Reactome | Rab11a [cytosol]

Rab11a [cytosol]

Stable Identifier

R-MMU-5623395

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

cytosol

Synonyms

RAB11A, P62492

Locations in the PathwayBrowser

Expand all

Organelle biogenesis and maintenance (Mus musculus)

- Cilium Assembly (Mus musculus)
  - Anchoring of the basal body to the plasma membrane (Mus musculus)
    - CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body (Mus musculus)
      - RAB3IP:RAB11A:GTP:Golgi-derived vesicle [Golgi-associated vesicle membrane] (Mus musculus)
        
        RAB11A:GTP:Golgi derived vesicle [Golgi-associated vesicle membrane] (Mus musculus)
        
        RAB11A:GTP [cytosol] (Mus musculus)
        
        Rab11a [cytosol] (Mus musculus)
      - basal body:transition zone proteins:RAB3IP:RAB11A:GTP:Golgi-derived vesicle [cytosol] (Mus musculus)
        
        RAB3IP:RAB11A:GTP:Golgi-derived vesicle [Golgi-associated vesicle membrane] (Mus musculus)
        
        RAB11A:GTP:Golgi derived vesicle [Golgi-associated vesicle membrane] (Mus musculus)
        
        RAB11A:GTP [cytosol] (Mus musculus)
        
        Rab11a [cytosol] (Mus musculus)
    - RAB11A:GTP-containing Golgi vesicles recruit RAB3IP (Mus musculus)
      - RAB11A:GTP:Golgi derived vesicle [Golgi-associated vesicle membrane] (Mus musculus)
        
        RAB11A:GTP [cytosol] (Mus musculus)
        
        Rab11a [cytosol] (Mus musculus)
      - RAB3IP:RAB11A:GTP:Golgi-derived vesicle [Golgi-associated vesicle membrane] (Mus musculus)
        
        RAB11A:GTP:Golgi derived vesicle [Golgi-associated vesicle membrane] (Mus musculus)
        
        RAB11A:GTP [cytosol] (Mus musculus)
        
        Rab11a [cytosol] (Mus musculus)
    - RAB3IP stimulates nucleotide exchange on RAB8A (Mus musculus)
      - basal body:transition zone proteins:RAB3IP:RAB11A:GTP:Golgi-derived vesicle [cytosol] (Mus musculus)
        
        RAB3IP:RAB11A:GTP:Golgi-derived vesicle [Golgi-associated vesicle membrane] (Mus musculus)
        
        RAB11A:GTP:Golgi derived vesicle [Golgi-associated vesicle membrane] (Mus musculus)
        
        RAB11A:GTP [cytosol] (Mus musculus)
        
        Rab11a [cytosol] (Mus musculus)
  - Cargo trafficking to the periciliary membrane (Mus musculus)
    - VxPx cargo-targeting to cilium (Mus musculus)
      - ASAP1 recruits RAB11FIP3 and RAB11 to the ciliary targeting complex (Mus musculus)
        
        RAB11A:GTP [cytosol] (Mus musculus)
        
        Rab11a [cytosol] (Mus musculus)
        
        RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:ARF4:GTP:VxPx-containing ciliary membrane proteins [Golgi membrane] (Mus musculus)
        
        RAB11A:GTP [cytosol] (Mus musculus)
        
        Rab11a [cytosol] (Mus musculus)
      - ASAP1 stimulates GTPase activity of ARF4 (Mus musculus)
        
        RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:ARF4:GTP:VxPx-containing ciliary membrane proteins [Golgi membrane] (Mus musculus)
        
        RAB11A:GTP [cytosol] (Mus musculus)
        
        Rab11a [cytosol] (Mus musculus)
        
        RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi membrane] (Mus musculus)
        
        RAB11A:GTP [cytosol] (Mus musculus)
        
        Rab11a [cytosol] (Mus musculus)
      - Cargo-carrying vesicles bud from the TGN (Mus musculus)
        
        RAB8A:GTP:RAB3IP:RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi membrane] (Mus musculus)
        
        RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi membrane] (Mus musculus)
        
        RAB11A:GTP [cytosol] (Mus musculus)
        
        Rab11a [cytosol] (Mus musculus)
        
        RAB8A:GTP:RAB3IP:RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi-associated vesicle membrane] (Mus musculus)
        
        RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi-associated vesicle membrane] (Mus musculus)
        
        RAB11A:GTP [cytosol] (Mus musculus)
        
        Rab11a [cytosol] (Mus musculus)
      - RAB3IP and RAB8A bind to the ciliary targeting complex (Mus musculus)
        
        RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi membrane] (Mus musculus)
        
        RAB11A:GTP [cytosol] (Mus musculus)
        
        Rab11a [cytosol] (Mus musculus)
        
        RAB8A:GDP:RAB3IP:RAB11A:GTP:FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi membrane] (Mus musculus)
        
        RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi membrane] (Mus musculus)
        
        RAB11A:GTP [cytosol] (Mus musculus)
        
        Rab11a [cytosol] (Mus musculus)
      - RAB3IP stimulates nucleotide exchange on RAB8A (Mus musculus)
        
        RAB8A:GDP:RAB3IP:RAB11A:GTP:FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi membrane] (Mus musculus)
        
        RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi membrane] (Mus musculus)
        
        RAB11A:GTP [cytosol] (Mus musculus)
        
        Rab11a [cytosol] (Mus musculus)
        
        RAB8A:GTP:RAB3IP:RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi membrane] (Mus musculus)
        
        RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi membrane] (Mus musculus)
        
        RAB11A:GTP [cytosol] (Mus musculus)
        
        Rab11a [cytosol] (Mus musculus)
      - The exocyst complex binds to RAB3IP in the ciliary targeting complex (Mus musculus)
        
        RAB8A:GTP:RAB3IP:RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi-associated vesicle membrane] (Mus musculus)
        
        RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi-associated vesicle membrane] (Mus musculus)
        
        RAB11A:GTP [cytosol] (Mus musculus)
        
        Rab11a [cytosol] (Mus musculus)
        
        exocyst complex:RAB8A:GTP:RAB3IP:RAB11:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi-associated vesicle membrane] (Mus musculus)
        
        RAB8A:GTP:RAB3IP:RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi-associated vesicle membrane] (Mus musculus)
        
        RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi-associated vesicle membrane] (Mus musculus)
        
        RAB11A:GTP [cytosol] (Mus musculus)
        
        Rab11a [cytosol] (Mus musculus)
      - VxPx-containing ciliary membrane proteins are delivered to the ciliary membrane (Mus musculus)
        
        exocyst complex:RAB8A:GTP:RAB3IP:RAB11:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi-associated vesicle membrane] (Mus musculus)
        
        RAB8A:GTP:RAB3IP:RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi-associated vesicle membrane] (Mus musculus)
        
        RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi-associated vesicle membrane] (Mus musculus)
        
        RAB11A:GTP [cytosol] (Mus musculus)
        
        Rab11a [cytosol] (Mus musculus)

External Reference Information

External Reference

UniProt:P62492 Rab11a

Gene Names

Rab11a, Rab11

Chain

initiator methionine:1, chain:2-213, propeptide:214-216

Reference Genes

BioGPS Gene:53869 Rab11a

ENSEMBL:ENSMUSG00000004771 Rab11a

KEGG Gene (Mus musculus):53869 Rab11a

Monarch:53869 Rab11a

NCBI Gene:53869 Rab11a

UCSC:P62492 Rab11a

Reference Transcript

RefSeq:NM_017382.5 Rab11a

Other Identifiers

10594480

113031_at

1434549_at

1449256_a_at

167286_at

17528202

4520834

4622276

4643513

4670069

4930310

4974098

4984107

5051881

5168397

5283421

5299312

53869

5535886

92854_at

96238_at

A_51_P277505

A_52_P389310

A_52_P444162

D50500_f_at

GE42757

GO:0000166

GO:0000278

GO:0000902

GO:0000922

GO:0003674

GO:0003924

GO:0005515

GO:0005525

GO:0005575

GO:0005576

GO:0005615

GO:0005622

GO:0005737

GO:0005739

GO:0005768

GO:0005771

GO:0005794

GO:0005802

GO:0005813

GO:0005815

GO:0005828

GO:0005856

GO:0005886

GO:0006810

GO:0006887

GO:0007010

GO:0007049

GO:0007059

GO:0007080

GO:0007267

GO:0008017

GO:0008092

GO:0008150

GO:0010634

GO:0010796

GO:0010971

GO:0015031

GO:0016020

GO:0016192

GO:0022607

GO:0030133

GO:0030154

GO:0030424

GO:0030659

GO:0030953

GO:0031175

GO:0031410

GO:0031489

GO:0031982

GO:0032154

GO:0032402

GO:0032465

GO:0032991

GO:0034451

GO:0036258

GO:0040007

GO:0040011

GO:0043167

GO:0043226

GO:0043231

GO:0043473

GO:0045335

GO:0045773

GO:0048169

GO:0048471

GO:0048856

GO:0048870

GO:0051223

GO:0051276

GO:0051301

GO:0051650

GO:0055037

GO:0055038

GO:0060627

GO:0070062

GO:0072594

GO:0072659

GO:0090150

GO:0090307

GO:0098685

GO:0098837

GO:0098887

GO:0098978

GO:0099003

GO:0140014

GO:0150093

GO:1903078

GO:1990182

ILMN_1230413

ILMN_1258343

Msa.19548.0_s_at

aa530037_at

mMC015258

mMR030625

Participant Of

hasComponent

RAB11A:GTP [cytosol]

hasMember

RABs [cytosol]

Other forms of this molecule

Rab11a [recycling endosome membrane]

Rab11a [cytosol]

GGC-Rab11a [cytoplasmic vesicle membrane]

Inferred From

RAB11A [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_059078.2

Ensembl

ENSMUSP00000129163, ENSMUSG00000004771, ENSMUST00000172298

PRO

P62492

MGI

1858202

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q62739	1	Rab3ip [cytosol] (R-RNO-5617610)	0.556	4
UniProt:P35438 Grin1	3	Grin1 [endoplasmic reticulum membrane] (R-MMU-9610359) Grin1 [plasma membrane] (R-MMU-3928395) Grin1 [transport vesicle membrane] (R-MMU-9610566)	0.462	2

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