Hoxb2 gene is transcribed

Stable Identifier
R-MMU-5619432
Type
Reaction [BlackBoxEvent]
Species
Mus musculus
Compartment
Summation

The Hoxb2 gene is transcribed to yield mRNA (Rubock et al. 1990, Sham et al. 1993, Vesque et al. 1996, Maconochie et al. 1997, Jacobs et al. 1999, Ferretti et al. 2000, Maconochie et al. 2001, Ferrai et al. 2009). Hoxb2 mRNA is observed in rhombomere 3 and caudally in the neural tube and mesoderm derivatives such as lung (Rubock et al. 1990).

Literature References
PubMed ID Title Journal Year
19477923 Induction of HoxB transcription by retinoic acid requires actin polymerization

Ferrai, C, Naum-Onganía, G, Longobardi, E, Palazzolo, M, Disanza, A, Diaz, VM, Crippa, MP, Scita, G, Blasi, F

Mol. Biol. Cell 2009
8895582 Hoxb-2 transcriptional activation in rhombomeres 3 and 5 requires an evolutionarily conserved cis-acting element in addition to the Krox-20 binding site

Vesque, C, Maconochie, M, Nonchev, S, Ariza-McNaughton, L, Kuroiwa, A, Charnay, P, Krumlauf, R

EMBO J. 1996
8093858 The zinc finger gene Krox20 regulates HoxB2 (Hox2.8) during hindbrain segmentation

Sham, MH, Vesque, C, Nonchev, S, Marshall, H, Frain, M, Gupta, RD, Whiting, J, Wilkinson, D, Charnay, P, Krumlauf, R

Cell 1993
9242495 Cross-regulation in the mouse HoxB complex: the expression of Hoxb2 in rhombomere 4 is regulated by Hoxb1

Maconochie, MK, Nonchev, S, Studer, M, Chan, SK, Pöpperl, H, Sham, MH, Mann, RS, Krumlauf, R

Genes Dev. 1997
10654609 Segmental expression of Hoxb2 in r4 requires two separate sites that integrate cooperative interactions between Prep1, Pbx and Hox proteins

Ferretti, E, Marshall, H, Pöpperl, H, Maconochie, M, Krumlauf, R, Blasi, F

Development 2000
10373562 Trimeric association of Hox and TALE homeodomain proteins mediates Hoxb2 hindbrain enhancer activity

Jacobs, Y, Schnabel, CA, Cleary, ML

Mol. Cell. Biol. 1999
11336508 Differences in Krox20-dependent regulation of Hoxa2 and Hoxb2 during hindbrain development

Maconochie, MK, Nonchev, S, Manzanares, M, Marshall, H, Krumlauf, R

Dev. Biol. 2001
1972280 A yeast artificial chromosome containing the mouse homeobox cluster Hox-2

Rubock, MJ, Larin, Z, Cook, M, Papalopulu, N, Krumlauf, R, Lehrach, H

Proc. Natl. Acad. Sci. U.S.A. 1990
Participants
This entity is regulated by
Orthologous Events
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