Hoxd4 gene is transcribed

Stable Identifier
R-MMU-5619421
Type
Reaction [BlackBoxEvent]
Species
Mus musculus
Compartment
Summation

The Hoxd4 gene is transcribed to yield mRNA (Featherstone et al. 1988, Popperl and Featherstone 1993, Folberg et al. 1997, Zhang et al. 1997, Folberg et al. 1999, Pitera et al. 1999, Zhang et al. 2000, Wendling et al. 2001, Nolte et al. 2003, Serpente et al. 2005, Kobrossy et al. 2006, Nolte et al. 2006). Hoxd4 mRNA is observed in rhombomere 7 and caudally in spinal cord and prevertebrae of embryos (Featherstone et al. 1988).

Literature References
PubMed ID Title Journal Year
16757478 Interplay between chromatin and trans-acting factors regulating the Hoxd4 promoter during neural differentiation J. Biol. Chem. 2006
17010333 Stereospecificity and PAX6 function direct Hoxd4 neural enhancer activity along the antero-posterior axis Dev. Biol. 2006
12591602 The role of a retinoic acid response element in establishing the anterior neural expression border of Hoxd4 transgenes Mech. Dev. 2003
10579975 Coordinated expression of 3' hox genes during murine embryonal gut development: an enteric Hox code Gastroenterology 1999
10940626 Murine hoxd4 expression in the CNS requires multiple elements including a retinoic acid response element Mech. Dev. 2000
15634700 Direct crossregulation between retinoic acid receptor {beta} and Hox genes during hindbrain segmentation Development 2005
2898782 Hox-5.1 defines a homeobox-containing gene locus on mouse chromosome 2 Proc. Natl. Acad. Sci. U.S.A. 1988
9347914 Elements both 5' and 3' to the murine Hoxd4 gene establish anterior borders of expression in mesoderm and neurectoderm Mech. Dev. 1997
10373014 RARbeta mediates the response of Hoxd4 and Hoxb4 to exogenous retinoic acid Dev. Dyn. 1999
11493525 Roles of retinoic acid receptors in early embryonic morphogenesis and hindbrain patterning Development 2001
8093325 Identification of a retinoic acid response element upstream of the murine Hox-4.2 gene Mol. Cell. Biol. 1993
9360992 Characterization and retinoic acid responsiveness of the murine Hoxd4 transcription unit J. Biol. Chem. 1997
Participants
This entity is regulated by
Orthologous Events