus)
        
        beta tubulin [axonemal microtubule] (Mus musculus)
        
        TUBB2A [axonemal microtubule] (Mus musculus)
      - anterograde IFT trains [cilium] (Mus musculus)
        
        active kinesin-2 motors [cilium] (Mus musculus)
        
        acetylated microtubule [axonemal microtubule] (Mus musculus)
        
        Ac K40 alpha tubulin-beta tubulin dimer [axonemal microtubule] (Mus musculus)
        
        beta tubulin:GDP [axonemal microtubule] (Mus musculus)
        
        beta tubulin [axonemal microtubule] (Mus musculus)
        
        TUBB2A [axonemal microtubule] (Mus musculus)
    - Assembly of the retrograde IFT train (Mus musculus)
      - active dynein-2 motors [ciliary tip] (Mus musculus)
        
        acetylated microtubule [axonemal microtubule] (Mus musculus)
        
        Ac K40 alpha tubulin-beta tubulin dimer [axonemal microtubule] (Mus musculus)
        
        beta tubulin:GDP [axonemal microtubule] (Mus musculus)
        
        beta tubulin [axonemal microtubule] (Mus musculus)
        
        TUBB2A [axonemal microtubule] (Mus musculus)
      - retrograde IFT trains [ciliary tip] (Mus musculus)
        
        active dynein-2 motors [ciliary tip] (Mus musculus)
        
        acetylated microtubule [axonemal microtubule] (Mus musculus)
        
        Ac K40 alpha tubulin-beta tubulin dimer [axonemal microtubule] (Mus musculus)
        
        beta tubulin:GDP [axonemal microtubule] (Mus musculus)
        
        beta tubulin [axonemal microtubule] (Mus musculus)
        
        TUBB2A [axonemal microtubule] (Mus musculus)
    - Retrograde IFT (Mus musculus)
      - retrograde IFT trains [ciliary tip] (Mus musculus)
        
        active dynein-2 motors [ciliary tip] (Mus musculus)
        
        acetylated microtubule [axonemal microtubule] (Mus musculus)
        
        Ac K40 alpha tubulin-beta tubulin dimer [axonemal microtubule] (Mus musculus)
        
        beta tubulin:GDP [axonemal microtubule] (Mus musculus)
        
        beta tubulin [axonemal microtubule] (Mus musculus)
        
        TUBB2A [axonemal microtubule] (Mus musculus)
      - retrograde IFT trains [cilium] (Mus musculus)
        
        active dynein-2 motors [cilium] (Mus musculus)
        
        acetylated microtubule [axonemal microtubule] (Mus musculus)
        
        Ac K40 alpha tubulin-beta tubulin dimer [axonemal microtubule] (Mus musculus)
        
        beta tubulin:GDP [axonemal microtubule] (Mus musculus)
        
        beta tubulin [axonemal microtubule] (Mus musculus)
        
        TUBB2A [axonemal microtubule] (Mus musculus)
    - The anterograde IFT train dissociates (Mus musculus)
      - acetylated microtubule [axonemal microtubule] (Mus musculus)
        
        Ac K40 alpha tubulin-beta tubulin dimer [axonemal microtubule] (Mus musculus)
        
        beta tubulin:GDP [axonemal microtubule] (Mus musculus)
        
        beta tubulin [axonemal microtubule] (Mus musculus)
        
        TUBB2A [axonemal microtubule] (Mus musculus)
      - anterograde IFT trains [ciliary tip] (Mus musculus)
        
        active kinesin-2 motors [ciliary tip] (Mus musculus)
        
        acetylated microtubule [axonemal microtubule] (Mus musculus)
        
        Ac K40 alpha tubulin-beta tubulin dimer [axonemal microtubule] (Mus musculus)
        
        beta tubulin:GDP [axonemal microtubule] (Mus musculus)
        
        beta tubulin [axonemal microtubule] (Mus musculus)
        
        TUBB2A [axonemal microtubule] (Mus musculus)
    - The retrograde IFT train dissociates (Mus musculus)
      - acetylated microtubule [axonemal microtubule] (Mus musculus)
        
        Ac K40 alpha tubulin-beta tubulin dimer [axonemal microtubule] (Mus musculus)
        
        beta tubulin:GDP [axonemal microtubule] (Mus musculus)
        
        beta tubulin [axonemal microtubule] (Mus musculus)
        
        TUBB2A [axonemal microtubule] (Mus musculus)
      - retrograde IFT trains [cilium] (Mus musculus)
        
        active dynein-2 motors [cilium] (Mus musculus)
        
        acetylated microtubule [axonemal microtubule] (Mus musculus)
        
        Ac K40 alpha tubulin-beta tubulin dimer [axonemal microtubule] (Mus musculus)
        
        beta tubulin:GDP [axonemal microtubule] (Mus musculus)
        
        beta tubulin [axonemal microtubule] (Mus musculus)
        
        TUBB2A [axonemal microtubule] (Mus musculus)

External Reference Information

External Reference

UniProt:Q7TMM9 Tubb2a

Gene Names

Tubb2a, Tubb2

Chain

chain:1-445

Reference Genes

BioGPS Gene:22151 Tubb2a

ENSEMBL:ENSMUSG00000058672 Tubb2a

KEGG Gene (Mus musculus):22151 Tubb2a

Monarch:22151 Tubb2a

NCBI Gene:22151 Tubb2a

UCSC:Q7TMM9 Tubb2a

Reference Transcript

RefSeq:NM_009450.2 Tubb2a

Other Identifiers

10408610

1427347_s_at

17291767

22151

4372763

4418350

4472628

4480755

4576349

4589620

4785204

4916115

5358162

5361640

5425407

5444944

5460225

5583546

94835_f_at

A_51_P103659

A_52_P621603

GE39504

GO:0000166

GO:0000226

GO:0000278

GO:0003824

GO:0003924

GO:0005198

GO:0005200

GO:0005525

GO:0005576

GO:0005737

GO:0005856

GO:0005874

GO:0007010

GO:0007017

GO:0015630

GO:0016787

GO:0021987

GO:0043226

GO:0045171

GO:0046872

GO:0048856

GO:0072686

ILMN_2485044

ILMN_2588051

Msa.11746.0_f_at

Msa.5864.0_f_at

mMC014073

Participates

as a candidate of

beta tubulin [axonemal microtubule] (Mus musculus)

Other forms of this molecule

Polyglycyl-TUBB2A [cytosol]

Polyglutamyl-TUBB2A [cytosol]

Tubulin beta-2A chain [cytosol]

Inferred From

TUBB2A [axonemal microtubule] (Homo sapiens)

Cross References

RefSeq

NP_033476.1

Ensembl

ENSMUSG00000058672, ENSMUST00000056427, ENSMUSP00000060246

PRO

Q7TMM9

MGI

107861

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