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What is Reactome ?
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PKN2 [cytosol]
Stable Identifier
R-MMU-5623612
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
cytosol
Synonyms
Q8BWW9
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Mus musculus)
Cellular responses to mechanical stimuli (Mus musculus)
Response of endothelial cells to shear stress (Mus musculus)
High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells (Mus musculus)
PDPK1 (PDK1) phosphorylates PKN2 on threonine-816 (Mus musculus)
PKN2 [cytosol] (Mus musculus)
Signal Transduction (Mus musculus)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Mus musculus)
Signaling by Rho GTPases (Mus musculus)
RHO GTPase Effectors (Mus musculus)
RHO GTPases activate PKNs (Mus musculus)
PDPK1 phosphorylates PKN1,2,3 (Mus musculus)
RHOA,RHOB,RHOC,RAC1:GTP:PKN1-3:PDPK1:PIP3 [plasma membrane] (Mus musculus)
RHOA,RHOB,RHOC,RAC1:GTP:PKN1-3 [plasma membrane] (Mus musculus)
PKN1-3 [cytosol] (Mus musculus)
PKN2 [cytosol] (Mus musculus)
RHOA, RHOB, RHOC and RAC1 bind PKN1, PKN2 or PKN3 (Mus musculus)
PKN1-3 [cytosol] (Mus musculus)
PKN2 [cytosol] (Mus musculus)
RHOA,RHOB,RHOC,RAC1:GTP:PKN1-3 [plasma membrane] (Mus musculus)
PKN1-3 [cytosol] (Mus musculus)
PKN2 [cytosol] (Mus musculus)
RHOA,RHOB,RHOC,RAC1:GTP:PKN1,2,3 binds PDPK1:PIP3 (Mus musculus)
RHOA,RHOB,RHOC,RAC1:GTP:PKN1-3 [plasma membrane] (Mus musculus)
PKN1-3 [cytosol] (Mus musculus)
PKN2 [cytosol] (Mus musculus)
RHOA,RHOB,RHOC,RAC1:GTP:PKN1-3:PDPK1:PIP3 [plasma membrane] (Mus musculus)
RHOA,RHOB,RHOC,RAC1:GTP:PKN1-3 [plasma membrane] (Mus musculus)
PKN1-3 [cytosol] (Mus musculus)
PKN2 [cytosol] (Mus musculus)
RHO GTPase cycle (Mus musculus)
RAC1 GTPase cycle (Mus musculus)
RAC1 binds effectors at the plasma membrane (Mus musculus)
RAC1 effectors [cytosol] (Mus musculus)
PKN2 [cytosol] (Mus musculus)
RAC1:GTP:RAC1 effectors [plasma membrane] (Mus musculus)
RAC1 effectors [cytosol] (Mus musculus)
PKN2 [cytosol] (Mus musculus)
RHOA GTPase cycle (Mus musculus)
RHOA binds effectors at the plasma membrane (Mus musculus)
RHOA plasma membrane effectors [cytosol] (Mus musculus)
PKN2 [cytosol] (Mus musculus)
RHOA:GTP:cytosolic RHOA effectors [plasma membrane] (Mus musculus)
RHOA plasma membrane effectors [cytosol] (Mus musculus)
PKN2 [cytosol] (Mus musculus)
RHOB GTPase cycle (Mus musculus)
RHOB binds effectors at the plasma membrane (Mus musculus)
RHOB effectors (plasma membrane) [cytosol] (Mus musculus)
PKN2 [cytosol] (Mus musculus)
RHOB:GTP:cytosolic RHOB effectors [plasma membrane] (Mus musculus)
RHOB effectors (plasma membrane) [cytosol] (Mus musculus)
PKN2 [cytosol] (Mus musculus)
RHOC GTPase cycle (Mus musculus)
RHOC binds effectors at the plasma membrane (Mus musculus)
RHOC effectors [cytosol] (Mus musculus)
PKN2 [cytosol] (Mus musculus)
RHOC:GTP:RHOC effectors [plasma membrane] (Mus musculus)
RHOC effectors [cytosol] (Mus musculus)
PKN2 [cytosol] (Mus musculus)
External Reference Information
External Reference
UniProt:Q8BWW9
Reference Genes
BioGPS Gene:109333
ENSEMBL:ENSMUSG00000004591
KEGG:mmu:109333
Monarch:109333
NCBI Gene:109333
UCSC:Q8BWW9
Reference Transcript
RefSeq:NM_178654.4
Other Identifiers
104503_at
10502484
109333
109357_at
135668_at
140939_at
1437295_at
1437296_at
163931_at
17410775
4318456
4356015
4361813
4443429
4500312
4501673
4517249
4539031
4542426
4576123
4603863
4634586
4703647
4724855
4734177
4806018
4837390
4959361
5006350
5006410
5007992
5031580
5049827
5058744
5059202
5062008
5116930
5130464
5133134
5213838
5221327
5225016
5229107
5229834
5261804
5263389
5286392
5397863
5415575
5450040
5453333
5477286
5504627
5523186
5615249
A_51_P195947
A_52_P261160
A_52_P290629
A_52_P309423
A_55_P2136556
A_55_P2796896
GE1528399
GO:0003824
GO:0004672
GO:0004674
GO:0004697
GO:0005515
GO:0005524
GO:0005634
GO:0005654
GO:0005737
GO:0005813
GO:0005815
GO:0005829
GO:0005856
GO:0005886
GO:0006468
GO:0006915
GO:0007155
GO:0007165
GO:0010631
GO:0012501
GO:0016020
GO:0016301
GO:0016604
GO:0016740
GO:0030027
GO:0030030
GO:0030496
GO:0031267
GO:0032154
GO:0032467
GO:0032991
GO:0034330
GO:0035556
GO:0042826
GO:0042995
GO:0043226
GO:0043296
GO:0043297
GO:0045070
GO:0045111
GO:0045931
GO:0048471
GO:0048870
GO:0051301
GO:0070063
GO:0070161
GO:0106310
GO:0140096
GO:2000145
ILMN_1241870
ILMN_2428290
ILMN_2679815
ILMN_2768805
ILMN_2972239
Msa.33934.0_s_at
mMC016884
mMR029209
Participates
as a member of
RHOA plasma membrane effectors [cytosol] (Mus musculus)
RHOC effectors [cytosol] (Mus musculus)
RAC1 effectors [cytosol] (Mus musculus)
RHOB effectors (plasma membrane) [cytosol] (Mus musculus)
PKN1-3 [cytosol] (Mus musculus)
as an input of
PDPK1 (PDK1) phosphorylates PKN2 on threonine-816 (Mus musculus)
Other forms of this molecule
phospho-p-T816-PKN2 [cytosol]
Inferred From
PKN2 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_848769.2
ENSEMBL
ENSMUSP00000039566
,
ENSMUST00000043812
PRO
Q8BWW9
MGI
109211
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