Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
Tiam2 [cytosol]
Stable Identifier
R-MMU-561165
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
cytosol
Synonyms
TIAM2, Q6ZPF3
Locations in the PathwayBrowser
Expand all
Signal Transduction (Mus musculus)
Death Receptor Signaling (Mus musculus)
p75 NTR receptor-mediated signalling (Mus musculus)
Cell death signalling via NRAGE, NRIF and NADE (Mus musculus)
NRAGE signals death through JNK (Mus musculus)
p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor (Mus musculus)
GEFs [cytosol] (Mus musculus)
Tiam2 [cytosol] (Mus musculus)
Signaling by GPCR (Mus musculus)
GPCR downstream signalling (Mus musculus)
G alpha (12/13) signalling events (Mus musculus)
GEFs activate RhoA,B,C (Mus musculus)
GEFs [cytosol] (Mus musculus)
Tiam2 [cytosol] (Mus musculus)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Mus musculus)
Signaling by Rho GTPases (Mus musculus)
RHO GTPase cycle (Mus musculus)
RAC1 GTPase cycle (Mus musculus)
RAC1 GEFs activate RAC1 (Mus musculus)
RAC1 GEFs [cytosol] (Mus musculus)
Tiam2 [cytosol] (Mus musculus)
External Reference Information
External Reference
UniProt:Q6ZPF3
Gene Names
Tiam2
Reference Genes
BioGPS Gene:24001 Tiam2
ENSEMBL:ENSMUSG00000023800
ENSEMBL:ENSMUSG00000023800.16 Tiam2
KEGG Gene (Mus musculus):24001 Tiam2
Monarch:24001 Tiam2
NCBI Gene:24001 Tiam2
UCSC:Q6ZPF3 Tiam2
Reference Transcript
RefSeq:XM_006523225.3 Tiam2
RefSeq:NM_001122998.1 Tiam2
RefSeq:NM_011878.2 Tiam2
RefSeq:XM_006523233.1 Tiam2
RefSeq:NM_001286758.1 Tiam2
RefSeq:XM_006523226.1 Tiam2
RefSeq:NM_001286757.1 Tiam2
Other Identifiers
10441361
1420146_at
1423186_at
160796_at
17332695
24001
4327048
4368693
4443686
4451804
4478055
4601763
4608071
4622126
4729967
4770131
4793739
4840474
4857467
4884110
4916367
4980901
5036667
5094951
5121918
5127120
5155626
5173175
5178768
5179639
5185959
5205358
5270510
5300717
5365783
5381426
5435445
5456745
5474515
5538932
5567971
A_51_P256066
GE35981
GO:0005085
GO:0005096
GO:0005515
GO:0005737
GO:0007165
GO:0007264
GO:0016020
GO:0023052
GO:0030027
GO:0030154
GO:0030175
GO:0030426
GO:0030695
GO:0035556
GO:0042995
GO:0043005
GO:0043204
GO:0045202
GO:0048856
GO:0050772
GO:0090630
GO:0098772
ILMN_2714911
ILMN_2836875
mMC020830
Participates
as a member of
RAC1 GEFs [cytosol] (Mus musculus)
GEFs [cytosol] (Mus musculus)
Inferred From
TIAM2 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_001273686.1
,
XP_006523289.1
,
XP_006523296.1
,
NP_036008.2
,
NP_001116470.1
,
XP_006523288.1
,
NP_001273687.1
Ensembl
ENSMUST00000169838
,
ENSMUSP00000125842
,
ENSMUSP00000072020
,
ENSMUST00000072156
,
ENSMUSG00000023800
PRO
Q6ZPF3
MGI
1344338
PDB
3A8P
,
3A8Q
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text