Reactome: A Curated Pathway Database

Mafb and Hoxb1:Pbx1:Pknox1 (Hoxb1:Pbx1:Prep1) activate Hoxa3 expression

Stable Identifier
R-MMU-5619424
Type
Reaction [BlackBoxEvent]
Species
Mus musculus
Compartment
Summation

The transcription factor Mafb (Kreisler, Kmrl) initially activates the Hoxa3 gene in rhombomere 5 (r5) and r6 (Manzanares et al. 1999). Weaker expression is also observed in r7. Hoxa3 autoregulates by binding and activating its own promoter (Manzanares et al. 2001).

Literature References
Participants
Orthologous Events