Hoxb3 gene is transcribed

Stable Identifier
Reaction [BlackBoxEvent]
Mus musculus

The Hoxb3 gene is transcribed to yield mRNA (Sham et al. 1992, Manzanares et al. 1997, Manzanares et al. 2002, Yau et al. 2002, Mechta-Grigoriou et al. 2003). Hoxb3 mRNA is observed strongly in rhombomere 5 (Manzanares et al. 1997, Manzanares et al. 2002) and more weakly in rhombomeres 6 and 7 of the hindbrain (Kwan et al. 2001, Yau et al. 2002). Hoxb3 mRNA is also observed in mesodermal derivatives including lung, stomach, pancreas, and metanephros, and in neural crest derivatives (Sham et al. 1992).

Literature References
PubMed ID Title Journal Year
1582411 Analysis of the murine Hox-2.7 gene: conserved alternative transcripts with differential distributions in the nervous system and the potential for shared regulatory regions

Sham, MH, Hunt, P, Nonchev, S, Papalopulu, N, Graham, A, Boncinelli, E, Krumlauf, R

EMBO J. 1992
11254356 Regulatory analysis of the mouse Hoxb3 gene: multiple elements work in concert to direct temporal and spatial patterns of expression

Kwan, CT, Tsang, SL, Krumlauf, R, Sham, MH

Dev. Biol. 2001
12798298 c-jun regulation and function in the developing hindbrain

Mechta-Grigoriou, F, Giudicelli, F, Pujades, C, Charnay, P, Yaniv, M

Dev. Biol. 2003
9144291 Segmental regulation of Hoxb-3 by kreisler

Manzanares, M, Cordes, S, Kwan, CT, Sham, MH, Barsh, GS, Krumlauf, R

Nature 1997
12482716 Auto/cross-regulation of Hoxb3 expression in posterior hindbrain and spinal cord

Yau, TO, Kwan, CT, Jakt, LM, Stallwood, N, Cordes, S, Sham, MH

Dev. Biol. 2002
11823429 Krox20 and kreisler co-operate in the transcriptional control of segmental expression of Hoxb3 in the developing hindbrain

Manzanares, M, Nardelli, J, Gilardi-Hebenstreit, P, Marshall, H, Giudicelli, F, Martínez-Pastor, MT, Krumlauf, R, Charnay, P

EMBO J. 2002
This entity is regulated by
Orthologous Events