Reactome: A Curated Pathway Database

Egr2 (Krox20) activates Hoxb2 expression

Stable Identifier
R-MMU-5619430
Type
Reaction [BlackBoxEvent]
Species
Mus musculus
Compartment
Summation

Egr2 (Krox20) binds three sites in the 5' region of the Hoxb2 gene and activates expression in rhombomere 3 (r3) and r5 (Sham et al. 1993, Maconochie et al. 2001, Ferrai et al. 2009). Hoxb1 activates Hoxb2 in r4 and expression is also observed in r6 and r7.

Literature References
Participants
Orthologous Events